Human/Mouse Pin1 Antibody | R&D Systems MAB2294 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse Pin1 Antibody

catalog :

MAB2294

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

257417

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 12

Reference
Pelicci S, Furia L, Pelicci P, Faretta M. Correlative Multi-Modal Microscopy: A Novel Pipeline for Optimizing Fluorescence Microscopy Resolutions in Biological Applications. Cells. 2023;12: pubmed publisher
Wang Y, Hsiao W, Wang S. The fission yeast Pin1 peptidyl-prolyl isomerase promotes dissociation of Sty1 MAPK from RNA polymerase II and recruits Ssu72 phosphatase to facilitate oxidative stress induced transcription. Nucleic Acids Res. 2021;49:805-817 pubmed publisher
Daza Martin M, Starowicz K, Jamshad M, Tye S, Ronson G, Mackay H, et al. Isomerization of BRCA1-BARD1 promotes replication fork protection. Nature. 2019;571:521-527 pubmed publisher
Chen X, Liu X, Deng B, Martinka M, Zhou Y, Lan X, et al. Cytoplasmic Pin1 expression is increased in human cutaneous melanoma and predicts poor prognosis. Sci Rep. 2018;8:16867 pubmed publisher
Shen Z, Hu J, Kashi V, Bochkov Y, Gern J, Malter J. TLR-7 Stress Signaling in Differentiating and Mature Eosinophils Is Mediated by the Prolyl Isomerase Pin1. J Immunol. 2018;201:3503-3513 pubmed publisher
Stallings N, O Neal M, Hu J, Kavalali E, Bezprozvanny I, Malter J. Pin1 mediates A?42-induced dendritic spine loss. Sci Signal. 2018;11: pubmed publisher
Kruiswijk F, Hasenfuss S, Sivapatham R, Baar M, Putavet D, Naipal K, et al. Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling. Oncogene. 2016;35:2166-77 pubmed publisher
Ghosh A, Saminathan H, Kanthasamy A, Anantharam V, Jin H, Sondarva G, et al. The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease. J Biol Chem. 2013;288:21955-71 pubmed publisher
Nishi M, Akutsu H, Masui S, Kondo A, Nagashima Y, Kimura H, et al. A distinct role for Pin1 in the induction and maintenance of pluripotency. J Biol Chem. 2011;286:11593-603 pubmed publisher
Brenkman A, de Keizer P, van den Broek N, van der Groep P, van Diest P, van der Horst A, et al. The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressors. Cancer Res. 2008;68:7597-605 pubmed publisher
Liu T, Huang Y, Likhotvorik R, Keshvara L, Hoyt D. Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells. Am J Physiol Cell Physiol. 2008;295:C819-27 pubmed publisher
Shen Z, Esnault S, Rosenthal L, Szakaly R, Sorkness R, Westmark P, et al. Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis. J Clin Invest. 2008;118:479-90 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB2294

SKU :

MAB2294

product name :

Human/Mouse Pin1 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse Pin1 Antibody from R&D Systems is a mouse monoclonal antibody to Pin1. This antibody reacts with human,mouse. The Human/Mouse Pin1 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry.

target :

Pin1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

257417

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.5 ug/mL, Immunohistochemistry 8-25 ug/mL, Immunoprecipitation 2-3 ug/500 ug cell lysate, Immunocytochemistry 8-25 ug/mL

host :

Mouse

immunogen :

E. coli -derived recombinant human Pin1, Ala2-Glu163, Accession # Q13526

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human and mouse Pin1 in Western blots.

gene symbol :

PIN1

top caption :

Detection of Human/Mouse Pin1 antibody by Western Blot.

accessionNumbers :

Q13526

applications :

Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry

USD :

469 USD

alt names :

dod, EC 5.2.1.8, peptidyl-prolyl cis/trans isomerase, NIMA-interacting, peptidylprolyl cis/trans isomerase, NIMA-interacting 1, peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, prolyl isomerase, protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1, protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1, Rotamase Pin1, UBL5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage