product summary
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company name :
R&D Systems
product type :
antibody
product name :
SOX2 Antibody
catalog :
MAB2018
quantity :
100 ug (also 25 ug)
price :
453 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
245610
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 177
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; loading ...; fig e1g
da Silva F, Zhang K, Pinson A, Fatti E, Wilsch Bräuninger M, Herbst J, et al. Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex. EMBO J. 2021;40:e108041 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig 3d
Takeda H, Dondzillo A, Randall J, Gubbels S. Selective ablation of cochlear hair cells promotes engraftment of human embryonic stem cell-derived progenitors in the mouse organ of Corti. Stem Cell Res Ther. 2021;12:352 pubmed publisher
  • western blot; human; 1:200
Xiong F, Wang R, Lee J, Li S, Chen S, Liao Z, et al. RNA m6A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability. Cell Res. 2021;31:861-885 pubmed publisher
Berglar I, Hehlgans S, Wehle A, Roth C, Herold Mende C, R xf6 del F, et al. CHRDL1 Regulates Stemness in Glioma Stem-like Cells. Cells. 2022;11: pubmed publisher
Govek K, Chen S, Sgourdou P, Yao Y, Woodhouse S, Chen T, et al. Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation. Cell Rep. 2022;41:111768 pubmed publisher
Xiao Z, Shi G, Xi S, Singh A, Willette Brown J, Li X, et al. A TNFR1-UBCH10 axis drives lung squamous cell carcinoma dedifferentiation and metastasis through a cell-autonomous signaling loop. Cell Death Dis. 2022;13:885 pubmed publisher
Chimienti R, Baccega T, Torchio S, Manenti F, Pellegrini S, Cospito A, et al. Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for β cell replacement. Cell Rep. 2022;40:111423 pubmed publisher
Lauko A, Volovetz J, Turaga S, Bayık D, Silver D, Mitchell K, et al. SerpinB3 drives cancer stem cell survival in glioblastoma. Cell Rep. 2022;40:111348 pubmed publisher
Okada M, Nakagawa Saito Y, Mitobe Y, Sugai A, Togashi K, Suzuki S, et al. Inhibition of the Phospholipase Cε-c-Jun N-Terminal Kinase Axis Suppresses Glioma Stem Cell Properties. Int J Mol Sci. 2022;23: pubmed publisher
Pietrobono S, De Paolo R, Mangiameli D, Marranci A, Battisti I, Franchin C, et al. p38 MAPK-dependent phosphorylation of transcription factor SOX2 promotes an adaptive response to BRAF inhibitors in melanoma cells. J Biol Chem. 2022;298:102353 pubmed publisher
Benedetti V, Banfi F, Zaghi M, Moll Diaz R, Massimino L, Argelich L, et al. A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development. Sci Adv. 2022;8:eabn3986 pubmed publisher
Nakagawa Saito Y, Saitoh S, Mitobe Y, Sugai A, Togashi K, Suzuki S, et al. HDAC Class I Inhibitor Domatinostat Preferentially Targets Glioma Stem Cells over Their Differentiated Progeny. Int J Mol Sci. 2022;23: pubmed publisher
Lotila J, Hyv xe4 rinen T, Skottman H, Airas L, Narkilahti S, Hagman S. Establishment of a human induced pluripotent stem cell line (TAUi008-A) derived from a multiple sclerosis patient. Stem Cell Res. 2022;63:102865 pubmed publisher
Khadim R, Vadivelu R, Utami T, Torizal F, Nishikawa M, Sakai Y. Integrating Oxygen and 3D Cell Culture System: A Simple Tool to Elucidate the Cell Fate Decision of hiPSCs. Int J Mol Sci. 2022;23: pubmed publisher
