product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-2 R▀ Antibody
catalog :
MAB224-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
27302
reactivity :
human, rhesus macaque
application :
immunohistochemistry, neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 7
Reference
Wu W, Shiu C, Tong T, LEUNG S, Hui C. Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases. J Immunol Res. 2023;2023:8924603 pubmed publisher
Shankar S, Stolp J, Juvet S, Beckett J, Macklin P, Issa F, et al. Ex vivo-expanded human CD19+TIM-1+ regulatory B cells suppress immune responses in vivo and are dependent upon the TIM-1/STAT3 axis. Nat Commun. 2022;13:3121 pubmed publisher
Jiang J, Chen X, An H, Yang B, Zhang F, Cheng X. Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling. Sci Rep. 2016;6:32320 pubmed publisher
Ndhlovu L, Leal F, Eccles James I, Jha A, Lanteri M, Norris P, et al. A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties. Eur J Immunol. 2010;40:134-41 pubmed publisher
Rose T, Lambotte O, Pallier C, Delfraissy J, Colle J. Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients. J Immunol. 2009;182:7389-97 pubmed publisher
Eberly M, Kader M, Hassan W, Rogers K, Zhou J, Mueller Y, et al. Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection. J Immunol. 2009;182:1439-48 pubmed
Miranda Carús M, Balsa A, Benito Miguel M, Pérez de Ayala C, Martin Mola E. IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate. J Immunol. 2004;173:1463-76 pubmed
product information
master code :
MAB224
SKU :
MAB224-100
product name :
Human IL-2 R▀ Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human IL-2 Rß Antibody from R&D Systems is a mouse monoclonal antibody to IL-2 R beta. This antibody reacts with human,primate - macaca mulatta (rhesus macaque). The Human IL-2 Rß Antibody has been validated for the following applications: Protein Array,ELISA Development,Flow Cytometry,Neutralization,Immunohistochemistry,CyTOF-ready.
target :
IL-2 R beta
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
27302
conjugate :
Unconjugated
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-2 R▀, Ala27-Asp239, Accession # NP_000869
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human,Primate - Macaca mulatta (Rhesus Macaque)
specificity :
Detects human IL-2 R▀ in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha , rh gamma c, rhIL-4 R, or rhIL-6 R is observed.
gene symbol :
IL2RB
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
IL-2 Rss antibody in Human Lymph Node by Immunohistochemistry (IHC-Fr).
accessionNumbers :
NP_000869
applications :
Protein Array,ELISA Development,Flow Cytometry,Neutralization,Immunohistochemistry,CyTOF-ready
USD :
499 USD
alt names :
CD122, CD122 antigen, high affinity IL-2 receptor beta subunit, High affinity IL-2 receptor subunit beta, IL-15 R beta, IL-2 receptor subunit beta, IL2R beta, IL-2R subunit beta, IL2RB, IL-2RB, interleukin 15 receptor, beta, interleukin 2 receptor, beta, interleukin-2 receptor subunit beta, P70-75, p75
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.