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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse TSG-6 Antibody
catalog :
MAB2104
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
259820
reactivity :
human, mouse
application :
western blot, ELISA, neutralization, immunohistochemistry - frozen section
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • ELISA; human; 1:1000
Zhang S, Zhu Y, Chen S, He H, Tseng S. Constitutive expression of pentraxin 3 (PTX3) protein by human amniotic membrane cells leads to formation of the heavy chain (HC)-hyaluronan (HA)-PTX3 complex. J Biol Chem. 2014;289:13531-42 pubmed publisher
  • western blot; human
Zhang S, He H, Day A, Tseng S. Constitutive expression of inter-?-inhibitor (I?I) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex. J Biol Chem. 2012;287:12433-44 pubmed publisher
  • western blot; human
He H, Li W, Tseng D, Zhang S, Chen S, Day A, et al. Biochemical characterization and function of complexes formed by hyaluronan and the heavy chains of inter-alpha-inhibitor (HC*HA) purified from extracts of human amniotic membrane. J Biol Chem. 2009;284:20136-46 pubmed publisher
Zhao S, Cui H, Fang X, Xia W, Tao C, Li J. Increased DNMT1 acetylation leads to global DNA methylation suppression in follicular granulosa cells during reproductive aging in mammals. BMC Genomics. 2024;25:1030 pubmed publisher
Anandhan S, Herbrich S, Goswami S, Guan B, Chen Y, Macaluso M, et al. TSG-6+ cancer-associated fibroblasts modulate myeloid cell responses and impair anti-tumor response to immune checkpoint therapy in pancreatic cancer. Nat Commun. 2024;15:5291 pubmed publisher
Kota D, Prabhakara K, Toledano Furman N, Bhattarai D, Chen Q, Dicarlo B, et al. Prostaglandin E2 Indicates Therapeutic Efficacy of Mesenchymal Stem Cells in Experimental Traumatic Brain Injury. Stem Cells. 2017;35:1416-1430 pubmed publisher
Mittal M, Tiruppathi C, Nepal S, Zhao Y, Grzych D, Soni D, et al. TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury. Proc Natl Acad Sci U S A. 2016;113:E8151-E8158 pubmed
Fujita R, Tamai K, Aikawa E, Nimura K, Ishino S, Kikuchi Y, et al. Endogenous mesenchymal stromal cells in bone marrow are required to preserve muscle function in mdx mice. Stem Cells. 2015;33:962-75 pubmed publisher
product information
master code :
MAB2104
SKU :
MAB2104
product name :
Human/Mouse TSG-6 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse TSG-6 Antibody from R&D Systems is a mouse monoclonal antibody to TSG-6. This antibody reacts with human,mouse. The Human/Mouse TSG-6 Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry-Frozen.
target :
TSG-6
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
259820
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human TSG-6, Trp18-Leu277, Accession # P98066
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human and mouse TSG-6 in direct ELISAs and Western blots.
gene symbol :
TNFAIP6
accessionNumbers :
P98066
applications :
Western Blot,Neutralization,Immunohistochemistry-Frozen
USD :
469 USD
alt names :
Hyaluronate-binding protein, TNF alpha-induced protein 6, TNFAIP6, TNF-stimulated gene 6 protein, TSG6, TSG-6tumor necrosis factor alpha-inducible protein 6, TSG6tumor necrosis factor-inducible gene 6 protein, Tumor necrosis factor alpha-induced protein 6, tumor necrosis factor, alpha-induced protein 6, tumor necrosis factor-stimulated gene-6 protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.