Yoshida Y, Takahashi M, Yamanishi H, Nakazawa Y, Kishimoto J, Ohyama M. Changes in the Expression of Smooth Muscle Cell-Related Genes in Human Dermal Sheath Cup Cells Associated with the Treatment Outcome of Autologous Cell-Based Therapy for Male and Female Pattern Hair Loss. Int J Mol Sci. 2022;23: pubmed publisher
Han I, Bohrer L, Gibson Corley K, Wiley L, Shrestha A, Harman B, et al. Biocompatibility of Human Induced Pluripotent Stem Cell-Derived Retinal Progenitor Cell Grafts in Immunocompromised Rats. Cell Transplant. 2022;31:9636897221104451 pubmed publisher
Tisch M, Carmen De Mingo Alemany M, Suarez Cubero M, Fauth C, Defrancesco M, Zschocke J, et al. Generation of the human induced pluripotent stem cell line (IBKMOLi002-A) from PBMCs of a patient carrying the heterozygous L271H mutation of the voltage-gated calcium channel subunit Cav1.3-encoding CACNA1D gene. Stem Cell Res. 2022;61:102784 pubmed publisher
Maranga C, Pereira C, Raposo A, Vieira A, Duarte S, Bekman E, et al. Generation and characterization of induced pluripotent stem cell line (IBBISTi004-A) from an Angelman syndrome patient carrying a class II deletion of the maternal chromosome 15q11.2-q13. Stem Cell Res. 2022;61:102757 pubmed publisher
Breyer M, Klein T, Klug K, Klopocki E, Uceyler N. Generation of the induced pluripotent stem cell line UKWNLi005-A derived from a patient with the GLA mutation c.376A > G of unknown pathogenicity in Fabry disease. Stem Cell Res. 2022;61:102747 pubmed publisher
Polat B, Wohlleben G, Kosmala R, Lisowski D, Mantel F, Lewitzki V, et al. Differences in stem cell marker and osteopontin expression in primary and recurrent glioblastoma. Cancer Cell Int. 2022;22:87 pubmed publisher
Zyner K, Simeone A, Flynn S, Doyle C, Marsico G, Adhikari S, et al. G-quadruplex DNA structures in human stem cells and differentiation. Nat Commun. 2022;13:142 pubmed publisher
Notaras M, Lodhi A, Dündar F, Collier P, Sayles N, Tilgner H, et al. Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids. Mol Psychiatry. 2022;27:1416-1434 pubmed publisher
Del Giovane A, Russo M, Tirou L, Faure H, Ruat M, Balestri S, et al. Smoothened/AMP-Activated Protein Kinase Signaling in Oligodendroglial Cell Maturation. Front Cell Neurosci. 2021;15:801704 pubmed publisher
Pecori F, Kondo N, Ogura C, Miura T, Kume M, Minamijima Y, et al. Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis. Cell Rep. 2021;36:109361 pubmed publisher
Brooks B, Pradhan M, Cheng Y, Gorshkov K, Farkhondeh A, Chen C, et al. Generation of an induced pluripotent stem cell line (TRNDi031-A) from a patient with Alagille syndrome type 1 carrying a heterozygous p. C312X (c. 936 T > A) mutation in JAGGED-1. Stem Cell Res. 2021;54:102447 pubmed publisher
Ma L, Schmidt M, Morrow E. Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls. Stem Cell Res. 2021;54:102435 pubmed publisher
Notaras M, Lodhi A, Barrio Alonso E, Foord C, Rodrick T, Jones D, et al. Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids. Mol Psychiatry. 2021;: pubmed publisher
Huang X, Roeder A, Li R, Beers J, Liu C, Zou J, et al. Generation of an induced pluripotent stem cell line (TRNDi012-B) from Fibrodysplasia Ossificans Progressiva (FOP) patient carrying a heterozygous mutation c. 617G > A in the ACVR1 gene. Stem Cell Res. 2021;54:102424 pubmed publisher
Lee M, Stebbins M, Jiao H, Huang H, Leiferman E, Walczak B, et al. Comparative evaluation of isogenic mesodermal and ectomesodermal chondrocytes from human iPSCs for cartilage regeneration. Sci Adv. 2021;7: pubmed publisher
