product summary
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company name :
R&D Systems
product type :
antibody
product name :
IL-8/CXCL8 Antibody
catalog :
MAB208-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
453 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6217
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, neutralization
more info or order :
citations: 109
Reference
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Zepp J, Nold Petry C, Dinarello C, Nold M. Protection from RNA and DNA viruses by IL-32. J Immunol. 2011;186:4110-8 pubmed publisher
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Osei Kumah A, Smith R, Clifton V. Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma. Cytokine. 2008;43:187-93 pubmed publisher
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Nold M, Nold Petry C, Pott G, Zepp J, Saavedra M, Kim S, et al. Endogenous IL-32 controls cytokine and HIV-1 production. J Immunol. 2008;181:557-65 pubmed
Goczalik I, Ulbricht E, Hollborn M, Raap M, Uhlmann S, Weick M, et al. Expression of CXCL8, CXCR1, and CXCR2 in neurons and glial cells of the human and rabbit retina. Invest Ophthalmol Vis Sci. 2008;49:4578-89 pubmed publisher
Qui H, Ferrell E, Nolan N, Phelps B, Tabibiazar R, Whitney D, et al. Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines. Clin Chem. 2007;53:2010-2 pubmed
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Fitzgerald D, Meade K, McEvoy A, Lillis L, Murphy E, MacHugh D, et al. Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells. Vet Immunol Immunopathol. 2007;116:59-68 pubmed
Abe Y, Fornage M, Yang C, Bui Thanh N, Wise V, Chen H, et al. L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion. Atherosclerosis. 2007;192:56-66 pubmed
Hajjar A, Harvey M, Shaffer S, Goodlett D, Sjostedt A, Edebro H, et al. Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infect Immun. 2006;74:6730-8 pubmed
Hatfield K, Ryningen A, Corbascio M, Bruserud O. Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts. Int J Cancer. 2006;119:2313-21 pubmed
Rofstad E, Mathiesen B, Kindem K, Galappathi K. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res. 2006;66:6699-707 pubmed
Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck L, et al. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin Immunol. 2006;120:220-31 pubmed
Popa E, Harmsen M, Tio R, van der Strate B, Brouwer L, Schipper M, et al. Circulating CD34+ progenitor cells modulate host angiogenesis and inflammation in vivo. J Mol Cell Cardiol. 2006;41:86-96 pubmed
Bersinger N, von Roten S, Wunder D, Raio L, Dreher E, Mueller M. PAPP-A and osteoprotegerin, together with interleukin-8 and RANTES, are elevated in the peritoneal fluid of women with endometriosis. Am J Obstet Gynecol. 2006;195:103-8 pubmed
Wunder D, Mueller M, Birkhäuser M, Bersinger N. Increased ENA-78 in the follicular fluid of patients with endometriosis. Acta Obstet Gynecol Scand. 2006;85:336-42 pubmed
Ramachandran R, Morice A, Compton S. Proteinase-activated receptor2 agonists upregulate granulocyte colony-stimulating factor, IL-8, and VCAM-1 expression in human bronchial fibroblasts. Am J Respir Cell Mol Biol. 2006;35:133-41 pubmed
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image
image 1 :
R&D Systems MAB208-100 image 1
product information
brand :
R&D Systems
master code :
MAB208
SKU :
MAB208-100
product name :
IL-8/CXCL8 Antibody
description :
The Human IL-8/CXCL8 Antibody from R&D Systems is a mouse monoclonal antibody to CXCL8/IL-8. This antibody reacts with human. The Human IL-8/CXCL8 Antibody has been validated for the following applications: Western Blot, Simple Western, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready, ELISA Capture (Matched Antibody Pair).
target :
IL-8/CXCL8
category :
Primary Antibodies
unit sizes :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
6217
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human IL-8/CXCL8, Ser28-Ser99, Accession # P10145
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human IL-8/CXCL8 in ELISAs and Western blots. In Western blots, 100% cross-reactivity with recombinant porcine IL-8/CXCL8 and no cross-reactivity with recombinant rat CXCL3/CINC-2 alpha is observed.
gene symbol :
IL8
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P10145
applications :
Western Blot, Simple Western, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready, ELISA Capture (Matched Antibody Pair)
USD :
453 USD
alt names :
3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP1, GCP-1TSG-1, IL8, interleukin 8, K60, LAI, LECT, LUCT, LYNAP, MDNCF, MDNCFb-ENAP, member 8, MONAP, MONAPGCP1, NAF, NAP1, NAP-1NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.