This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse Tenascin C Antibody
catalog :
MAB2138-SP
quantity :
25 ug
price :
135 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
578
reactivity :
human, mouse
application :
western blot, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, other
citations: 12
Published Application/Species/Sample/DilutionReference
  • other; mouse; loading ...
Li Z, Zhang H, Huang Y, Huang J, Sun P, Zhou N, et al. Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation. Nat Commun. 2020;11:3806 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1b
Ohki S, Oka K, Ogata K, Okuhara S, Rikitake M, Toda Nakamura M, et al. Transforming Growth Factor-Beta and Sonic Hedgehog Signaling in Palatal Epithelium Regulate Tenascin-C Expression in Palatal Mesenchyme During Soft Palate Development. Front Physiol. 2020;11:532 pubmed publisher
Io S, Kabata M, Iemura Y, Semi K, Morone N, Minagawa A, et al. Capturing human trophoblast development with naive pluripotent stem cells in vitro. Cell Stem Cell. 2021;28:1023-1039.e13 pubmed publisher
Takeo M, Asakawa K, Toyoshima K, Ogawa M, Tong J, Irie T, et al. Expansion and characterization of epithelial stem cells with potential for cyclical hair regeneration. Sci Rep. 2021;11:1173 pubmed publisher
Procopio M, László C, Al Labban D, Kim D, Bordignon P, Jo S, et al. Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation. Nat Cell Biol. 2015;17:1193-204 pubmed publisher
Harada M, Kamimura D, Arima Y, Kohsaka H, Nakatsuji Y, Nishida M, et al. Temporal expression of growth factors triggered by epiregulin regulates inflammation development. J Immunol. 2015;194:1039-46 pubmed publisher
Has C, Kiritsi D, Mellerio J, Franzke C, Wedgeworth E, Tantcheva Poor I, et al. The missense mutation p.R1303Q in type XVII collagen underlies junctional epidermolysis bullosa resembling Kindler syndrome. J Invest Dermatol. 2014;134:845-849 pubmed publisher
Grahovac J, Becker D, Wells A. Melanoma cell invasiveness is promoted at least in part by the epidermal growth factor-like repeats of tenascin-C. J Invest Dermatol. 2013;133:210-20 pubmed publisher
Kern J, Loeckermann S, Fritsch A, Hausser I, Roth W, Magin T, et al. Mechanisms of fibroblast cell therapy for dystrophic epidermolysis bullosa: high stability of collagen VII favors long-term skin integrity. Mol Ther. 2009;17:1605-15 pubmed publisher
Yates C, Whaley D, Y Chen A, Kulesekaran P, Hebda P, Wells A. ELR-negative CXC chemokine CXCL11 (IP-9/I-TAC) facilitates dermal and epidermal maturation during wound repair. Am J Pathol. 2008;173:643-52 pubmed publisher
Fritsch A, Loeckermann S, Kern J, Braun A, Bösl M, Bley T, et al. A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy. J Clin Invest. 2008;118:1669-79 pubmed publisher
Bujak M, Ren G, Kweon H, Dobaczewski M, Reddy A, Taffet G, et al. Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling. Circulation. 2007;116:2127-38 pubmed
product information
brand :
R&D Systems
master code :
MAB2138
SKU :
MAB2138-SP
product name :
Human/Mouse Tenascin C Antibody
description :
The Human/Mouse Tenascin C Antibody from R&D Systems is a rat monoclonal antibody to Tenascin C. This antibody reacts with human, mouse. The Human/Mouse Tenascin C Antibody has been validated for the following applications: Western Blot, Neutralization, Immunocytochemistry.
target :
Tenascin C
category :
Primary Antibodies
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
578
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse immature astrocyte-derived Tenascin C
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human, Mouse
specificity :
Detect human and mouse Tenascin C in Western blots.
gene symbol :
TNC
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
applications :
Western Blot, Neutralization, Immunocytochemistry
USD 2021 :
129
USD 2022 :
135 USD
alt name :
150-225, Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion, hexabrachion (tenascin C, cytotactin), hexabrachion (tenascin), HXB, HXBcytotactin, JI, MGC167029, Myotendinous antigen, neuronectin, tenascin, tenascin C, Tenascin J1, Tenascin-C, tenascin-C isoform 14/AD1/16, TNC, TN-C, TNGP
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.