Human Complement Component C5/C5a Antibody | R&D Systems MAB2037 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Complement Component C5/C5a Antibody

catalog :

MAB2037

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

295003

reactivity :

human

application :

western blot, ELISA, neutralization, blocking or activating experiments

citations: 4

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; fig s7d	Su S, Chen J, Yao H, Liu J, Yu S, Lao L, et al. CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness. Cell. 2018;172:841-856.e16 pubmed publisher
	Georgoutsou Spyridonos M, Ricklin D, Pratsinis H, Perivolioti E, Pirmettis I, Garcia B, et al. Attenuation of Staphylococcus aureus-Induced Bacteremia by Human Mini-Antibodies Targeting the Complement Inhibitory Protein Efb. J Immunol. 2015;195:3946-58 pubmed publisher
	Ramadass M, Ghebrehiwet B, Smith R, Kew R. Generation of multiple fluid-phase C3b:plasma protein complexes during complement activation: possible implications in C3 glomerulopathies. J Immunol. 2014;192:1220-30 pubmed publisher
	Kambas K, Markiewski M, Pneumatikos I, Rafail S, Theodorou V, Konstantonis D, et al. C5a and TNF-alpha up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrome. J Immunol. 2008;180:7368-75 pubmed

product information

brand :

R&D Systems

master code :

MAB2037

SKU :

MAB2037-100

product name :

Human Complement Component C5/C5a Antibody

description :

The Human Complement Component C5/C5a Antibody from R&D Systems is a mouse monoclonal antibody to Complement Component C5/C5a. This antibody reacts with human. The Human Complement Component C5/C5a Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

Complement Component C5/C5a

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

295003

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human Complement Component C5a, Thr678-Arg751, Accession # P01031

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Complement Component C5/C5a in ELISAs and Western blots. In sandwich immunoassays, detects human Complement Component C5a by itself or in the context of Complement Component C5. In Western blots, this antibody does not cross-react with recombinant human Complement Component C2, recombinant mouse (rm) Complement Component C3d, or rmComplement Component C5a.

gene symbol :

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB2037

accessionNumbers :

P01031

applications :

Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

359 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.