product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human KIR2DL3/CD158b2 Antibody
catalog :
MAB2014
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
180701
reactivity :
human
application :
flow cytometry
more info or order :
citations: 12
Reference
Wang J, Chai Q, Lei Z, Wang Y, He J, Ge P, et al. LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis. EMBO Mol Med. 2024;16:1755-1790 pubmed publisher
Dubreuil L, Maniangou B, Chevallier P, Quéméner A, Legrand N, Bene M, et al. Centromeric KIR AA Individuals Harbor Particular KIR Alleles Conferring Beneficial NK Cell Features with Implications in Haplo-Identical Hematopoietic Stem Cell Transplantation. Cancers (Basel). 2020;12: pubmed publisher
Gimeno L, Serrano López E, Campillo J, Cánovas Zapata M, Acuña O, Garcia Cozar F, et al. KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling. Cancers (Basel). 2020;12: pubmed publisher
Koenig A, Chen C, Marcais A, Barba T, Mathias V, Sicard A, et al. Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants. Nat Commun. 2019;10:5350 pubmed publisher
Lin Z, Kuroki K, Kuse N, Sun X, Akahoshi T, Qi Y, et al. HIV-1 Control by NK Cells via Reduced Interaction between KIR2DL2 and HLA-C?12:02/C?14:03. Cell Rep. 2016;17:2210-2220 pubmed publisher
Blom K, Braun M, Pakalnienė J, Lunemann S, Enqvist M, Dailidyte L, et al. NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection. J Immunol. 2016;197:2762-71 pubmed publisher
Horowitz A, Guethlein L, Nemat Gorgani N, Norman P, Cooley S, Miller J, et al. Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation. J Immunol. 2015;195:4524-36 pubmed publisher
Sharkey A, Xiong S, Kennedy P, Gardner L, Farrell L, Chazara O, et al. Tissue-Specific Education of Decidual NK Cells. J Immunol. 2015;195:3026-32 pubmed publisher
Enqvist M, Ask E, Forslund E, Carlsten M, Abrahamsen G, Béziat V, et al. Coordinated expression of DNAM-1 and LFA-1 in educated NK cells. J Immunol. 2015;194:4518-27 pubmed publisher
Holmes T, Wilson E, Black E, Benest A, Vaz C, Tan B, et al. Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT. Proc Natl Acad Sci U S A. 2014;111:E5688-96 pubmed publisher
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M. Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol. 2013;43:480-7 pubmed publisher
Beziat V, Descours B, Parizot C, Debre P, Vieillard V. NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs. PLoS ONE. 2010;5:e11966 pubmed publisher
product information
master code :
MAB2014
SKU :
MAB2014
product name :
Human KIR2DL3/CD158b2 Antibody
unit size :
500 ug (also 25 ug)
description :
The Human KIR2DL3/CD158b2 Antibody from R&D Systems is a mouse monoclonal antibody to KIR2DL3/CD158b2. This antibody reacts with human. The Human KIR2DL3/CD158b2 Antibody has been validated for the following applications: CyTOF-reported,CyTof,Flow Cytometry Control,Flow Cytometry.
target :
KIR2DL3/CD158b2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
180701
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
BaF3 mouse pro-B cell line transfected with human KIR2DL3/CD158b2, Accession # P43628
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human KIR2DL3/CD158b2. Stains BaF3 cells transfected with human KIR2DL3 in flow cytometry. Does not stain BaF3 cells transfected with KIR2DL1, 2DL2, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
gene symbol :
KIR2DL3
top caption :
Detection of KIR2DL3/CD158b2 antibody in Human PBMCs antibody by Flow Cytometry.
accessionNumbers :
P43628
applications :
CyTOF-reported,CyTof,Flow Cytometry Control,Flow Cytometry
USD :
559 USD
alt names :
CD158 antigen-like family member B2, CD158b2, CD158b2 antigen, CD158B2CD158b, cl-6, killer cell immunoglobulin-like receptor 2DL3, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, Killer inhibitory receptor cl 2-3, KIR-023GB, KIRCL23, KIR-K7b, KIR-K7c, MGC129943, MHC class I NK cell receptor, natural killer associated transcript 2, natural killer cell inhibitory receptor KIR2DL3, Natural killer-associated transcript 2, NKAT, nkat2, NKAT-2, nkat2a, NKAT2B, NKAT2GL183, NK-receptor, p58, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I specific NK receptor, p58.2 MHC class-I-specific NK receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.