Human IL-10 Antibody | R&D Systems MAB2172-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-10 Antibody

catalog :

MAB2172-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

127107

reactivity :

human

application :

western blot, ELISA, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 8

Reference
Chin L, Yang J, Chousterman B, Jung S, Kim D, Kim D, et al. Dual-Enhanced Plasmonic Biosensing for Point-of-Care Sepsis Detection. ACS Nano. 2023;17:3610-3619 pubmed publisher
Stumpf A, Brandstetter T, Hübner J, Rühe J. Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum. PLoS ONE. 2019;14:e0225525 pubmed publisher
Brencicova E, Jagger A, Evans H, Georgouli M, Laios A, Attard Montalto S, et al. Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma. PLoS ONE. 2017;12:e0175712 pubmed publisher
Valentina M, Jan F, Peder N, Bo Z, Hongjie D, Pernille K. Cytokine detection and simultaneous assessment of rheumatoid factor interference in human serum and synovial fluid using high-sensitivity protein arrays on plasmonic gold chips. BMC Biotechnol. 2015;15:73 pubmed publisher
Heo Y, Joo Y, Oh H, Park M, Heo Y, Cho M, et al. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients. Immunol Lett. 2010;127:150-6 pubmed publisher
Grivel J, Elliott J, Lisco A, Biancotto A, Condack C, Shattock R, et al. HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1. AIDS. 2007;21:1263-72 pubmed
Du Z, Kelly E, Mecklenbrauker I, Agle L, Herrero C, Paik P, et al. Selective regulation of IL-10 signaling and function by zymosan. J Immunol. 2006;176:4785-92 pubmed
Copeland S, Siddiqui J, Remick D. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J Immunol Methods. 2004;284:99-106 pubmed

product information

brand :

R&D Systems

master code :

MAB2172

SKU :

MAB2172-100

product name :

Human IL-10 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human IL-10 Antibody from R&D Systems is a mouse monoclonal antibody to IL-10. This antibody reacts with human. The Human IL-10 Antibody has been validated for the following applications: Array Development,ELISA Development,ELISA Development (Capture),ELISA Capture,Immunohistochemistry-Paraffin,Western Blot,ELISA Capture (Matched Antibody Pair).

target :

IL-10

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

127107

conjugate :

Unconjugated

dilution :

Western Blot 5 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-10, Ser19-Asn178, Accession # P22301

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IL-10 in ELISAs. In sandwich immunoassays, less than 5% cross-reactivity with recombinant equine IL-10 is observed and less than 0.5% cross-reactivity with recombinant canine IL-10, recombinant mouse IL-10, recombinant rat IL-10, recombinant porcine IL-10, recombinant cotton rat IL-10, and recombinant feline IL-10 is observed.

gene symbol :

IL10

top caption :

Detection of Human IL-10 antibody by Western Blot.

accessionNumbers :

P22301

applications :

Western Blot,ELISA Capture (Matched Antibody Pair),Array Development,ELISA Development,ELISA Development (Capture),Immunohistochemistry-Paraffin,ELISA Capture

USD :

499 USD

alt names :

CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage