product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human GDNF Antibody
catalog :
MAB212-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
27106
reactivity :
human, mouse, rat
application :
western blot, ELISA, neutralization, immunohistochemistry - paraffin section
more info or order :
citations: 5
Reference
Lin C, Chang Y, Kao N, Lee W, Cross T, Lin S. 1,25(OH)2D3 Alleviates Aβ(25-35)-Induced Tau Hyperphosphorylation, Excessive Reactive Oxygen Species, and Apoptosis Through Interplay with Glial Cell Line-Derived Neurotrophic Factor Signaling in SH-SY5Y Cells. Int J Mol Sci. 2020;21: pubmed publisher
Luz M, Allen P, Bringas J, Boiko C, Stockinger D, Nikula K, et al. Intermittent convection-enhanced delivery of GDNF into rhesus monkey putamen: absence of local or cerebellar toxicity. Arch Toxicol. 2018;92:2353-2367 pubmed publisher
Moriarty N, Pandit A, Dowd E. Encapsulation of primary dopaminergic neurons in a GDNF-loaded collagen hydrogel increases their survival, re-innervation and function after intra-striatal transplantation. Sci Rep. 2017;7:16033 pubmed publisher
Airavaara M, Pickens C, Stern A, Wihbey K, Harvey B, Bossert J, et al. Endogenous GDNF in ventral tegmental area and nucleus accumbens does not play a role in the incubation of heroin craving. Addict Biol. 2011;16:261-72 pubmed publisher
Duveau V, Fritschy J. PSA-NCAM-dependent GDNF signaling limits neurodegeneration and epileptogenesis in temporal lobe epilepsy. Eur J Neurosci. 2010;32:89-98 pubmed publisher
product information
master code :
MAB212
SKU :
MAB212-100
product name :
Human GDNF Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human GDNF Antibody from R&D Systems is a mouse monoclonal antibody to GDNF. This antibody reacts with human,mouse,rat. The Human GDNF Antibody has been validated for the following applications: Neutralization,Western Blot,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair).
target :
GDNF
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
27106
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human GDNF, Arg109-Ile211, Accession # P39905
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human GDNF in ELISAs and Western blots. In sandwich ELISAs, no cross-reactivity or interference was observed with recombinant human (rh) BDNF, rhCNTF, rhNeurturin, rh▀-NGF, rhNT-3, or rhNT-4.
gene symbol :
GDNF
accessionNumbers :
P39905
applications :
Neutralization,Western Blot,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair)
USD :
469 USD
alt names :
Astrocyte-derived trophic factor, ATF, ATF1, ATF2, glial cell derived neurotrophic factor, glial cell line derived neurotrophic factor, glial cell line-derived neurotrophic factor, HFB1-GDNF, HGDNF, HSCR3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.