Brooks B, Yeh C, Beers J, Liu C, Cheng Y, Gorshkov K, et al. Generation of an induced pluripotent stem cell line (TRNDi030-A) from a patient with Farber disease carrying a homozygous p. Y36C (c. 107 A>G) mutation in ASAH1. Stem Cell Res. 2021;53:102387 pubmed publisher
Zhu W, Cheng Y, Xu M, Farkhondeh A, Beers J, Zou J, et al. Generation of Alagille syndrome derived induced pluripotent stem cell line carrying heterozygous mutation in the JAGGED-1 gene at splicing site (Chr20: 10,629,709C>A) before exon 11. Stem Cell Res. 2021;53:102366 pubmed publisher
Silva T, Pereira C, Raposo A, Oliveira A, Arez M, Cabral J, et al. Generation and characterization of induced pluripotent stem cells heterozygous for the Portuguese BRCA2 founder mutation. Stem Cell Res. 2021;53:102364 pubmed publisher
Lin Y, Kumar M, Ramesh N, Anderson E, Nguyen A, Kim B, et al. Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway. Nat Neurosci. 2021;24:1077-1088 pubmed publisher
Pradhan M, Farkhondeh A, Cheng Y, Xu M, Beers J, Zou J, et al. An induced pluripotent stem cell line (NCATS-CL9075) from a patient carrying compound heterozygote mutations, p.R390P and p.L318P, in the NGLY1 gene. Stem Cell Res. 2021;54:102400 pubmed publisher
Khuu M, Nallamothu T, Castro Rivera C, Arias Cavieres A, Szujewski C, Garcia Iii A. Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis. Sci Rep. 2021;11:6005 pubmed publisher
Silva T, Pereira C, Oliveira A, Raposo A, Arez M, Cabral J, et al. Generation and characterization of induced pluripotent stem cells from a family carrying the BRCA1 mutation c.3612delA. Stem Cell Res. 2021;52:102242 pubmed publisher
Bressan R, Southgate B, Ferguson K, Blin C, Grant V, Alfazema N, et al. Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants. Cell Stem Cell. 2021;28:877-893.e9 pubmed publisher
Pasquale V, Ducci G, Campioni G, Ventrici A, Assalini C, Busti S, et al. Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties. Cells. 2020;9: pubmed publisher
Ji X, Tang Q, Tang C, Wu Z, Ma L, Guo X, et al. Generation of an induced pluripotent stem cell line from an Alström Syndrome patient with ALMS1 mutation (c.3902C > A, c.6436C > T) and a gene correction isogenic iPSC line. Stem Cell Res. 2020;49:102089 pubmed publisher
Pietrobono S, Anichini G, Sala C, Manetti F, Almada L, Pepe S, et al. ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL. Nat Commun. 2020;11:5865 pubmed publisher
Xu X, Pradhan M, Xu M, Cheng Y, Beers J, Linask K, et al. Four induced pluripotent stem cell lines (TRNDi021-C, TRNDi023-D, TRNDi024-D and TRNDi025-A) generated from fibroblasts of four healthy individuals. Stem Cell Res. 2020;49:102011 pubmed publisher
Pecori F, Akimoto Y, Hanamatsu H, Furukawa J, Shinohara Y, Ikehara Y, et al. Mucin-type O-glycosylation controls pluripotency in mouse embryonic stem cells via Wnt receptor endocytosis. J Cell Sci. 2020;133: pubmed publisher
Sripathy S, Wang Y, Moses R, Fatemi A, Batista D, Maher B. Generation of 10 patient-specific induced pluripotent stem cells (iPSCs) to model Pitt-Hopkins Syndrome. Stem Cell Res. 2020;48:102001 pubmed publisher
Zalenski A, Majumder S, De K, Venere M. An interphase pool of KIF11 localizes at the basal bodies of primary cilia and a reduction in KIF11 expression alters cilia dynamics. Sci Rep. 2020;10:13946 pubmed publisher
Muzio L, Sirtori R, Gornati D, Eleuteri S, Fossaghi A, Brancaccio D, et al. Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis. Nat Commun. 2020;11:3848 pubmed publisher
Chen S, Lai W, Zhang W, Chen Q, Zhou L, So K, et al. Insulin-like growth factor 1 partially rescues early developmental defects caused by SHANK2 knockdown in human neurons. Neural Regen Res. 2020;15:2335-2343 pubmed publisher
Kaufman G, Kiburi N, Skrtic D. The self-renewal dental pulp stem cell microtissues challenged by a toxic dental monomer. Biosci Rep. 2020;40: pubmed publisher
Gomes I, de Almeida B, Dâmaso S, Mansinho A, Correia I, Henriques S, et al. Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer. Oncotarget. 2020;11:1714-1728 pubmed publisher
Mehdipour M, Skinner C, Wong N, Lieb M, Liu C, Etienne J, et al. Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin. Aging (Albany NY). 2020;12:8790-8819 pubmed publisher
Micali N, Kim S, Diaz Bustamante M, Stein O Brien G, Seo S, Shin J, et al. Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates. Cell Rep. 2020;31:107599 pubmed publisher
Kitajima R, Nakai R, Imamura T, Kameda T, Kozuka D, Hirai H, et al. Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells. Stem Cell Res. 2020;44:101749 pubmed publisher
Li R, Pradhan M, Xu M, Roeder A, Beers J, Zou J, et al. An induced pluripotent stem cell line (TRNDi001-D) from a Niemann-Pick disease type C1 (NPC1) patient carrying a homozygous p. I1061T (c. 3182T>C) mutation in the NPC1 gene. Stem Cell Res. 2020;44:101737 pubmed publisher
Su L, Lei X, Ma H, Feng C, Jiang J, Jiao J. PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain. Cell Death Differ. 2020;27:2313-2329 pubmed publisher
Hengel H, Bosso Lefèvre C, GRADY G, Szenker Ravi E, Li H, Pierce S, et al. Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy. Nat Commun. 2020;11:595 pubmed publisher
Mura M, Bastaroli F, Corli M, Ginevrino M, Calabrò F, Boni M, et al. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi006-A from a patient affected by an autosomal recessive form of long QT syndrome type 1. Stem Cell Res. 2020;42:101658 pubmed publisher
Hyvärinen T, Hyysalo A, Kapucu F, Aarnos L, Vinogradov A, Eglen S, et al. Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures. Sci Rep. 2019;9:17125 pubmed publisher
Grall E, Gourain V, Nair A, Martin E, Birling M, Freund J, et al. Severe head dysgenesis resulting from imbalance between anterior and posterior ontogenetic programs. Cell Death Dis. 2019;10:812 pubmed publisher
Stubb A, Guzman C, Närvä E, Aaron J, Chew T, Saari M, et al. Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells. Nat Commun. 2019;10:4756 pubmed publisher
Peñaranda Fajardo N, Meijer C, Liang Y, Dijkstra B, Aguirre Gamboa R, den Dunnen W, et al. ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation. Cell Death Dis. 2019;10:690 pubmed publisher
Yang S, Cheng Y, Li R, Pradhan M, Hong J, Beers J, et al. An induced pluripotent stem cell line (TRNDi010-C) from a patient carrying a homozygous p.R401X mutation in the NGLY1 gene. Stem Cell Res. 2019;39:101496 pubmed publisher
Yao J, Wu X, Zhang D, Wang L, Zhang L, Reynolds E, et al. Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations. J Clin Invest. 2019;129:3121-3133 pubmed publisher
Huang M, Tailor J, Zhen Q, Gillmor A, Miller M, Weishaupt H, et al. Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis. Cell Stem Cell. 2019;: pubmed publisher
Baskfield A, Li R, Beers J, Zou J, Liu C, Zheng W. An induced pluripotent stem cell line (TRNDi009-C) from a Niemann-Pick disease type A patient carrying a heterozygous p.L302P (c.905 T>C) mutation in the SMPD1 gene. Stem Cell Res. 2019;38:101461 pubmed publisher
Zurkirchen L, Varum S, Giger S, Klug A, Häusel J, Bossart R, et al. Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. Nat Commun. 2019;10:2192 pubmed publisher
Howden S, Hosseini Far H, Motazedian A, Elefanty A, Stanley E, Lamande S, et al. The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line. Stem Cell Res. 2019;38:101453 pubmed publisher
Hong J, Xu M, Li R, Cheng Y, Kouznetsova J, Beers J, et al. Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying a hemizygous 208insC mutation in the IDS gene. Stem Cell Res. 2019;37:101451 pubmed publisher
Calatayud C, Carola G, Fernandez Carasa I, Valtorta M, Jimenez Delgado S, Diaz M, et al. CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons. Sci Rep. 2019;9:6811 pubmed publisher
Cheng Y, Li R, Baskfield A, Beers J, Zou J, Liu C, et al. A human induced pluripotent stem cell line (TRNDi007-B) from an infantile onset Pompe patient carrying p.R854X mutation in the GAA gene. Stem Cell Res. 2019;37:101435 pubmed publisher
Regier M, Tokar J, Warrick J, Pabon L, Berthier E, Beebe D, et al. User-defined morphogen patterning for directing human cell fate stratification. Sci Rep. 2019;9:6433 pubmed publisher
Baskfield A, Li R, Beers J, Zou J, Liu C, Zheng W. Generation of an induced pluripotent stem cell line (TRNDi004-I) from a Niemann-Pick disease type B patient carrying a heterozygous mutation of p.L43_A44delLA in the SMPD1 gene. Stem Cell Res. 2019;37:101436 pubmed publisher
Mura M, Lee Y, Pisano F, Ginevrino M, Boni M, Calabrò F, et al. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi005-A from a patient carrying the KCNQ1-R190W mutation. Stem Cell Res. 2019;37:101437 pubmed publisher
Mura M, Lee Y, Pisano F, Ginevrino M, Boni M, Calabrò F, et al. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi004-A from a carrier of the KCNQ1-R594Q mutation. Stem Cell Res. 2019;37:101431 pubmed publisher
Fadhlullah S, Halim N, Yeo J, Ho R, Um P, Ang B, et al. Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness. Oncogene. 2019;: pubmed publisher
Huang W, Xu M, Li R, Baskfield A, Kouznetsova J, Beers J, et al. An induced pluripotent stem cell line (TRNDi006-A) from a MPS IIIB patient carrying homozygous mutation of p.Glu153Lys in the NAGLU gene. Stem Cell Res. 2019;37:101427 pubmed publisher
Sherman Samis M, Onallah H, Holth A, Reich R, Davidson B. SOX2 and SOX9 are markers of clinically aggressive disease in metastatic high-grade serous carcinoma. Gynecol Oncol. 2019;153:651-660 pubmed publisher
Stringer B, Day B, D Souza R, Jamieson P, Ensbey K, Bruce Z, et al. A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma. Sci Rep. 2019;9:4902 pubmed publisher
Mura M, Pisano F, Stefanello M, Ginevrino M, Boni M, Calabrò F, et al. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi007-A from a Long QT Syndrome type 1 patient carrier of two common variants in the NOS1AP gene. Stem Cell Res. 2019;36:101416 pubmed publisher
Ajmone Cat M, Onori A, Toselli C, Stronati E, Morlando M, Bozzoni I, et al. Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death. Sci Rep. 2019;9:4572 pubmed publisher
Baron D, Matheny T, Lin Y, Leszyk J, Kenna K, Gall K, et al. Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS. Hum Mol Genet. 2019;: pubmed publisher
Kim H, Park H, Choi H, Chang Y, Park H, Shin J, et al. Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids. Stem Cell Reports. 2019;: pubmed publisher
