product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human gp130 Antibody
catalog :
MAB2281-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
29104
reactivity :
human, mouse
application :
western blot, ELISA
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...
Wang H, Hou W, Perera A, Bettler C, Beach J, Ding X, et al. Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling. Cell Rep. 2021;34:108765 pubmed publisher
Karavyraki M, Porter R. Evidence of a role for interleukin-6 in anoikis resistance in oral squamous cell carcinoma. Med Oncol. 2022;39:60 pubmed publisher
Hosokawa Y, Hosokawa I, Ozaki K, Matsuo T. IL-27 Modulates Chemokine Production in TNF-α -Stimulated Human Oral Epithelial Cells. Cell Physiol Biochem. 2017;43:1198-1206 pubmed publisher
Campbell I, Erta M, Lim S, Frausto R, May U, Rose John S, et al. Trans-signaling is a dominant mechanism for the pathogenic actions of interleukin-6 in the brain. J Neurosci. 2014;34:2503-13 pubmed publisher
Ammit A, Moir L, Oliver B, Hughes J, Alkhouri H, Ge Q, et al. Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2007;292:L199-206 pubmed
product information
master code :
MAB2281
SKU :
MAB2281-100
product name :
Human gp130 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human gp130 Antibody from R&D Systems is a mouse monoclonal antibody to gp130/CD130. This antibody reacts with human,mouse. The Human gp130 Antibody has been validated for the following applications: Western Blot,ELISA.
target :
gp130
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
29104
conjugate :
Unconjugated
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human gp130 extracellular domain, Leu24-Glu619 (Glu619Asp), Accession # P40189
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human gp130 in direct ELISAs. In direct ELISAs no cross-reactivity with recombinant mouse gp130 is observed.
gene symbol :
IL6ST
accessionNumbers :
P40189
applications :
Western Blot,ELISA
USD :
459 USD
alt names :
CD130, CD130 antigen, CDw130, DKFZp564F053, gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB, IL-6R-beta, IL6ST, interleukin 6 signal transducer (gp130, oncostatin M receptor), interleukin receptor beta chain, interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, membrane glycoprotein gp130, Oncostatin-M receptor subunit alpha
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.