Human S1P1/EDG-1 Antibody | R&D Systems MAB2016 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human S1P1/EDG-1 Antibody

catalog :

MAB2016

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

218713

reactivity :

human

application :

flow cytometry

citations: 7

Reference
Yamamoto R, Aoki T, Koseki H, Fukuda M, Hirose J, Tsuji K, et al. A sphingosine-1-phosphate receptor type 1 agonist, ASP4058, suppresses intracranial aneurysm through promoting endothelial integrity and blocking macrophage transmigration. Br J Pharmacol. 2017;174:2085-2101 pubmed publisher
Williams P, Stilhano R, To V, Tran L, Wong K, Silva E. Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). PLoS ONE. 2015;10:e0123437 pubmed publisher
Till K, Pettitt A, Slupsky J. Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase Î´ but not SYK or BTK in chronic lymphocytic leukemia cells. J Immunol. 2015;194:2439-46 pubmed publisher
Gatfield J, Monnier L, Studer R, Bolli M, Steiner B, Nayler O. Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling. Cell Signal. 2014;26:1576-88 pubmed publisher
Cabezón R, Sintes J, Llinàs L, Benitez Ribas D. Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Immunol Lett. 2011;134:167-73 pubmed publisher
Matesanz Isabel J, Sintes J, Llinàs L, de Salort J, Lázaro A, Engel P. New B-cell CD molecules. Immunol Lett. 2011;134:104-12 pubmed publisher
Lorquet S, Berndt S, Blacher S, Gengoux E, Peulen O, Maquoi E, et al. Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment. FASEB J. 2010;24:3782-95 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB2016

SKU :

MAB2016-100

product name :

Human S1P1/EDG-1 Antibody

description :

The Human S1P1/EDG-1 Antibody from R&D Systems is a mouse monoclonal antibody to S1P1/EDG-1. This antibody reacts with human. The Human S1P1/EDG-1 Antibody has been validated for the following applications: Flow Cytometry, CyTOF-ready.

target :

S1P1/EDG-1

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

218713

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human S1P1/EDG-1, Met1-Ser382, Accession # P21453

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human S1P1/EDG-1 by flow cytometry.

gene symbol :

S1PR1

catalog number base :

MAB2016

accessionNumbers :

P21453

applications :

Flow Cytometry, CyTOF-ready

extended description :

Clone 218713 was used by HLDA to establish CD designation

2020 USD :

339

2021 USD :

359 USD

product details :

Clone 218713 was used by HLDA to establish CD designation

alt names :

CD363, CD363 antigen, CHEDG1, D1S3362, EDG1, EDG-1, EDG1edg-1, Endothelial differentiation G-protein coupled receptor 1, endothelial differentiation, sphingolipid G-protein-coupled receptor, 1, FLJ58121, S1P receptor 1, S1P receptor Edg-1, s1p1, S1P1ECGF1, S1PR1, sphingosine 1-phosphate receptor 1, sphingosine 1-phosphate receptor EDG1, Sphingosine 1-phosphate receptor Edg-1, sphingosine-1-phosphate receptor 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.