Li R, Baskfield A, Beers J, Zou J, Liu C, Alméciga Díaz C, et al. Generation of an induced pluripotent stem cell line (TRNDi005-A) from a Mucopolysaccharidosis Type IVA (MPS IVA) patient carrying compound heterozygous p.R61W and p.WT405del mutations in the GALNS gene. Stem Cell Res. 2019;36:101408 pubmed publisher
Klein T, Klug K, Henkel L, Kwok C, Edenhofer F, Klopocki E, et al. Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy. Stem Cell Res. 2019;35:101396 pubmed publisher
Melissaridou S, Wiechec E, Magan M, Jain M, Chung M, Farnebo L, et al. The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer. Cancer Cell Int. 2019;19:16 pubmed publisher
Li R, Baskfield A, Lin Y, Beers J, Zou J, Liu C, et al. Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene. Stem Cell Res. 2019;34:101374 pubmed publisher
Loo L, Simon J, Xing L, McCoy E, Niehaus J, Guo J, et al. Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019;10:134 pubmed publisher
Li R, Pradhan M, Xu M, Baskfield A, Farkhondeh A, Cheng Y, et al. Generation of an induced pluripotent stem cell line (TRNDi002-B) from a patient carrying compound heterozygous p.Q208X and p.G310G mutations in the NGLY1 gene. Stem Cell Res. 2019;34:101362 pubmed publisher
Vallejo Díez S, Fleischer A, Martín Fernández J, Sanchez Gilabert A, Bachiller D. Generation of two induced pluripotent stem cells lines from a Mucopolysaccharydosis IIIB (MPSIIIB) patient. Stem Cell Res. 2018;33:180-184 pubmed publisher
Cui C, Zhang Y, Wang C, Yuan F, Li H, Yao Y, et al. Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation. Nat Commun. 2018;9:4648 pubmed publisher
Jeong M, O Reilly M, Kirkwood N, Al Aama J, Lako M, Kros C, et al. Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells. Cell Death Dis. 2018;9:922 pubmed publisher
Klein T, Günther K, Kwok C, Edenhofer F, Uceyler N. Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene. Stem Cell Res. 2018;31:222-226 pubmed publisher
Nakai R, Ohnuki M, Kuroki K, Ito H, Hirai H, Kitajima R, et al. Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata). Sci Rep. 2018;8:12187 pubmed publisher
Vay S, Flitsch L, Rabenstein M, Rogall R, Blaschke S, Kleinhaus J, et al. The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo. J Neuroinflammation. 2018;15:226 pubmed publisher
Gao X, Yourick J, Sprando R. Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel. Stem Cell Res. 2018;31:193-196 pubmed publisher
Kwak S, Kim T, Kang B, Kim J, Lee J, Lee H, et al. Zinc finger proteins orchestrate active gene silencing during embryonic stem cell differentiation. Nucleic Acids Res. 2018;46:6592-6607 pubmed publisher
Le O, Palacio L, Bernier G, Batinic Haberle I, Hickson G, Beausejour C. INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice. Stem Cell Reports. 2018;10:1721-1733 pubmed publisher
Pastor W, Liu W, Chen D, Ho J, Kim R, Hunt T, et al. TFAP2C regulates transcription in human naive pluripotency by opening enhancers. Nat Cell Biol. 2018;20:553-564 pubmed publisher
Mura M, Ginevrino M, Zappatore R, Pisano F, Boni M, Castelletti S, et al. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi003-A from a patient affected by an autosomal recessive form of Long QT Syndrome type 1. Stem Cell Res. 2018;29:170-173 pubmed publisher
Mura M, Lee Y, Ginevrino M, Zappatore R, Pisano F, Boni M, et al. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi002-A from a patient affected by the Jervell and Lange-Nielsen syndrome and carrier of two compound heterozygous mutations on the KCNQ1 gene. Stem Cell Res. 2018;29:157-161 pubmed publisher
Lee J, Han S, Park M, Baek B, Song I, Choi M, et al. Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease. Nat Commun. 2018;9:1479 pubmed publisher
Lopez Escobar B, Caro Vega J, Vijayraghavan D, Plageman T, Sánchez Alcázar J, Moreno R, et al. The non-canonical Wnt-PCP pathway shapes the mouse caudal neural plate. Development. 2018;145: pubmed publisher
Corsini N, Peer A, Moeseneder P, Roiuk M, Burkard T, Theussl H, et al. Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. Cell Stem Cell. 2018;22:543-558.e12 pubmed publisher
Poppe D, Doerr J, Schneider M, Wilkens R, Steinbeck J, Ladewig J, et al. Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity. Stem Cells Transl Med. 2018;7:477-486 pubmed publisher
Aaberg Jessen C, Sørensen M, Matos A, Moreira J, Brunner N, Knudsen A, et al. Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas. BMC Cancer. 2018;18:270 pubmed publisher
Falnikar A, Stratton J, Lin R, Andrews C, Tyburski A, Trovillion V, et al. Differential response in novel stem cell niches of the brain following cervical spinal cord injury and traumatic brain injury. J Neurotrauma. 2018;: pubmed publisher
Chen M, Laursen S, Habekost M, Knudsen C, Buchholdt S, Huang J, et al. Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs. Front Cell Dev Biol. 2018;6:5 pubmed publisher
Vőfély G, Berecz T, Szabó E, Szebényi K, Hathy E, Orban T, et al. Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein. Mol Cell Neurosci. 2018;88:222-230 pubmed publisher
Yachie Kinoshita A, Onishi K, Ostblom J, Langley M, Pósfai E, Rossant J, et al. Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions. Mol Syst Biol. 2018;14:e7952 pubmed publisher
Naumann M, Pal A, Goswami A, Lojewski X, Japtok J, Vehlow A, et al. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation. Nat Commun. 2018;9:335 pubmed publisher
Alastrue Agudo A, Rodríguez Jiménez F, Mocholi E, De Giorgio F, Erceg S, Moreno Manzano V. FM19G11 and Ependymal Progenitor/Stem Cell Combinatory Treatment Enhances Neuronal Preservation and Oligodendrogenesis after Severe Spinal Cord Injury. Int J Mol Sci. 2018;19: pubmed publisher
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image
image 1 :
R&D Systems MAB2018 image 1
E-Cadherin and SOX2 antibody in BG01V Human Stem Cells by Immunocytochemistry (ICC).
product information
brand :
R&D Systems
master code :
MAB2018
SKU :
MAB2018
product name :
SOX2 Antibody
description :
The Human/Mouse/Rat SOX2 Antibody from R&D Systems is a mouse monoclonal antibody to SOX2. This antibody reacts with human, mouse, rat. The Human/Mouse/Rat SOX2 Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-reported.
target :
SOX2
category :
Primary Antibodies
unit sizes :
100 ug (also 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
245610
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human SOX2, Gly135-Met317, Accession # P48431
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human, Mouse, Rat
specificity :
Detects human, mouse, and rat SOX2 in Western blots.
gene symbol :
SOX2
accessionNumbers :
P48431
applications :
Western Blot, Simple Western, Immunohistochemistry, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-reported
USD :
453 USD
alt names :
ANOP3, MCOPS3, MGC2413, SRY (sex determining region Y)-box 2, SRY-related HMG-box gene 2, transcription factor SOX2, transcription factor SOX-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.