Human CD46 Antibody | R&D Systems MAB2005 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD46 Antibody

catalog :

MAB2005

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

344519

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 3

Reference
Ellinghaus U, Cortini A, Pinder C, Le Friec G, Kemper C, Vyse T. Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosus. Eur J Immunol. 2017;47:1200-1210 pubmed publisher
Johnson J, Borisevich V, Rockx B, Parks G. A novel factor I activity in Nipah virus inhibits human complement pathways through cleavage of C3b. J Virol. 2015;89:989-98 pubmed publisher
Johnson J, Grant K, Parks G. The paramyxoviruses simian virus 5 and mumps virus recruit host cell CD46 to evade complement-mediated neutralization. J Virol. 2009;83:7602-11 pubmed publisher

product information

master code :

MAB2005

SKU :

MAB2005

product name :

Human CD46 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human CD46 Antibody from R&D Systems is a mouse monoclonal antibody to CD46. This antibody reacts with human. The Human CD46 Antibody has been validated for the following applications: ELISA Capture,Flow Cytometry,Western Blot,Functional Assay,Immunocytochemistry,CyTOF-ready.

target :

CD46

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

344519

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human CD46, Cys35-Asp328, Accession # NP_722548

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human CD46 in direct ELISAs and Western blots.

gene symbol :

CD46

accessionNumbers :

NP_722548

applications :

ELISA Capture,Flow Cytometry,Western Blot,Functional Assay,Immunocytochemistry,CyTOF-ready

USD :

489 USD

alt names :

AHUS2, CD46, CD46 antigen, CD46 molecule, complement regulatory protein, MCP, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage