Tenascin C Antibody | R&D Systems MAB2138 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Tenascin C Antibody

catalog :

MAB2138

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

578

reactivity :

human, mouse

application :

western blot, immunocytochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 16

Reference
Xue Y, Lyu C, Taylor A, Van Ee A, Kiemen A, Choi Y, et al. Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth. Sci Adv. 2022;8:eabl8698 pubmed publisher
Cheng H, M xf6 rbe U, L xfc tge M, Engetschwiler C, Onder L, Novković M, et al. Intestinal fibroblastic reticular cell niches control innate lymphoid cell homeostasis and function. Nat Commun. 2022;13:2027 pubmed publisher
Bernasconi R, Thriene K, Romero Fernández E, Gretzmeier C, Kühl T, Maler M, et al. Pro-inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang-(1-7). EMBO Mol Med. 2021;13:e14392 pubmed publisher
Io S, Kabata M, Iemura Y, Semi K, Morone N, Minagawa A, et al. Capturing human trophoblast development with naive pluripotent stem cells in vitro. Cell Stem Cell. 2021;28:1023-1039.e13 pubmed publisher
Takeo M, Asakawa K, Toyoshima K, Ogawa M, Tong J, Irie T, et al. Expansion and characterization of epithelial stem cells with potential for cyclical hair regeneration. Sci Rep. 2021;11:1173 pubmed publisher
Li Z, Zhang H, Huang Y, Huang J, Sun P, Zhou N, et al. Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation. Nat Commun. 2020;11:3806 pubmed publisher
Ohki S, Oka K, Ogata K, Okuhara S, Rikitake M, Toda Nakamura M, et al. Transforming Growth Factor-Beta and Sonic Hedgehog Signaling in Palatal Epithelium Regulate Tenascin-C Expression in Palatal Mesenchyme During Soft Palate Development. Front Physiol. 2020;11:532 pubmed publisher
Menon R, Otto E, Kokoruda A, Zhou J, Zhang Z, Yoon E, et al. Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney. Development. 2018;145: pubmed publisher
Procopio M, László C, Al Labban D, Kim D, Bordignon P, Jo S, et al. Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation. Nat Cell Biol. 2015;17:1193-204 pubmed publisher
Harada M, Kamimura D, Arima Y, Kohsaka H, Nakatsuji Y, Nishida M, et al. Temporal expression of growth factors triggered by epiregulin regulates inflammation development. J Immunol. 2015;194:1039-46 pubmed publisher
Has C, Kiritsi D, Mellerio J, Franzke C, Wedgeworth E, Tantcheva Poor I, et al. The missense mutation p.R1303Q in type XVII collagen underlies junctional epidermolysis bullosa resembling Kindler syndrome. J Invest Dermatol. 2014;134:845-849 pubmed publisher
Grahovac J, Becker D, Wells A. Melanoma cell invasiveness is promoted at least in part by the epidermal growth factor-like repeats of tenascin-C. J Invest Dermatol. 2013;133:210-20 pubmed publisher
Kern J, Loeckermann S, Fritsch A, Hausser I, Roth W, Magin T, et al. Mechanisms of fibroblast cell therapy for dystrophic epidermolysis bullosa: high stability of collagen VII favors long-term skin integrity. Mol Ther. 2009;17:1605-15 pubmed publisher
Yates C, Whaley D, Y Chen A, Kulesekaran P, Hebda P, Wells A. ELR-negative CXC chemokine CXCL11 (IP-9/I-TAC) facilitates dermal and epidermal maturation during wound repair. Am J Pathol. 2008;173:643-52 pubmed publisher
Fritsch A, Loeckermann S, Kern J, Braun A, Bösl M, Bley T, et al. A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy. J Clin Invest. 2008;118:1669-79 pubmed publisher
Bujak M, Ren G, Kweon H, Dobaczewski M, Reddy A, Taffet G, et al. Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling. Circulation. 2007;116:2127-38 pubmed

image

image 1 :

Tenascin C antibody in U-118 MG Human Cell Line by Immunocytochemistry (ICC).

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB2138

SKU :

MAB2138

product name :

Tenascin C Antibody

Description :

The Human/Mouse Tenascin C Antibody from R&D Systems is a rat monoclonal antibody to Tenascin C. This antibody reacts with human, mouse. The Human/Mouse Tenascin C Antibody has been validated for the following applications: Western Blot, Neutralization, Immunocytochemistry.

target :

Tenascin C

category :

Primary Antibodies

unit size :

100 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

578

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse immature astrocyte-derived Tenascin C

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human, Mouse

specificity :

Detect human and mouse Tenascin C in Western blots.

gene symbol :

TNC

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

applications :

Western Blot, Neutralization, Immunocytochemistry

USD :

489 USD

alt names :

150-225, Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion, hexabrachion (tenascin C, cytotactin), hexabrachion (tenascin), HXB, HXBcytotactin, JI, MGC167029, Myotendinous antigen, neuronectin, tenascin, tenascin C, Tenascin J1, Tenascin-C, tenascin-C isoform 14/AD1/16, TNC, TN-C, TNGP

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage