Human IL-2 Antibody | R&D Systems MAB202 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-2 Antibody

catalog :

MAB202

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5334

reactivity :

human

application :

immunocytochemistry, neutralization, blocking or activating experiments

citations: 14

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...; fig 5g	Jiang J, Chen X, An H, Yang B, Zhang F, Cheng X. Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling. Sci Rep. 2016;6:32320 pubmed publisher
blocking or activating experiments; human; fig 3a	Nata T, Basheer A, Cocchi F, van Besien R, Massoud R, Jacobson S, et al. Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrum. J Biol Chem. 2015;290:22338-51 pubmed publisher
	Güler A, Lopez Venegas M, Adankwah E, Mayatepek E, Nausch N, Jacobsen M. Suppressor of cytokine signalling 3 is crucial for interleukin-7 receptor re-expression after T-cell activation and interleukin-7 dependent proliferation. Eur J Immunol. 2020;50:234-244 pubmed publisher
	Kim J, Jang S, Yun J, Jung M, Woo S. Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro. PLoS ONE. 2018;13:e0207090 pubmed publisher
	Carmenate T, Ortiz Y, Enamorado M, García Martínez K, Avellanet J, Moreno E, et al. Blocking IL-2 Signal In Vivo with an IL-2 Antagonist Reduces Tumor Growth through the Control of Regulatory T Cells. J Immunol. 2018;200:3475-3484 pubmed publisher
	Revu S, Wu J, Henkel M, Rittenhouse N, Menk A, Delgoffe G, et al. IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation. Cell Rep. 2018;22:2642-2653 pubmed publisher
	Locci M, Wu J, Arumemi F, Mikulski Z, Dahlberg C, Miller A, et al. Activin A programs the differentiation of human TFH cells. Nat Immunol. 2016;17:976-84 pubmed publisher
	Kim D, Zloza A, Broucek J, Schenkel J, Ruby C, Samaha G, et al. Interleukin-2 alters distribution of CD144 (VE-cadherin) in endothelial cells. J Transl Med. 2014;12:113 pubmed publisher
	Weissmüller S, Semmler L, Kalinke U, Christians S, Muller Berghaus J, Waibler Z. ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation. Blood. 2012;119:6268-77 pubmed publisher
	Hutnick N, Carnathan D, Demers K, Makedonas G, Ertl H, Betts M. Adenovirus-specific human T cells are pervasive, polyfunctional, and cross-reactive. Vaccine. 2010;28:1932-41 pubmed publisher
	Withers D, Fiorini C, Fischer R, Ettinger R, Lipsky P, Grammer A. T cell-dependent survival of CD20+ and CD20- plasma cells in human secondary lymphoid tissue. Blood. 2007;109:4856-64 pubmed
	Karenko L, Hahtola S, Päivinen S, Karhu R, Syrjä S, Kähkönen M, et al. Primary cutaneous T-cell lymphomas show a deletion or translocation affecting NAV3, the human UNC-53 homologue. Cancer Res. 2005;65:8101-10 pubmed
	Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, et al. Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells. Immunology. 2004;112:274-89 pubmed
	Herrero C, Hu X, Li W, Samuels S, Sharif M, Kotenko S, et al. Reprogramming of IL-10 activity and signaling by IFN-gamma. J Immunol. 2003;171:5034-41 pubmed

product information

brand :

R&D Systems

master code :

MAB202

SKU :

MAB202-100

product name :

Human IL-2 Antibody

description :

The Human IL-2 Antibody from R&D Systems is a mouse monoclonal antibody to IL-2. This antibody reacts with human. The Human IL-2 Antibody has been validated for the following applications: Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready.

target :

IL-2

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

5334

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human IL-2, Ala21-Thr153, Accession # NP_000577

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IL-2 in direct ELISAs. Does not cross-react with recombinant IL-2 from mouse, rat, pig, or cotton rat.

gene symbol :

IL2

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB202

accessionNumbers :

NP_000577

applications :

Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready

2020 USD :

339

2021 USD :

369 USD

alt names :

aldesleukin, IL2, IL-2lymphokine, interleukin 2, interleukin-2, involved in regulation of T-cell clonal expansion, T cell growth factor, T-cell growth factor, TCGF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.