Human IL-10 Antibody | R&D Systems MAB2171-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-10 Antibody

catalog :

MAB2171-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

25209

reactivity :

human, mouse

application :

western blot, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 17

Reference
von Glehn F, Pochet N, Thapa B, Raheja R, Mazzola M, Jangi S, et al. Defective Induction of IL-27-Mediated Immunoregulation by Myeloid DCs in Multiple Sclerosis. Int J Mol Sci. 2023;24: pubmed publisher
Shokri M, Bozorgmehr M, Ghanavatinejad A, Falak R, Aleahmad M, Kazemnejad S, et al. Human menstrual blood-derived stromal/stem cells modulate functional features of natural killer cells. Sci Rep. 2019;9:10007 pubmed publisher
Song H, Tan G, Yang Y, Cui A, Li H, Li T, et al. Hepatitis B Virus-Induced Imbalance of Inflammatory and Antiviral Signaling by Differential Phosphorylation of STAT1 in Human Monocytes. J Immunol. 2019;202:2266-2275 pubmed publisher
Tzach Nahman R, Nashef R, Fleissig O, Palmon A, Shapira L, Wilensky A, et al. Oral fibroblasts modulate the macrophage response to bacterial challenge. Sci Rep. 2017;7:11516 pubmed publisher
Nakachi S, Sumitomo S, Tsuchida Y, Tsuchiya H, Kono M, Kato R, et al. Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis. Arthritis Res Ther. 2017;19:97 pubmed publisher
Fontaine M, Planel S, Peronnet E, Turrel Davin F, Piriou V, Pachot A, et al. S100A8/A9 mRNA induction in an ex vivo model of endotoxin tolerance: roles of IL-10 and IFN?. PLoS ONE. 2014;9:e100909 pubmed publisher
Planès R, BenMohamed L, Leghmari K, Delobel P, Izopet J, Bahraoui E. HIV-1 Tat protein induces PD-L1 (B7-H1) expression on dendritic cells through tumor necrosis factor alpha- and toll-like receptor 4-mediated mechanisms. J Virol. 2014;88:6672-89 pubmed publisher
Svajger U, Obermajer N, Jeras M. IFN-?-rich environment programs dendritic cells toward silencing of cytotoxic immune responses. J Leukoc Biol. 2014;95:33-46 pubmed publisher
Wang Y, Sung W, Wu T, Wang L, Chien W, Cheng Y, et al. Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer. PLoS ONE. 2012;7:e39525 pubmed publisher
Nicolaidou V, Wong M, Redpath A, Ersek A, Baban D, Williams L, et al. Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation. PLoS ONE. 2012;7:e39871 pubmed publisher
Svajger U, Obermajer N, Anderluh M, Kos J, Jeras M. DC-SIGN ligation greatly affects dendritic cell differentiation from monocytes compromising their normal function. J Leukoc Biol. 2011;89:893-905 pubmed publisher
Chusid L, Pereira Argenziano L, Miskolci V, Vancurova I, Davidson D. Transcriptional control of cytokine release from monocytes of the newborn: effects of endogenous and exogenous interleukin-10 versus dexamethasone. Neonatology. 2010;97:108-16 pubmed publisher
Tran D, Glass D, Uzel G, Darnell D, Spalding C, Holland S, et al. Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function. J Immunol. 2009;182:2929-38 pubmed publisher
Liu T, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, et al. Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells. Eur J Immunol. 2008;38:1012-23 pubmed publisher
Hajishengallis G, Shakhatreh M, Wang M, Liang S. Complement receptor 3 blockade promotes IL-12-mediated clearance of Porphyromonas gingivalis and negates its virulence in vivo. J Immunol. 2007;179:2359-67 pubmed
Nylen S, Maurya R, Eidsmo L, Manandhar K, Sundar S, Sacks D. Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis. J Exp Med. 2007;204:805-17 pubmed
Perez S, Mahaira L, Sotiropoulou P, Gritzapis A, Iliopoulou E, Niarchos D, et al. Effect of IL-21 on NK cells derived from different umbilical cord blood populations. Int Immunol. 2006;18:49-58 pubmed

product information

brand :

R&D Systems

master code :

MAB2171

SKU :

MAB2171-100

product name :

Human IL-10 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human IL-10 Antibody from R&D Systems is a mouse monoclonal antibody to IL-10. This antibody reacts with human,mouse. The Human IL-10 Antibody has been validated for the following applications: Bioassay,Flow Cytometry,Neutralization,Western Blot.

target :

IL-10

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

25209

conjugate :

Unconjugated

dilution :

Western Blot 5 ug/mL, Neutralization 0.005-0.03 ug/mL

host :

Mouse

immunogen :

E. coli -derived recombinant human IL-10, Ser19-Asn178, Accession # P22301

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human,Mouse

specificity :

Detects human IL-10 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse IL-10.

gene symbol :

IL10

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Human IL-10 antibody by Western Blot.

accessionNumbers :

P22301

applications :

Western Blot,Bioassay,Flow Cytometry,Neutralization

USD :

479 USD

alt names :

CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage