Mouse LYVE-1 Antibody | R&D Systems MAB2125-500 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse LYVE-1 Antibody

catalog :

MAB2125-500

quantity :

500 ug

price :

849 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

223322

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

citations: 28

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:100; loading ...; fig 1a	Frye M, Stritt S, Ortsäter H, Hernandez Vasquez M, Kaakinen M, Vicente A, et al. EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity. elife. 2020;9: pubmed publisher
	Hong S, Yang M, Cho H, Park I, Bae H, Choe K, et al. Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi. Nat Commun. 2020;11:4102 pubmed publisher
	Li L, Shirkey M, Zhang T, Xiong Y, Piao W, Saxena V, et al. The lymph node stromal laminin α5 shapes alloimmunity. J Clin Invest. 2020;130:2602-2619 pubmed publisher
	Jia X, Gábris F, Jacobsen O, Bedics G, Botz B, Helyes Z, et al. Foliate Lymphoid Aggregates as Novel Forms of Serous Lymphocyte Entry Sites of Peritoneal B Cells and High-Grade B Cell Lymphomas. J Immunol. 2020;204:23-36 pubmed publisher
	Veerman K, Tardiveau C, Martins F, Coudert J, Girard J. Single-Cell Analysis Reveals Heterogeneity of High Endothelial Venules and Different Regulation of Genes Controlling Lymphocyte Entry to Lymph Nodes. Cell Rep. 2019;26:3116-3131.e5 pubmed publisher
	Falero Perez J, Song Y, Zhao Y, Teixeira L, Sorenson C, Sheibani N. Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells. PLoS ONE. 2018;13:e0206756 pubmed publisher
	Ouarné M, Bouvard C, Boneva G, Mallet C, Ribeiro J, Desroches Castan A, et al. BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer. J Exp Clin Cancer Res. 2018;37:209 pubmed publisher
	Frye M, Taddei A, Dierkes C, Martínez Corral I, Fielden M, Ortsäter H, et al. Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program. Nat Commun. 2018;9:1511 pubmed publisher
	Beura L, Wijeyesinghe S, Thompson E, Macchietto M, Rosato P, Pierson M, et al. T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells. Immunity. 2018;48:327-338.e5 pubmed publisher
	Torcellan T, Hampton H, Bailey J, Tomura M, Brink R, Chtanova T. In vivo photolabeling of tumor-infiltrating cells reveals highly regulated egress of T-cell subsets from tumors. Proc Natl Acad Sci U S A. 2017;114:5677-5682 pubmed publisher
	Johnson L, Banerji S, Lawrance W, Gileadi U, Prota G, Holder K, et al. Dendritic cells enter lymph vessels by hyaluronan-mediated docking to the endothelial receptor LYVE-1. Nat Immunol. 2017;18:762-770 pubmed publisher
	Sun T, Yang L, Kaur H, Pestel J, Looso M, Nolte H, et al. A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib. J Cell Biol. 2017;216:199-215 pubmed publisher
	Lo T, Silveira P, Fromm P, Verma N, Vu P, Kupresanin F, et al. Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration. J Immunol. 2016;197:885-98 pubmed publisher
	Wang J, Shah D, Chen X, Anderson R, Wu M. A micro-sterile inflammation array as an adjuvant for influenza vaccines. Nat Commun. 2014;5:4447 pubmed publisher
	Wu M, Du Y, Liu Y, He Y, Yang C, Wang W, et al. Low molecular weight hyaluronan induces lymphangiogenesis through LYVE-1-mediated signaling pathways. PLoS ONE. 2014;9:e92857 pubmed publisher
	Dartsch N, Schulte D, Hägerling R, Kiefer F, Vestweber D. Fusing VE-cadherin to ?-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation. Mol Cell Biol. 2014;34:1634-48 pubmed publisher
	Thorek D, Ulmert D, Diop N, Lupu M, Doran M, Huang R, et al. Non-invasive mapping of deep-tissue lymph nodes in live animals using a multimodal PET/MRI nanoparticle. Nat Commun. 2014;5:3097 pubmed publisher
	Reichardt P, Patzak I, Jones K, Etemire E, Gunzer M, Hogg N. A role for LFA-1 in delaying T-lymphocyte egress from lymph nodes. EMBO J. 2013;32:829-43 pubmed publisher
	Zhi L, Kim P, Thompson B, Pitsillides C, Bankovich A, Yun S, et al. FTY720 blocks egress of T cells in part by abrogation of their adhesion on the lymph node sinus. J Immunol. 2011;187:2244-51 pubmed publisher
	Baluk P, Yao L, Feng J, Romano T, Jung S, Schreiter J, et al. TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice. J Clin Invest. 2009;119:2954-64 pubmed publisher
	Cho W, Albuquerque R, Kleinman M, Tarallo V, Greco A, Nozaki M, et al. Small interfering RNA-induced TLR3 activation inhibits blood and lymphatic vessel growth. Proc Natl Acad Sci U S A. 2009;106:7137-42 pubmed publisher
	Sinha R, Park C, Hwang I, Davis M, Kehrl J. B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis. Immunity. 2009;30:434-46 pubmed publisher
	Singh S, Bond V, Powell M, Singh U, Bumpers H, Grizzle W, et al. CXCR4-gp120-IIIB interactions induce caspase-mediated apoptosis of prostate cancer cells and inhibit tumor growth. Mol Cancer Ther. 2009;8:178-84 pubmed publisher
	Grigorova I, Schwab S, Phan T, Pham T, Okada T, Cyster J. Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells. Nat Immunol. 2009;10:58-65 pubmed publisher
	Pham T, Okada T, Matloubian M, Lo C, Cyster J. S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress. Immunity. 2008;28:122-33 pubmed publisher
	Kabashima K, Shiraishi N, Sugita K, Mori T, Onoue A, Kobayashi M, et al. CXCL12-CXCR4 engagement is required for migration of cutaneous dendritic cells. Am J Pathol. 2007;171:1249-57 pubmed
	Phan T, Grigorova I, Okada T, Cyster J. Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells. Nat Immunol. 2007;8:992-1000 pubmed
	Backhed F, Crawford P, O Donnell D, Gordon J. Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor. Proc Natl Acad Sci U S A. 2007;104:606-11 pubmed

product information

brand :

R&D Systems

master code :

MAB2125

SKU :

MAB2125-500

product name :

Mouse LYVE-1 Antibody

description :

The Mouse LYVE-1 Antibody from R&D Systems is a rat monoclonal antibody to LYVE-1. This antibody reacts with mouse. The Mouse LYVE-1 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Blockade of Receptor-ligand Interaction, Immunocytochemistry, CyTOF-ready.

target :

LYVE-1

category :

Primary Antibodies

unit size :

500 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

223322

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

BaF/3 mouse pro-B cell line transfected with mouse LYVE-1, Ala24-Thr234, Accession # Q8BHC0

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse LYVE-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse CD44 or recombinant human LYVE-1 is observed.

gene symbol :

LYVE1

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

Q8BHC0

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Blockade of Receptor-ligand Interaction, Immunocytochemistry, CyTOF-ready

USD 2021 :

799

USD 2022 :

849 USD

alt name :

cell surface retention sequence binding protein-1, Cell surface retention sequence-binding protein 1, CRSBP1, CRSBP-1, extracellular link domain containing 1, extracellular link domain-containing 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, lymphatic vessel endothelial hyaluronan receptor 1, lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE1, LYVE-1, UNQ230/PRO263, XLKD1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.