Human NKp44/NCR2 Antibody | R&D Systems MAB22491 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human NKp44/NCR2 Antibody

catalog :

MAB22491

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

253415

reactivity :

human, chimpanzee

application :

neutralization, flow cytometry, mass cytometry

more info or order :

R&D Systems product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
mass cytometry; human; loading ...; fig 2d	Jiang Z, Qin L, Tang Y, Liao R, Shi J, He B, et al. Human induced-T-to-natural killer cells have potent anti-tumour activities. Biomark Res. 2022;10:13 pubmed publisher
	Souza Moreira L, Tan Y, Wang Y, Wang J, Salkhordeh M, Virgo J, et al. Poly(I:C) enhances mesenchymal stem cell control of myeloid cells from COVID-19 patients. iScience. 2022;25:104188 pubmed publisher
	Mayassi T, Ladell K, Gudjonson H, McLaren J, Shaw D, Tran M, et al. Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease. Cell. 2019;176:967-981.e19 pubmed publisher
	Xu X, Narni Mancinelli E, Cantoni C, Li Y, Guia S, Gauthier L, et al. Structural Insights into the Inhibitory Mechanism of an Antibody against B7-H6, a Stress-Induced Cellular Ligand for the Natural Killer Cell Receptor NKp30. J Mol Biol. 2016;428:4457-4466 pubmed publisher
	Fu W, Qin B, Zhou A, Yu Q, Huang Q, Liang Z. Regulation of NK92-MI cell cytotoxicity by substance P. Scand J Immunol. 2011;74:107-13 pubmed publisher
	Hershkovitz O, Rosental B, Rosenberg L, Navarro Sanchez M, Jivov S, Zilka A, et al. NKp44 receptor mediates interaction of the envelope glycoproteins from the West Nile and dengue viruses with NK cells. J Immunol. 2009;183:2610-21 pubmed publisher
	De Maria A, Ugolotti E, Rutjens E, Mazza S, Radic L, Faravelli A, et al. NKp44 expression, phylogenesis and function in non-human primate NK cells. Int Immunol. 2009;21:245-55 pubmed publisher
	Shi J, Tricot G, Garg T, Malaviarachchi P, Szmania S, Kellum R, et al. Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma. Blood. 2008;111:1309-17 pubmed

product information

master code :

MAB22491

SKU :

MAB22491

product name :

Human NKp44/NCR2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human NKp44/NCR2 Antibody from R&D Systems is a mouse monoclonal antibody to NKp44/NCR2. This antibody reacts with human,mouse,primate - pan troglodytes (chimpanzee). The Human NKp44/NCR2 Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Functional Assay,Agonist Activity,CyTOF-reported.

target :

NKp44/NCR2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

253415

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human NKp44/NCR2, Gln22-Pro190, Accession # CAB52289

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Primate - Pan troglodytes (Chimpanzee)

specificity :

Detects human NKp44/NCR2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) NKp30, rhNKp46, rhNKp80, or recombinant mouse NKp46 is observed.

gene symbol :

NCR2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Human NKp44/NCR2 Antibody Induces IFN-? Secretion antibody in Activated Human NK Cells.

accessionNumbers :

CAB52289

applications :

Flow Cytometry,Neutralization,Functional Assay,Agonist Activity,CyTOF-reported

USD :

469 USD

alt names :

CD336, CD336 antigen, LY95, LY95lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44), lymphocyte antigen 95 (activating NK-receptor; NK-p44), Lymphocyte antigen 95 homolog, natural cytotoxicity triggering receptor 2, Natural killer cell p44-related protein, NCR2, NK cell activating receptor (NKp44), NK cell-activating receptor, NKP44, NK-p44dJ149M18.1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage