product summary
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company name :
R&D Systems
product type :
antibody
product name :
OV-6 Antibody
catalog :
MAB2020
quantity :
100 ug (also 25 ug)
price :
448 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OV-6
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 19
Reference
Xie Z, Li H, Hou X, Huang M, Zhu Z, Wei L, et al. Capsaicin suppresses hepatocarcinogenesis by inhibiting the stemness of hepatic progenitor cells via SIRT1/SOX2 signaling pathway. Cancer Med. 2022;11:4283-4296 pubmed publisher
Ge J, Zheng Y, Tsuchida T, Furuya K, Isoda H, Taniguchi H, et al. Hepatic stellate cells contribute to liver regeneration through galectins in hepatic stem cell niche. Stem Cell Res Ther. 2020;11:425 pubmed publisher
Zhao Y, Zhu J, Shi B, Wang X, Lu Q, Li C, et al. The transcription factor LEF1 promotes tumorigenicity and activates the TGF-β signaling pathway in esophageal squamous cell carcinoma. J Exp Clin Cancer Res. 2019;38:304 pubmed publisher
Zhao Y, Lu Q, Li C, Wang X, Jiang L, Huang L, et al. PRMT1 regulates the tumour-initiating properties of esophageal squamous cell carcinoma through histone H4 arginine methylation coupled with transcriptional activation. Cell Death Dis. 2019;10:359 pubmed publisher
Chien C, Chen Y, Chen H, Wang C, Wu S, Ho S, et al. Cells responsible for liver mass regeneration in rats with 2-acetylaminofluorene/partial hepatectomy injury. J Biomed Sci. 2018;25:39 pubmed publisher
Damiati S, Peacock M, Leonhardt S, Damiati L, Baghdadi M, Becker H, et al. Embedded Disposable Functionalized Electrochemical Biosensor with a 3D-Printed Flow Cell for Detection of Hepatic Oval Cells (HOCs). Genes (Basel). 2018;9: pubmed publisher
Wu J, Chang H, Lu M, Jou S, Chang K, Ni Y, et al. Prognostic roles of pathology markers immunoexpression and clinical parameters in Hepatoblastoma. J Biomed Sci. 2017;24:62 pubmed publisher
Wang C, Wang M, Cheng P, Huang H, Dong W, Zhang W, et al. Hepatitis B virus X protein promotes the stem-like properties of OV6+ cancer cells in hepatocellular carcinoma. Cell Death Dis. 2017;8:e2560 pubmed publisher
Deperalta D, Wei L, Ghoshal S, Schmidt B, Lauwers G, Lanuti M, et al. Metformin prevents hepatocellular carcinoma development by suppressing hepatic progenitor cell activation in a rat model of cirrhosis. Cancer. 2016;122:1216-27 pubmed publisher
Chen Y, Chen H, Chien C, Wu S, Ho Y, Yu C, et al. Contribution of Mature Hepatocytes to Biliary Regeneration in Rats with Acute and Chronic Biliary Injury. PLoS ONE. 2015;10:e0134327 pubmed publisher
Chen J, Zhang X, Xu Y, Li X, Ren S, Zhou Y, et al. Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride-Induced Cirrhosis via the Non-Canonical Wnt Pathway. PLoS ONE. 2015;10:e0130310 pubmed publisher
Ji X, Xie Y, Zhong J, Xu Q, Zeng Q, Wang Y, et al. GSK-3β suppresses the proliferation of rat hepatic oval cells through modulating Wnt/β-catenin signaling pathway. Acta Pharmacol Sin. 2015;36:334-42 pubmed publisher
Zheng Y, Tsuchida T, Shimao T, Li B, Takebe T, Zhang R, et al. The CD133+CD44+ precancerous subpopulation of oval cells is a therapeutic target for hepatocellular carcinoma. Stem Cells Dev. 2014;23:2237-49 pubmed publisher
Banga A, Greder L, Dutton J, Slack J. Stable insulin-secreting ducts formed by reprogramming of cells in the liver using a three-gene cocktail and a PPAR agonist. Gene Ther. 2014;21:19-27 pubmed publisher
Yang Z, Wang L, Hou Y, Wang X. Effects of matrine on oval cell?mediated liver regeneration and expression of RBP?J? and HES1. Mol Med Rep. 2013;7:1533-8 pubmed publisher
Wang J, Koyota S, Zhou X, Ueno Y, Ma L, Kawagoe M, et al. Expression and localization of regenerating gene I in a rat liver regeneration model. Biochem Biophys Res Commun. 2009;380:472-7 pubmed publisher
Yang W, Yan H, Chen L, Liu Q, He Y, Yu L, et al. Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells. Cancer Res. 2008;68:4287-95 pubmed publisher
Zhuang P, Zhang J, Zhu X, Zhang W, Wu W, Tan Y, et al. Two pathologic types of hepatocellular carcinoma with lymph node metastasis with distinct prognosis on the basis of CK19 expression in tumor. Cancer. 2008;112:2740-8 pubmed publisher
Dezso K, Jelnes P, László V, Baghy K, Bodor C, Paku S, et al. Thy-1 is expressed in hepatic myofibroblasts and not oval cells in stem cell-mediated liver regeneration. Am J Pathol. 2007;171:1529-37 pubmed
image
image 1 :
R&D Systems MAB2020 image 1
OV-6 antibody in BG01V Human Embryonic Stem Cells by Immunocytochemistry (ICC).
product information
brand :
R&D Systems
master code :
MAB2020
SKU :
MAB2020
product name :
OV-6 Antibody
description :
The Human/Rat OV-6 Antibody from R&D Systems is a mouse monoclonal antibody to OV-6. This antibody reacts with human, rat. The Human/Rat OV-6 Antibody has been validated for the following applications: Flow Cytometry, Immunocytochemistry, CyTOF-ready.
target :
OV-6
category :
Primary Antibodies
sizes available :
100 ug (also 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
OV-6
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Carcinogen-treated rat nodular hepatocytes
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human, Rat
specificity :
Detects human and rat OV-6 antigen
applications :
Flow Cytometry, Immunocytochemistry, CyTOF-ready
USD :
448 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.