Human IL-10 Antibody | R&D Systems MAB2172 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-10 Antibody

catalog :

MAB2172

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

127107

reactivity :

human

application :

western blot, ELISA, flow cytometry

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 5c	Piancone F, Saresella M, Marventano I, La Rosa F, Zoppis M, Agostini S, et al. B Lymphocytes in Multiple Sclerosis: Bregs and BTLA/CD272 Expressing-CD19+ Lymphocytes Modulate Disease Severity. Sci Rep. 2016;6:29699 pubmed publisher
	Stumpf A, Brandstetter T, Hübner J, Rühe J. Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum. PLoS ONE. 2019;14:e0225525 pubmed publisher
	Brencicova E, Jagger A, Evans H, Georgouli M, Laios A, Attard Montalto S, et al. Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma. PLoS ONE. 2017;12:e0175712 pubmed publisher
	Heo Y, Joo Y, Oh H, Park M, Heo Y, Cho M, et al. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients. Immunol Lett. 2010;127:150-6 pubmed publisher
	Grivel J, Elliott J, Lisco A, Biancotto A, Condack C, Shattock R, et al. HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1. AIDS. 2007;21:1263-72 pubmed
	Du Z, Kelly E, Mecklenbrauker I, Agle L, Herrero C, Paik P, et al. Selective regulation of IL-10 signaling and function by zymosan. J Immunol. 2006;176:4785-92 pubmed
	Copeland S, Siddiqui J, Remick D. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J Immunol Methods. 2004;284:99-106 pubmed

product information

brand :

R&D Systems

master code :

MAB2172

SKU :

MAB2172-100

product name :

Human IL-10 Antibody

description :

The Human IL-10 Antibody from R&D Systems is a mouse monoclonal antibody to IL-10. This antibody reacts with human. The Human IL-10 Antibody has been validated for the following applications: Western Blot, ELISA Capture (Matched Antibody Pair).

target :

IL-10

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

127107

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-10, Ser19-Asn178, Accession # P22301

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IL-10 in ELISAs. In sandwich immunoassays, less than 5% cross-reactivity with recombinant equine IL-10 is observed and less than 0.5% cross-reactivity with recombinant canine IL-10, recombinant mouse IL-10, recombinant rat IL-10, recombinant porcine IL-10, recombinant cotton rat IL-10, and recombinant feline IL-10 is observed.

gene symbol :

IL10

catalog number base :

MAB2172

accessionNumbers :

P22301

applications :

Western Blot, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.