Human CD25/IL-2R alpha Antibody | R&D Systems MAB223-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD25/IL-2R alpha Antibody

catalog :

MAB223-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

22722

reactivity :

human

application :

western blot, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Reference
Sigutova V, Xiang W, Regensburger M, Winner B, Prots I. Alpha-synuclein fine-tunes neuronal response to pro-inflammatory cytokines. Brain Behav Immun. 2024;122:216-230 pubmed publisher
Wu W, Shiu C, Tong T, LEUNG S, Hui C. Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases. J Immunol Res. 2023;2023:8924603 pubmed publisher
Shankar S, Stolp J, Juvet S, Beckett J, Macklin P, Issa F, et al. Ex vivo-expanded human CD19+TIM-1+ regulatory B cells suppress immune responses in vivo and are dependent upon the TIM-1/STAT3 axis. Nat Commun. 2022;13:3121 pubmed publisher
Ho T, Pfeffer K, Weiss G, Ruiz Y, Lake D. Identification of a CD4+ T cell line with Treg-like activity. Hum Immunol. 2022;83:281-294 pubmed publisher
Faridar A, Thome A, Zhao W, Thonhoff J, Beers D, Pascual B, et al. Restoring regulatory T-cell dysfunction in Alzheimer's disease through ex vivo expansion. Brain Commun. 2020;2:fcaa112 pubmed publisher
Porichis F, Hart M, Massa A, Everett H, Morou A, Richard J, et al. Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells. J Immunol. 2018;201:971-981 pubmed publisher
Jiang J, Chen X, An H, Yang B, Zhang F, Cheng X. Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling. Sci Rep. 2016;6:32320 pubmed publisher
Oas R, Nanes B, Esimai C, Vincent P, Garcia A, Kowalczyk A. p120-catenin and ?-catenin differentially regulate cadherin adhesive function. Mol Biol Cell. 2013;24:704-14 pubmed publisher
Bhatt S, Zalcman S, Hassanain M, Siegel A. Cytokine modulation of defensive rage behavior in the cat: role of GABAA and interleukin-2 receptors in the medial hypothalamus. Neuroscience. 2005;133:17-28 pubmed

product information

master code :

MAB223

SKU :

MAB223-100

product name :

Human CD25/IL-2R alpha Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CD25/IL-2R alpha Antibody from R&D Systems is a mouse monoclonal antibody to CD25/IL-2R alpha. This antibody reacts with feline,human. The Human CD25/IL-2R alpha Antibody has been validated for the following applications: Bioassay,Flow Cytometry,Neutralization,Western Blot,Immunocytochemistry.

target :

CD25/IL-2R alpha

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

22722

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD25/IL-2 R alpha , Glu22-Cys213, Accession # P01589

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Feline,Human

specificity :

Detects human CD25/IL-2 R alpha in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 4% cross-reactivity with recombinant human (rh) IL-2 R▀ is observed and no cross-reactivity with rhIL-2 R gamma , rhIL-1 RI, rhIL-1 RII, rhIL-4 R, rhIL-5 R alpha , rhIL-6 R, rhIL-7 R, rhIL-9 R, and rhIL-10 R is observed.

gene symbol :

IL2RA

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

CD25/IL-2 Ra antibody in Human PBMCs by Immunocytochemistry (ICC).

accessionNumbers :

P01589

applications :

Bioassay,Flow Cytometry,Neutralization,Western Blot,Immunocytochemistry

USD :

469 USD

alt names :

CD25, CD25 antigen, IDDM10, IL-2 R alpha, IL-2 receptor subunit alpha, IL2R, IL2R alpha, IL-2R subunit alpha, IL-2Ra, IL2RA, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage