TGF┐▀1 Antibody | R&D Systems MAB2401-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

TGF┐▀1 Antibody

catalog :

MAB2401-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

141322

reactivity :

human, mouse, rat, chimpanzee

application :

western blot, neutralization

more info or order :

R&D Systems product webpage

citations: 11

Reference
Liu J, Zhu S, Zeng L, Li J, Klionsky D, Kroemer G, et al. DCN released from ferroptotic cells ignites AGER-dependent immune responses. Autophagy. 2021;:1-14 pubmed publisher
Liu G, Shea C, Jones J, Price G, Warren W, Lonie E, et al. Praliciguat inhibits progression of diabetic nephropathy in ZSF1 rats and suppresses inflammation and apoptosis in human renal proximal tubular cells. Am J Physiol Renal Physiol. 2020;319:F697-F711 pubmed publisher
Mancini D, Monteagudo J, Suárez Fariñas M, Bander J, Varshney R, Gonzalez J, et al. New methodologies to accurately assess circulating active transforming growth factor-β1 levels: implications for evaluating heart failure and the impact of left ventricular assist devices. Transl Res. 2018;192:15-29 pubmed publisher
Laurence J, Elhadad S, Robison T, Terry H, Varshney R, Woolington S, et al. HIV protease inhibitor-induced cardiac dysfunction and fibrosis is mediated by platelet-derived TGF-β1 and can be suppressed by exogenous carbon monoxide. PLoS ONE. 2017;12:e0187185 pubmed publisher
Cai P, Kovacs L, Dong S, Wu G, Su Y. BMP4 inhibits PDGF-induced proliferation and collagen synthesis via PKA-mediated inhibition of calpain-2 in pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2017;312:L638-L648 pubmed publisher
Le Gendre O, Sookdeo A, Duliepre S, Utter M, Frias M, Foster D. Suppression of AKT phosphorylation restores rapamycin-based synthetic lethality in SMAD4-defective pancreatic cancer cells. Mol Cancer Res. 2013;11:474-81 pubmed publisher
Zhu Y, Colak T, Shenoy M, Liu L, Mehta K, Pai R, et al. Transforming growth factor beta induces sensory neuronal hyperexcitability, and contributes to pancreatic pain and hyperalgesia in rats with chronic pancreatitis. Mol Pain. 2012;8:65 pubmed publisher
Alexander S, Watt F, Sawaji Y, Hermansson M, Saklatvala J. Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB. Arthritis Rheum. 2007;56:3715-25 pubmed
Bayry J, Triebel F, Kaveri S, Tough D. Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells. J Immunol. 2007;178:4184-93 pubmed
Manigold T, Shin E, Mizukoshi E, Mihalik K, Murthy K, Rice C, et al. Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C. Blood. 2006;107:4424-32 pubmed
Rosini L, Matlack R, Taylor J, Howell K, Yeh K, Pennello A, et al. Nonlymphoid peritoneal cells suppress the T cell response to Mls. Immunobiology. 2004;209:575-84 pubmed

product information

master code :

MAB2401

SKU :

MAB2401-100

product name :

TGF┐▀1 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The TGF¿ß1 Antibody from R&D Systems is a mouse monoclonal antibody to TGF-beta 1. This antibody reacts with human,mouse,multi-species,porcine,primate - pan troglodytes (chimpanzee),rat. The TGF¿ß1 Antibody has been validated for the following applications: Neutralization Control,Western Blot,Neutralization.

target :

TGF-beta 1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

141322

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human TGF┐▀1

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Multi-Species,Porcine,Primate - Pan troglodytes (Chimpanzee),Rat

specificity :

Detects multiple species of TGF┐▀1 in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant human (rh) TGF-alpha , rhTGF┐▀2, rhTGF┐▀3, rhTGF┐▀5, rhLAP (TGF┐▀1), rhART, rhNeurturin, or recombinant mouse TRANCE.

gene symbol :

TGFB1

applications :

Neutralization Control,Western Blot,Neutralization

USD :

469 USD

alt names :

CEDLAP, DPD1, latency-associated peptide, TGF beta, TGF beta1, TGFB, TGFB1, TGFbeta, TGFbeta 1, TGF-beta 1 protein, TGF-beta-1, transforming growth factor beta-1, transforming growth factor, beta 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage