Human EGF Antibody | R&D Systems MAB236-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human EGF Antibody

catalog :

MAB236-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10825

reactivity :

human

application :

western blot, immunohistochemistry, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 16

Reference
Bauer L, Edwards J, Heil A, Dewitt S, Biebermann H, Aeschlimann D, et al. Mesenchymal Transglutaminase 2 Activates Epithelial ADAM17: Link to G-Protein-Coupled Receptor 56 (ADGRG1) Signalling. Int J Mol Sci. 2024;25: pubmed publisher
Muliaditan T, Halim L, Whilding L, Draper B, Achkova D, Kausar F, et al. Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors. Cell Rep Med. 2021;2:100457 pubmed publisher
Ticiani E, Gingrich J, Pu Y, Vettathu M, Davis J, Martin D, et al. Bisphenol S and Epidermal Growth Factor Receptor Signaling in Human Placental Cytotrophoblasts. Environ Health Perspect. 2021;129:27005 pubmed publisher
Morgan E, Scarth J, Patterson M, Wasson C, Hemingway G, Barba Moreno D, et al. E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer. Cell Death Differ. 2021;28:1669-1687 pubmed publisher
Chronopoulos A, Thorpe S, Cortés E, Lachowski D, Rice A, Mykuliak V, et al. Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway. Nat Mater. 2020;19:669-678 pubmed publisher
Nagano H, Tomida C, Yamagishi N, Teshima Kondo S. VEGFR-1 Regulates EGF-R to Promote Proliferation in Colon Cancer Cells. Int J Mol Sci. 2019;20: pubmed publisher
Jeong S, Kim B, Lau H, Kim A. Gelatin-Alginate Complexes for EGF Encapsulation: Effects of H-Bonding and Electrostatic Interactions. Pharmaceutics. 2019;11: pubmed publisher
Müller Deubert S, Seefried L, Krug M, Jakob F, Ebert R. Epidermal growth factor as a mechanosensitizer in human bone marrow stromal cells. Stem Cell Res. 2017;24:69-76 pubmed publisher
Arnli M, Backer Grøndahl T, Ytterhus B, Granli U, Lydersen S, Gulati S, et al. Expression and clinical value of EGFR in human meningiomas. Peerj. 2017;5:e3140 pubmed publisher
Iwata Y, Kobayashi T, Kuroda M, Mizoguchi Y, Arima M, Numata S, et al. Case report of multiple pustules of the bilateral lower limbs caused by a granulocyte colony-stimulating factor-producing solid pseudopapillary tumour of the pancreas. Br J Dermatol. 2017;177:1122-1126 pubmed publisher
Zhang Z, Dong Z, Lauxen I, Filho M, Nor J. Endothelial cell-secreted EGF induces epithelial to mesenchymal transition and endows head and neck cancer cells with stem-like phenotype. Cancer Res. 2014;74:2869-81 pubmed publisher
Yu C, Yu C. Photodynamic therapy with 5-aminolevulinic acid (ALA) impairs tumor initiating and chemo-resistance property in head and neck cancer-derived cancer stem cells. PLoS ONE. 2014;9:e87129 pubmed publisher
Nadworny P, Wang J, Tredget E, Burrell R. Anti-inflammatory activity of nanocrystalline silver-derived solutions in porcine contact dermatitis. J Inflamm (Lond). 2010;7:13 pubmed publisher
Sakaguchi M, Sonegawa H, Murata H, Kitazoe M, Futami J, Kataoka K, et al. S100A11, an dual mediator for growth regulation of human keratinocytes. Mol Biol Cell. 2008;19:78-85 pubmed
Li Y, Fan J, Chen M, Li W, Woodley D. Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration. J Invest Dermatol. 2006;126:2096-105 pubmed
Groschl M, Topf H, Kratzsch J, Dotsch J, Rascher W, Rauh M. Salivary leptin induces increased expression of growth factors in oral keratinocytes. J Mol Endocrinol. 2005;34:353-66 pubmed

product information

brand :

R&D Systems

master code :

MAB236

SKU :

MAB236-100

product name :

Human EGF Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human EGF Antibody from R&D Systems is a mouse monoclonal antibody to EGF. This antibody reacts with human,porcine. The Human EGF Antibody has been validated for the following applications: Western Blot,Control,Neutralization,Functional Assay,Immunohistochemistry,Immunohistochemistry-Paraffin.

target :

EGF

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

10825

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 8-25 ug/mL, Neutralization 0.05-0.1 ug/mL

host :

Mouse

immunogen :

E. coli -derived recombinant human EGF

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Porcine

specificity :

Detects human EGF in direct ELISAs. Detects human EGF and rat EGF in Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) HB-EGF or rhTGF-alpha is observed. In Western blots, no cross-reactivity with recombinant mouse EGF is observed.

gene symbol :

EGF

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Recombinant Human and Rat EGF antibody by Western Blot.

applications :

Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Control,Neutralization,Functional Assay

USD :

499 USD

alt names :

beta-urogastrone, epidermal growth factor, epidermal growth factor (beta-urogastrone), hEGF, HOMG4, pro-epidermal growth factor, URG, Urogastrone

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage