Human IL-4 Antibody | R&D Systems MAB204 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-4 Antibody

catalog :

MAB204

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

34019

reactivity :

human

application :

western blot, neutralization

citations: 9

Reference
Hartana C, Ahlén Bergman E, Zirakzadeh A, Krantz D, Winerdal M, Winerdal M, et al. Urothelial bladder cancer may suppress perforin expression in CD8+ T cells by an ICAM-1/TGFβ2 mediated pathway. PLoS ONE. 2018;13:e0200079 pubmed publisher
Kongsbak M, von Essen M, Boding L, Levring T, Schjerling P, Lauritsen J, et al. Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. PLoS ONE. 2014;9:e96695 pubmed publisher
Chang H, Han L, Goswami R, Nguyen E, Pelloso D, Robertson M, et al. Impaired development of human Th1 cells in patients with deficient expression of STAT4. Blood. 2009;113:5887-90 pubmed publisher
Dai Z, Turtle C, Booth G, Riddell S, Gooley T, Stevens A, et al. Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus. J Exp Med. 2009;206:793-805 pubmed publisher
Acosta Rodriguez E, Napolitani G, Lanzavecchia A, Sallusto F. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol. 2007;8:942-9 pubmed
Ebert E, Mehta V. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell Immunol. 2006;241:7-13 pubmed
Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck L, et al. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin Immunol. 2006;120:220-31 pubmed
Howell M, Gallo R, Boguniewicz M, Jones J, Wong C, Streib J, et al. Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus. Immunity. 2006;24:341-8 pubmed
Wolk K, Kunz S, Asadullah K, Sabat R. Cutting edge: immune cells as sources and targets of the IL-10 family members?. J Immunol. 2002;168:5397-402 pubmed

product information

brand :

R&D Systems

master code :

MAB204

SKU :

MAB204-100

product name :

Human IL-4 Antibody

description :

The Human IL-4 Antibody from R&D Systems is a mouse monoclonal antibody to IL-4. This antibody reacts with human. The Human IL-4 Antibody has been validated for the following applications: Western Blot, Neutralization.

target :

IL-4

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

34019

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human IL-4, His25-Ser153, Accession # P05112

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IL-4 in Western blots. In Western blots, no cross-reactivity with recombinant mouse IL-4, recombinant porcine IL-4, recombinant cotton rat IL-4, recombinant rat IL-4, or recombinant human IL-13 is observed.

gene symbol :

IL4

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB204

accessionNumbers :

P05112

applications :

Western Blot, Neutralization

2020 USD :

339

2021 USD :

369 USD

alt names :

B cell growth factor 1, BCDF, B-cell stimulatory factor 1, BCGF1, BCGF-1, binetrakin, BSF1, BSF-1, IL4, IL-4B_cell stimulatory factor 1, IL4E12, interleukin 4, interleukin-4, Lymphocyte stimulatory factor 1, MGC79402, Pitrakinra

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.