product summary
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company name :
R&D Systems
product type :
antibody
product name :
TACE/ADAM17 Cytosolic Domain Antibody
catalog :
MAB21291
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
136133
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
citations: 1
Reference
Nishi E, Hiraoka Y, Yoshida K, Okawa K, Kita T. Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzyme. J Biol Chem. 2006;281:31164-72 pubmed
image
image 1 :
R&D Systems MAB21291 image 1
Detection of Human TACE/ADAM17 antibody by Western Blot.
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
MAB21291
SKU :
MAB21291
product name :
TACE/ADAM17 Cytosolic Domain Antibody
description :
The Human TACE/ADAM17 Cytosolic Domain Antibody from R&D Systems is a mouse monoclonal antibody to TACE/ADAM17. This antibody reacts with human. The Human TACE/ADAM17 Cytosolic Domain Antibody has been validated for the following applications: Immunoprecipitation,Intracellular Staining by Flow Cytometry,CyTOF-ready,Knockout Validated,Western Blot.
target :
TACE/ADAM17
unit size :
500 ug (also 25 ug)
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
136133
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human TACE/ADAM17, Asp695-Cys824, Accession # P78536
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human TACE/ADAM17 Cytosolic Domain in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human ADAM33 is observed.
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
gene symbol :
ADAM17
Antibody validation :
Knockout/Knockdown
accessionNumbers :
P78536
applications :
Immunoprecipitation,Intracellular Staining by Flow Cytometry,CyTOF-ready,Knockout Validated,Western Blot
product keywords :
MAB21291, hTACE/ADAM17 Cyto MAb 136133, Mouse Anti-Human TACE/ADAM17 Cytosolic Domain Monoclonal Antibody, Anti-TACE, Anti-ADAM17, Mouse Anti Human TACE/ADAM17 Cytosolic Domain Monoclonal Antibody, Anti-hTACE, alpha-Secretase, ADAM, Metalloprotease, Metalloproteinase, Sheddase
USD :
549
USD 2025 :
559 USD
alt names :
ADAM 17, ADAM metallopeptidase domain 17, ADAM metallopeptidase domain 18, ADAM17, ADAM18, CD156b, CD156b antigen, CSVP, disintegrin and metalloproteinase domain-containing protein 17, EC 3.4.24.86, MGC71942, Snake venom-like protease, TACEcSVP, TNF-alpha convertase, TNF-alpha converting enzyme, TNF-alpha-converting enzyme, tumor necrosis factor, alpha, converting enzyme
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.