Human GM-CSF Antibody | R&D Systems MAB215-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human GM-CSF Antibody

catalog :

MAB215-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3209

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 25

Reference
Zheng N, Fang J, Xue G, Wang Z, Li X, Zhou M, et al. Induction of tumor cell autosis by myxoma virus-infected CAR-T and TCR-T cells to overcome primary and acquired resistance. Cancer Cell. 2022;40:973-985.e7 pubmed publisher
Ware M, Zaidi M, Yang J, Turgeon M, Krasinskas A, Mace T, et al. Suppressive myeloid cells are expanded by biliary tract cancer-derived cytokines in vitro and associate with aggressive disease. Br J Cancer. 2020;123:1377-1386 pubmed publisher
Ma R, Martínez Ramírez A, Borders T, Gao F, Sosa Pineda B. Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts. elife. 2020;9: pubmed publisher
Ashander L, Lie S, Ma Y, Rochet E, Washington J, Furtado J, et al. Neutrophil Activities in Human Ocular Toxoplasmosis: An In Vitro Study With Human Cells. Invest Ophthalmol Vis Sci. 2019;60:4652-4660 pubmed publisher
Logue S, McGrath E, Cleary P, Greene S, Mnich K, Almanza A, et al. Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy. Nat Commun. 2018;9:3267 pubmed publisher
Gril B, Paranjape A, Woditschka S, Hua E, Dolan E, Hanson J, et al. Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases. Nat Commun. 2018;9:2705 pubmed publisher
Lehr S, Vier J, Hacker G, Kirschnek S. Activation of neutrophils by Chlamydia trachomatis-infected epithelial cells is modulated by the chlamydial plasmid. Microbes Infect. 2018;20:284-292 pubmed publisher
Huang D, Song S, Wu Z, Wu W, Cui X, Chen J, et al. Epstein-Barr Virus-Induced VEGF and GM-CSF Drive Nasopharyngeal Carcinoma Metastasis via Recruitment and Activation of Macrophages. Cancer Res. 2017;77:3591-3604 pubmed publisher
Wood L, Cox N, Phelps C, Lai S, Poddar A, Talbot C, et al. Thyroid Transcription Factor 1 Reprograms Angiogenic Activities of Secretome. Sci Rep. 2016;6:19857 pubmed publisher
Spampinato S, Obermeier B, Cotleur A, Love A, Takeshita Y, Sano Y, et al. Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?. PLoS ONE. 2015;10:e0133392 pubmed publisher
Vogel D, Kooij G, Heijnen P, Breur M, Peferoen L, van der Valk P, et al. GM-CSF promotes migration of human monocytes across the blood brain barrier. Eur J Immunol. 2015;45:1808-19 pubmed publisher
Su S, Liu Q, Chen J, Chen J, Chen F, He C, et al. A positive feedback loop between mesenchymal-like cancer cells and macrophages is essential to breast cancer metastasis. Cancer Cell. 2014;25:605-20 pubmed publisher
Weber G, Chousterman B, Hilgendorf I, Robbins C, Theurl I, Gerhardt L, et al. Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis. J Exp Med. 2014;211:1243-56 pubmed publisher
Levescot A, Flamant S, Basbous S, Jacomet F, Feraud O, Anne Bourgeois E, et al. BCR-ABL-induced deregulation of the IL-33/ST2 pathway in CD34+ progenitors from chronic myeloid leukemia patients. Cancer Res. 2014;74:2669-76 pubmed publisher
Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
Gutschalk C, Yanamandra A, Linde N, Meides A, Depner S, Mueller M. GM-CSF enhances tumor invasion by elevated MMP-2, -9, and -26 expression. Cancer Med. 2013;2:117-29 pubmed publisher
Fu J, Sha B, Thomas L. HIV-1-infected peripheral blood mononuclear cells enhance neutrophil survival and HLA-DR expression via increased production of GM-CSF: implications for HIV-1 infection. J Acquir Immune Defic Syndr. 2011;56:16-25 pubmed publisher
Huang S, Zenclussen A, Chen C, Basar M, Yang H, Arcuri F, et al. The implication of aberrant GM-CSF expression in decidual cells in the pathogenesis of preeclampsia. Am J Pathol. 2010;177:2472-82 pubmed publisher
Choi W, Miyamura Y, Wolber R, Smuda C, Reinhold W, Liu H, et al. Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB. J Invest Dermatol. 2010;130:1685-96 pubmed publisher
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Xiao T, Fujita H, Saeki H, Mitsui H, Sugaya M, Tada Y, et al. Thymus and activation-regulated chemokine (TARC/CCL17) produced by mouse epidermal Langerhans cells is upregulated by TNF-alpha and IL-4 and downregulated by IFN-gamma. Cytokine. 2003;23:126-32 pubmed
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product information

master code :

MAB215

SKU :

MAB215-100

product name :

Human GM-CSF Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human GM-CSF Antibody from R&D Systems is a mouse monoclonal antibody to GM-CSF. This antibody reacts with human,mouse. The Human GM-CSF Antibody has been validated for the following applications: Immunodepletion,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Western Blot,Immunocytochemistry.

target :

GM-CSF

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

3209

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human GM-CSF, Ala18-Glu144, Accession # P04141

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human GM-CSF in Western blots.

gene symbol :

CSF2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

GMCSF antibody in Human PBMCs by Immunocytochemistry (ICC).

accessionNumbers :

P04141

applications :

Immunodepletion,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Western Blot,Immunocytochemistry

USD :

499 USD

alt names :

colony stimulating factor 2 (granulocyte-macrophage), Colony-stimulating factor, CSF, CSF2, CSF-2, GMCSF, GM-CSF, GMCSFgranulocyte-macrophage colony-stimulating factor, granulocyte-macrophage colony stimulating factor, MGC131935, MGC138897, Molgramostim, molgramostin, sargramostim

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage