TGF-beta 3 Antibody | R&D Systems MAB243 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

TGF-beta 3 Antibody

catalog :

MAB243

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

20724

reactivity :

human

application :

western blot, immunohistochemistry, neutralization

citations: 6

Reference
Okamura T, Sumitomo S, Morita K, Iwasaki Y, Inoue M, Nakachi S, et al. TGF-Î²3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses. Nat Commun. 2015;6:6329 pubmed publisher
Yin H, Lo J, Kim J, Marsh E, Kim J, Ghosh A, et al. Expression profiling of nuclear receptors identifies key roles of NR4A subfamily in uterine fibroids. Mol Endocrinol. 2013;27:726-40 pubmed publisher
Ozturk F, Li Y, Zhu X, Guda C, Nawshad A. Systematic analysis of palatal transcriptome to identify cleft palate genes within TGF?3-knockout mice alleles: RNA-Seq analysis of TGF?3 Mice. BMC Genomics. 2013;14:113 pubmed publisher
Gregory P, Bracken C, Smith E, Bert A, Wright J, Roslan S, et al. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell. 2011;22:1686-98 pubmed publisher
Arciniegas E, Neves C, Candelle D, Parada D. Differential versican isoforms and aggrecan expression in the chicken embryo aorta. Anat Rec A Discov Mol Cell Evol Biol. 2004;279:592-600 pubmed
Liu X, Kohyama T, Wang H, Zhu Y, Wen F, Kim H, et al. Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells. Am J Physiol Lung Cell Mol Physiol. 2002;282:L1049-56 pubmed

product information

brand :

R&D Systems

master code :

MAB243

SKU :

MAB243-100

product name :

TGF-beta 3 Antibody

description :

The TGF-beta 3 Antibody from R&D Systems is a mouse monoclonal antibody to TGF-beta 3. This antibody reacts with multi-species. The TGF-beta 3 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Neutralization.

target :

TGF-beta 3

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

20724

conjugate :

Unconjugated

host :

Mouse

immunogen :

Spodoptera frugiperda, Sf 21 (baculovirus) derived recombinant human TGF-beta 3, Ala301-Ser412 (Tyr340Phe), Accession # P10600

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Multi-Species

specificity :

Detects TGF-beta 3 from multiple species in direct ELISAs and Western blots. In Western blots, less than 25% cross-reactivity with recombinant human (rh) TGF-beta 1.2 and rhTGF-beta 2 is observed, and less than 2% cross-reactivity with recombinant amphibian TGF-beta 5 and recombinant human TGF-beta 1 is observed. Neutralizes the biological activity of TGF-beta 3 but not TGF-beta 1, TGF-beta 2, or TGF-beta 5.

gene symbol :

TGFB3

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB243

accessionNumbers :

P10600

applications :

Western Blot, Immunohistochemistry, Neutralization

2020 USD :

339

2021 USD :

359 USD

alt names :

ARVD, ARVD1, FLJ16571, LDS5, RNHF, TGFB3, TGFbeta 3, TGF-beta3, TGF-beta-3, transforming growth factor beta-3, transforming growth factor, beta 3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.