product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Carbonic Anhydrase IV/CA4 Antibody
catalog :
MAB2186
quantity :
100 ug (also 25 ug)
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
310413
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 5
Reference
Okamoto S, Yasuda M, Kawaguchi K, Yasuoka K, Kikukawa Y, Asano S, et al. Ciliary Motility Decreased by a CO2/HCO3--Free Solution in Ciliated Human Nasal Epithelial Cells Having a pH Elevated by Carbonic Anhydrase IV. Int J Mol Sci. 2024;25: pubmed publisher
Forero Quintero L, Ames S, Schneider H, Thyssen A, Boone C, Andring J, et al. Membrane-anchored carbonic anhydrase IV interacts with monocarboxylate transporters via their chaperones CD147 and GP70. J Biol Chem. 2019;294:593-607 pubmed publisher
Klier M, Andes F, Deitmer J, Becker H. Intracellular and extracellular carbonic anhydrases cooperate non-enzymatically to enhance activity of monocarboxylate transporters. J Biol Chem. 2014;289:2765-75 pubmed publisher
Klier M, Schüler C, Halestrap A, Sly W, Deitmer J, Becker H. Transport activity of the high-affinity monocarboxylate transporter MCT2 is enhanced by extracellular carbonic anhydrase IV but not by intracellular carbonic anhydrase II. J Biol Chem. 2011;286:27781-91 pubmed publisher
Shahidullah M, To C, Pelis R, Delamere N. Studies on bicarbonate transporters and carbonic anhydrase in porcine nonpigmented ciliary epithelium. Invest Ophthalmol Vis Sci. 2009;50:1791-800 pubmed publisher
product information
master code :
MAB2186
SKU :
MAB2186
product name :
Human Carbonic Anhydrase IV/CA4 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Carbonic Anhydrase IV/CA4 Antibody from R&D Systems is a mouse monoclonal antibody to Carbonic Anhydrase IV/CA4. This antibody reacts with amphibian,human,porcine,frog - xenopus (african clawed frog). The Human Carbonic Anhydrase IV/CA4 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunohistochemistry,Immunoprecipitation.
target :
Carbonic Anhydrase IV/CA4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
310413
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Carbonic Anhydrase IV/CA4, Ala19-Lys283, Accession # P22748
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Amphibian,Human,Porcine,Frog - Xenopus (African Clawed Frog)
specificity :
Detects human Carbonic Anhydrase IV/CA4 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant human (rh) CA1, rhCA2, and recombinant mouse CA4 is observed. Does not cross-react with rhCA3, 8, 9, 10, 12, 13, or 14.
gene symbol :
CA4
top caption :
Detection of Human Carbonic Anhydrase IV/CA4 antibody by Western Blot.
accessionNumbers :
P22748
applications :
Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunohistochemistry,Immunoprecipitation
USD :
439 USD
alt names :
CA4, CAIV, CA-IV, Car4, Carbonate dehydratase IV, carbonic anhydrase 4, carbonic anhydrase IVRP17, carbonic dehydratase IV, EC 4.2.1.1, retinitis pigmentosa 17 (autosomal dominant), RP17
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.