Human TNF RI/TNFRSF1A Antibody | R&D Systems MAB225-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TNF RI/TNFRSF1A Antibody

catalog :

MAB225-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

16803

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 42

Reference
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Chung C, Kitzler T, Kachurina N, Pessina K, Babayeva S, Bitzan M, et al. Intrinsic tumor necrosis factor-α pathway is activated in a subset of patients with focal segmental glomerulosclerosis. PLoS ONE. 2019;14:e0216426 pubmed publisher
Minshawi F, White M, Muller W, Humphreys N, Jackson D, Campbell B, et al. Human TNF-Luc reporter mouse: A new model to quantify inflammatory responses. Sci Rep. 2019;9:193 pubmed publisher
Monguió Tortajada M, Franquesa M, Sarrias M, Borras F. Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes. Cell Death Dis. 2018;9:499 pubmed publisher
Holdbrooks A, Britain C, Bellis S. ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor. J Biol Chem. 2018;293:1610-1622 pubmed publisher
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Ross S, Sherman M, McElroy P, Lofgren J, Moody G, Baeuerle P, et al. Bispecific T cell engager (BiTE®) antibody constructs can mediate bystander tumor cell killing. PLoS ONE. 2017;12:e0183390 pubmed publisher
Wang X, He Z, Liu H, Yousefi S, Simon H. Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming. J Immunol. 2016;197:4090-4100 pubmed
Morton P, Hicks A, Ortiz Zapater E, Raghavan S, Pike R, Noble A, et al. TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers. Sci Rep. 2016;6:26321 pubmed publisher
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Miller M, Moss M, POWELL G, Petrovich R, Edwards L, Meyer A, et al. Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain. Sci Rep. 2015;5:15150 pubmed publisher
Perotti V, Baldassari P, Molla A, Vegetti C, Bersani I, Maurichi A, et al. NFATc2 is an intrinsic regulator of melanoma dedifferentiation. Oncogene. 2016;35:2862-72 pubmed publisher
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product information

master code :

MAB225

SKU :

MAB225-100

product name :

Human TNF RI/TNFRSF1A Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human TNF RI/TNFRSF1A Antibody from R&D Systems is a mouse monoclonal antibody to TNF RI/TNFRSF1A. This antibody reacts with human,mouse,rat. The Human TNF RI/TNFRSF1A Antibody has been validated for the following applications: Neutralization,Flow Cytometry,Western Blot,Cell Culture,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,CyTOF-ready.

target :

TNF RI/TNFRSF1A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

16803

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human TNF RI/TNFRSF1A, Accession # NP_001056

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human TNF RI in Western blots. In Western blots, does not cross-react with recombinant human (rh) TNF RII, rmTNF RI, or rmTNF RII.

gene symbol :

TNFRSF1A

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

TNF RI/TNFRSF1A Inhibition of TNF-a-induced Cytotoxicity and Neutralization by Human TNF RI/TNFRSF1A Antibody.

accessionNumbers :

NP_001056

applications :

Neutralization,Flow Cytometry,Western Blot,Cell Culture,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,CyTOF-ready

USD :

489 USD

alt names :

CD120a, CD120a antigen, FPF, p55, p55-R, p60, TNFARMGC19588, TNF-R, TNF-R1, TNFR1TBP1, TNFR55, TNF-R55, TNFR60, TNFRI, TNF-RI, TNF-R-I, TNFR-I, TNFRSF1A, tumor necrosis factor binding protein 1, Tumor necrosis factor receptor 1, tumor necrosis factor receptor 1A isoform beta, tumor necrosis factor receptor superfamily member 1A, tumor necrosis factor receptor superfamily, member 1A, tumor necrosis factor receptor type 1, Tumor necrosis factor receptor type I, tumor necrosis factor-alpha receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage