product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human KIR2DL4/CD158d Antibody
catalog :
MAB2238
quantity :
500 ug (also 25 ug)
price :
569 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
181703
reactivity :
human
application :
immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 9
Reference
Mkorombindo T, Tran Nguyen T, Yuan K, Zhang Y, Xue J, Criner G, et al. HLA-C and KIR permutations influence chronic obstructive pulmonary disease risk. JCI Insight. 2021;6: pubmed publisher
Ueshima C, Kataoka T, Hirata M, Sugimoto A, Iemura Y, Minamiguchi S, et al. Possible Involvement of Human Mast Cells in the Establishment of Pregnancy via Killer Cell Ig-Like Receptor 2DL4. Am J Pathol. 2018;188:1497-1508 pubmed publisher
York A, Zheng J. Super-Resolution Microscopy Reveals a Nanoscale Organization of Acetylcholine Receptors for Trans-Synaptic Alignment at Neuromuscular Synapses. Eneuro. 2017;4: pubmed publisher
Takei Y, Ueshima C, Kataoka T, Hirata M, Sugimoto A, Rokutan Kurata M, et al. Killer cell immunoglobulin-like receptor 2DL4 is expressed in and suppresses the cell growth of Langerhans cell histiocytosis. Oncotarget. 2017;8:36964-36972 pubmed publisher
Kennedy P, Chazara O, Gardner L, Ivarsson M, Farrell L, Xiong S, et al. Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy. J Immunol. 2016;197:4292-4300 pubmed
Rajagopalan S, Lee E, Duprie M, Long E. TNFR-associated factor 6 and TGF-β-activated kinase 1 control signals for a senescence response by an endosomal NK cell receptor. J Immunol. 2014;192:714-21 pubmed publisher
Le Page M, Goodridge J, John E, Christiansen F, Witt C. Killer Ig-like receptor 2DL4 does not mediate NK cell IFN-? responses to soluble HLA-G preparations. J Immunol. 2014;192:732-40 pubmed publisher
Siewiera J, El Costa H, Tabiasco J, Berrebi A, Cartron G, Le Bouteiller P, et al. Human cytomegalovirus infection elicits new decidual natural killer cell effector functions. PLoS Pathog. 2013;9:e1003257 pubmed publisher
Esin S, Batoni G, Counoupas C, Stringaro A, Brancatisano F, Colone M, et al. Direct binding of human NK cell natural cytotoxicity receptor NKp44 to the surfaces of mycobacteria and other bacteria. Infect Immun. 2008;76:1719-27 pubmed publisher
product information
master code :
MAB2238
SKU :
MAB2238
product name :
Human KIR2DL4/CD158d Antibody
unit size :
500 ug (also 25 ug)
description :
The Human KIR2DL4/CD158d Antibody from R&D Systems is a mouse monoclonal antibody to KIR2DL4/CD158d. This antibody reacts with human. The Human KIR2DL4/CD158d Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Functional Assay,Immunocytochemistry,Agonist Activity,CyTOF-reported.
target :
KIR2DL4/CD158d
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
181703
conjugate :
Unconjugated
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human KIR2DL4/CD158d, Accession # Q99706
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Stains human KIR2DL4/CD158d transfected BaF/3 cells. It does not recognize transfectants that express KIR2DL1, 2DL2, 2DL3, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
gene symbol :
KIR2DL4
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
accessionNumbers :
Q99706
applications :
Flow Cytometry,Immunoprecipitation,Functional Assay,Immunocytochemistry,Agonist Activity,CyTOF-reported
USD :
569 USD
alt names :
103AS, 15.212, CD158 antigen-like family member D, CD158d, CD158d antigen, CD158DKIR103ASKiller cell inhibitory receptor 103AS, G9P, killer cell immunoglobulin-like receptor 2DL4, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4, killer Ig receptor, KIR103, KIR-103AS, MHC class I NK cell receptor KIR103AS, natural killer cell inhibitory receptor, NK cell receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.