Mouse Complement Component C5a Antibody | R&D Systems MAB21501-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Complement Component C5a Antibody

catalog :

MAB21501-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

295108

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 4

Reference
Llori xe1 n Salvador M, Byrne E, Szczepan M, Little K, Chen M, Xu H. Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells. J Neuroinflammation. 2022;19:182 pubmed publisher
Sun D, Zhang M, Liu G, Wu H, Zhu X, Zhou H, et al. Real-Time Imaging of Interactions of Neutrophils with Cryptococcus neoformans Demonstrates a Crucial Role of Complement C5a-C5aR Signaling. Infect Immun. 2016;84:216-29 pubmed publisher
Price P, BÃ¡nki Z, Scheideler A, Stoiber H, Verschoor A, Sutter G, et al. Complement component C5 recruits neutrophils in the absence of C3 during respiratory infection with modified vaccinia virus Ankara. J Immunol. 2015;194:1164-8 pubmed publisher
Kim J, Oh S, Ahn S, Chung D. IFN-?-producing NKT cells exacerbate sepsis by enhancing C5a generation via IL-10-mediated inhibition of CD55 expression on neutrophils. Eur J Immunol. 2014;44:2025-35 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB21501

SKU :

MAB21501-100

product name :

Mouse Complement Component C5a Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Mouse Complement Component C5a Antibody from R&D Systems is a rat monoclonal antibody to Complement Component C5a. This antibody reacts with mouse. The Mouse Complement Component C5a Antibody has been validated for the following applications: Inhibition,Western Blot,Neutralization,Immunocytochemistry,ELISA Capture (Matched Antibody Pair).

target :

Complement Component C5a

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

295108

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Neutralization 0.1-0.5 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL

host :

Rat

immunogen :

E. coli -derived recombinant mouse Complement Component C5a, Asn679-Arg755, Accession # P06684

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse Complement Component C5a in Western blots. In Western blots, this antibody does not cross-react with recombinant mouse Complement Component C3d, recombinant human (rh) Complement Component C3a, or rhComplement Component C5a.

gene symbol :

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

N-Acetyl-ss-D-Glucosaminidase Release Induced by Complement Component C5a and Neutralization by Mouse Complement Component C5a Antibody.

accessionNumbers :

P06684

applications :

ELISA Capture (Matched Antibody Pair),Inhibition,Western Blot,Neutralization,Immunocytochemistry

USD :

459 USD

alt names :

C5, C5A, HE

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage