Human IL-7 Antibody | R&D Systems MAB207-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-7 Antibody

catalog :

MAB207-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7417

reactivity :

human

application :

western blot, ELISA, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 16

Reference
Rueschenbaum S, Cai C, Schmidt M, Schwarzkopf K, Dittmer U, Zeuzem S, et al. Translation of IRF-1 Restricts Hepatic Interleukin-7 Production to Types I and II Interferons: Implications for Hepatic Immunity. Front Immunol. 2020;11:581352 pubmed publisher
Kim S, Chang H, Volin M, Umar S, Van Raemdonck K, Chevalier A, et al. Macrophages are the primary effector cells in IL-7-induced arthritis. Cell Mol Immunol. 2019;: pubmed publisher
Murakami T, Kim J, Li Y, Green G, Shikanov A, Ono A. Secondary lymphoid organ fibroblastic reticular cells mediate trans-infection of HIV-1 via CD44-hyaluronan interactions. Nat Commun. 2018;9:2436 pubmed publisher
Zeng M, Haase A. Ex vivo Co-culture of Lymphoid Tissue Stromal Cells and T Cells. Bio Protoc. 2012;2: pubmed
Jiang J, Chen X, An H, Yang B, Zhang F, Cheng X. Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling. Sci Rep. 2016;6:32320 pubmed publisher
Bartlett A, Sanders A, Ruge F, Harding K, Jiang W. Potential implications of interleukin-7 in chronic wound healing. Exp Ther Med. 2016;12:33-40 pubmed
Nata T, Basheer A, Cocchi F, van Besien R, Massoud R, Jacobson S, et al. Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum. J Biol Chem. 2015;290:22338-51 pubmed publisher
Stone A, Vanderman K, Willey J, Long D, Register T, Shively C, et al. Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion. Osteoarthritis Cartilage. 2015;23:1780-9 pubmed publisher
Churchman S, El Jawhari J, Burska A, Parmar R, Goeb V, Conaghan P, et al. Modulation of peripheral T-cell function by interleukin-7 in rheumatoid arthritis. Arthritis Res Ther. 2014;16:511 pubmed publisher
Chen Z, Kim S, Chamberlain N, Pickens S, Volin M, Volkov S, et al. The novel role of IL-7 ligation to IL-7 receptor in myeloid cells of rheumatoid arthritis and collagen-induced arthritis. J Immunol. 2013;190:5256-66 pubmed publisher
Zeng M, Southern P, Reilly C, Beilman G, Chipman J, Schacker T, et al. Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy. PLoS Pathog. 2012;8:e1002437 pubmed publisher
Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, et al. Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma. Int J Cancer. 2009;125:1092-101 pubmed publisher
Biancotto A, Iglehart S, Lisco A, Vanpouille C, Grivel J, Lurain N, et al. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo. AIDS Res Hum Retroviruses. 2008;24:453-62 pubmed publisher
Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, et al. Ultrasensitive flow-based immunoassays using single-molecule counting. Clin Chem. 2007;53:1990-5 pubmed
Biancotto A, Grivel J, Iglehart S, Vanpouille C, Lisco A, Sieg S, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood. 2007;109:4272-9 pubmed
Storek J, Gillespy T, Lu H, Joseph A, Dawson M, Gough M, et al. Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys. Blood. 2003;101:4209-18 pubmed

product information

master code :

MAB207

SKU :

MAB207-100

product name :

Human IL-7 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human IL-7 Antibody from R&D Systems is a mouse monoclonal antibody to IL-7. This antibody reacts with human,primate - papio cynocephalus (yellow baboon). The Human IL-7 Antibody has been validated for the following applications: Neutralization,Immunohistochemistry,ELISA Development,Luminex Development,Flow Cytometry,Western Blot,ELISA Capture (Matched Antibody Pair).

target :

IL-7

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

7417

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human IL-7, Accession # P13232

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human,Primate - Papio cynocephalus (Yellow Baboon)

specificity :

Detects human IL-7 in Western blots. In ELISAs, does not cross-react with bovine FGF acidic, recombinant human (rh) G-CSF, rhGM-CSF, rhIL-1 alpha , rhIL-1▀, rhIL-2, rhIL-3, rhIL-4, rhIL-6, recombinant mouse IL-7, rhIL-8, porcine PDGF, rhTNF-alpha , rhTNF┐▀, human TGF┐▀1, or porcine TGF┐▀1.

gene symbol :

IL7

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by IL-7 and Neutralization by Human IL-7 Antibody.

accessionNumbers :

P13232

applications :

ELISA Development,Luminex Development,Flow Cytometry,Neutralization,Western Blot,ELISA Capture (Matched Antibody Pair)

USD :

499 USD

alt names :

IL7, IL-7interleukin-7, interleukin 7, Lymphopoietin-1, PBGF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage