Human TIM-3 Antibody | R&D Systems MAB23651 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TIM-3 Antibody

catalog :

MAB23651

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

344801

reactivity :

human

application :

western blot, neutralization, immunoprecipitation, flow cytometry, blocking or activating experiments

more info or order :

R&D Systems product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; fig 3a	Abdel Mohsen M, Chavez L, Tandon R, Chew G, Deng X, Danesh A, et al. Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation. PLoS Pathog. 2016;12:e1005677 pubmed publisher
	Tang L, Shao H, Wu Y, Wang J, Qian X, He L, et al. Dominant negative TGFβ receptor II and truncated TIM3 enhance the antitumor efficacy of CAR-T-cell therapy in prostate cancer. Int Immunopharmacol. 2023;124:110807 pubmed publisher
	Motavalli R, Hosseini M, Soltani Zangbar M, Karimi A, Sadeghi M, Dolati S, et al. Evaluation of the immune checkpoint factors in idiopathic membranous nephropathy. Mol Cell Probes. 2023;69:101914 pubmed publisher
	Ohmura H, Yamaguchi K, Hanamura F, Ito M, Makiyama A, Uchino K, et al. OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody. Br J Cancer. 2020;122:1507-1517 pubmed publisher
	Zhao D, Guo M, Liu B, Lin Q, Xie T, Zhang Q, et al. Frontline Science: Tim-3-mediated dysfunctional engulfment of apoptotic cells in SLE. J Leukoc Biol. 2017;102:1313-1322 pubmed publisher
	Schwartz J, Clayton K, Mujib S, Zhang H, Rahman A, Liu J, et al. Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9. J Immunol. 2017;198:3181-3194 pubmed publisher

product information

master code :

MAB23651

SKU :

MAB23651

product name :

Human TIM-3 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human TIM-3 Antibody from R&D Systems is a rat monoclonal antibody to TIM-3. This antibody reacts with human. The Human TIM-3 Antibody has been validated for the following applications: Bioassay,Flow Cytometry,Immunoprecipitation,Western Blot,Agonist Activity,Neutralization.

target :

TIM-3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

344801

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TIM-3, Met1-Arg200, Accession # Q8TDQ0

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects recombinant human TIM-3 in direct ELISAs and Western blots.

gene symbol :

HAVCR2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

Q8TDQ0

applications :

Bioassay,Flow Cytometry,Immunoprecipitation,Western Blot,Agonist Activity,Neutralization

USD :

479 USD

alt names :

CD366, FLJ14428, HAVcr-2, HAVCR2, hepatitis A virus cellular receptor 2, kidney injury molecule-3, KIM-3, SPTCL, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain-containing protein 3, TIM 3, Tim-3, TIM3, TIM3 T-cell membrane protein 3, TIMD3, TIMD-3, TIMD3KIM-3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage