Human gp130 Antibody | R&D Systems MAB228 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human gp130 Antibody

catalog :

MAB228

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

28126

reactivity :

human

application :

neutralization, flow cytometry

citations: 4

Reference
Wilkinson A, Gartlan K, Kelly G, Samson L, Olver S, Avery J, et al. Granulocytes Are Unresponsive to IL-6 Due to an Absence of gp130. J Immunol. 2018;200:3547-3555 pubmed publisher
Ambarus C, Krausz S, van Eijk M, Hamann J, Radstake T, Reedquist K, et al. Systematic validation of specific phenotypic markers for in vitro polarized human macrophages. J Immunol Methods. 2012;375:196-206 pubmed publisher
Ara T, Song L, Shimada H, Keshelava N, Russell H, Metelitsa L, et al. Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res. 2009;69:329-37 pubmed publisher
Erices A, Conget P, Rojas C, Minguell J. Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells. Exp Cell Res. 2002;280:24-32 pubmed

product information

brand :

R&D Systems

master code :

MAB228

SKU :

MAB228-100

product name :

Human gp130 Antibody

description :

The Human gp130 Antibody from R&D Systems is a mouse monoclonal antibody to gp130/CD130. This antibody reacts with human. The Human gp130 Antibody has been validated for the following applications: Flow Cytometry, Neutralization, CyTOF-ready.

target :

gp130/CD130

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

28126

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human gp130 extracellular domain

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human gp130 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R, rhIL-4 R, or rhIL-6 R is observed.

gene symbol :

IL6ST

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB228

applications :

Flow Cytometry, Neutralization, CyTOF-ready

2020 USD :

339

2021 USD :

359 USD

alt names :

CD130, CD130 antigen, CDw130, DKFZp564F053, gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB, IL-6R-beta, IL6ST, interleukin 6 signal transducer (gp130, oncostatin M receptor), interleukin receptor beta chain, interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, membrane glycoprotein gp130, Oncostatin-M receptor subunit alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.