TGF┐▀3 Antibody | R&D Systems MAB243-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

TGF┐▀3 Antibody

catalog :

MAB243-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

20724

reactivity :

human, mouse, dogs, chicken

application :

western blot, immunohistochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 8

Reference
Kanaji N, Yokohira M, Watanabe N, Kadowaki N, Bandoh S. Transforming Growth Factor-Beta Produced by Non-small Cell Lung Cancer Cells Contributes to Lung Fibroblast Contractile Phenotype. Anticancer Res. 2018;38:2007-2014 pubmed
Okamura T, Sumitomo S, Morita K, Iwasaki Y, Inoue M, Nakachi S, et al. TGF-Î²3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses. Nat Commun. 2015;6:6329 pubmed publisher
Yin H, Lo J, Kim J, Marsh E, Kim J, Ghosh A, et al. Expression profiling of nuclear receptors identifies key roles of NR4A subfamily in uterine fibroids. Mol Endocrinol. 2013;27:726-40 pubmed publisher
Ozturk F, Li Y, Zhu X, Guda C, Nawshad A. Systematic analysis of palatal transcriptome to identify cleft palate genes within TGF?3-knockout mice alleles: RNA-Seq analysis of TGF?3 Mice. BMC Genomics. 2013;14:113 pubmed publisher
Gregory P, Bracken C, Smith E, Bert A, Wright J, Roslan S, et al. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell. 2011;22:1686-98 pubmed publisher
Amarir S, Marx M, Calothy G. Notch signaling activation suppresses v-Src-induced transformation of neural cells by restoring TGF-β-mediated differentiation. PLoS ONE. 2010;5:e13572 pubmed publisher
Arciniegas E, Neves C, Candelle D, Parada D. Differential versican isoforms and aggrecan expression in the chicken embryo aorta. Anat Rec A Discov Mol Cell Evol Biol. 2004;279:592-600 pubmed
Liu X, Kohyama T, Wang H, Zhu Y, Wen F, Kim H, et al. Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells. Am J Physiol Lung Cell Mol Physiol. 2002;282:L1049-56 pubmed

product information

brand :

R&D Systems

master code :

MAB243

SKU :

MAB243-100

product name :

TGF┐▀3 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The TGF¿ß3 Antibody from R&D Systems is a mouse monoclonal antibody to TGF-beta 3. This antibody reacts with avian - chicken,canine,human,mouse,multi-species. The TGF¿ß3 Antibody has been validated for the following applications: ELISA Development,Western Blot,Neutralization,Immunohistochemistry.

target :

TGF-beta 3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

20724

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 8-25 ug/mL, Neutralization 0.1-0.3 ug/mL

host :

Mouse

immunogen :

Spodoptera frugiperda, Sf 21 (baculovirus) derived recombinant human TGF┐▀3, Ala301-Ser412 (Tyr340Phe), Accession # P10600

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Avian - Chicken,Canine,Human,Mouse,Multi-Species

specificity :

Detects TGF┐▀3 from multiple species in direct ELISAs and Western blots. In Western blots, less than 25% cross-reactivity with recombinant human (rh) TGF┐▀1.2 and rhTGF┐▀2 is observed, and less than 2% cross-reactivity with recombinant amphibian TGF┐▀5 and recombinant human TGF┐▀1 is observed. Neutralizes the biological activity of TGF┐▀3 but not TGF┐▀1, TGF┐▀2, or TGF┐▀5.

gene symbol :

TGFB3

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

TGF-ss3 Inhibition of IL-4-dependent Cell Proliferation and Neutralization by TGF-ss3 Antibody.

accessionNumbers :

P10600

applications :

ELISA Development,Immunohistochemistry,Western Blot,Neutralization

USD :

469 USD

alt names :

ARVD, ARVD1, FLJ16571, LDS5, RNHF, TGFB3, TGFbeta 3, TGF-beta3, TGF-beta-3, transforming growth factor beta-3, transforming growth factor, beta 3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage