product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TACE/ADAM17 Cytosolic Domain Antibody
catalog :
MAB2129
quantity :
500 ug (also 25 ug)
price :
549 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
136121
reactivity :
human, rat
application :
western blot, immunoprecipitation
more info or order :
citations: 2
Reference
Gooz P, Dang Y, Higashiyama S, Twal W, Haycraft C, Gooz M. A disintegrin and metalloenzyme (ADAM) 17 activation is regulated by ?5?1 integrin in kidney mesangial cells. PLoS ONE. 2012;7:e33350 pubmed publisher
Gooz P, Gooz M, Baldys A, Hoffman S. ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis. Biochem Biophys Res Commun. 2009;380:33-8 pubmed publisher
product information
master code :
MAB2129
SKU :
MAB2129
product name :
Human TACE/ADAM17 Cytosolic Domain Antibody
unit size :
500 ug (also 25 ug)
description :
The Human TACE/ADAM17 Cytosolic Domain Antibody from R&D Systems is a mouse monoclonal antibody to TACE/ADAM17. This antibody reacts with human,rat. The Human TACE/ADAM17 Cytosolic Domain Antibody has been validated for the following applications: Immunoprecipitation,Western Blot.
target :
TACE/ADAM17
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
136121
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human TACE/ADAM17, Asp695-Cys824 (predicted), Accession # P78536
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Rat
specificity :
Detects human TACE/ADAM17 Cytosolic Domain in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) ADAM8, 9, 10, 15, or 33 is observed.
gene symbol :
ADAM17
accessionNumbers :
P78536
applications :
Immunoprecipitation,Western Blot
USD :
549 USD
alt names :
ADAM 17, ADAM metallopeptidase domain 17, ADAM metallopeptidase domain 18, ADAM17, ADAM18, CD156b, CD156b antigen, CSVP, disintegrin and metalloproteinase domain-containing protein 17, EC 3.4.24.86, MGC71942, Snake venom-like protease, TACEcSVP, TNF-alpha convertase, TNF-alpha converting enzyme, TNF-alpha-converting enzyme, tumor necrosis factor, alpha, converting enzyme
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.