product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Cerberus 1 Antibody
catalog :
MAB1986
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
225807
reactivity :
human, mouse
application :
western blot, immunohistochemistry
more info or order :
citations: 11
Reference
Schumacher S, Fernkorn M, Marten M, Chen R, Kim Y, Bedzhov I, et al. Tissue-intrinsic beta-catenin signals antagonize Nodal-driven anterior visceral endoderm differentiation. Nat Commun. 2024;15:5055 pubmed publisher
Weatherbee B, Weberling A, Gantner C, Iwamoto Stohl L, Barnikel Z, Barrie A, et al. Distinct pathways drive anterior hypoblast specification in the implanting human embryo. Nat Cell Biol. 2024;26:353-365 pubmed publisher
de Jong M, Adegeest E, B xe9 renger Currias N, Mircea M, Merks R, Semrau S. The shapes of elongating gastruloids are consistent with convergent extension driven by a combination of active cell crawling and differential adhesion. PLoS Comput Biol. 2024;20:e1011825 pubmed publisher
Ichikawa T, Zhang H, Panavaite L, Erzberger A, Fabr xe8 ges D, Snajder R, et al. An ex vivo system to study cellular dynamics underlying mouse peri-implantation development. Dev Cell. 2022;57:373-386.e9 pubmed publisher
Ivanovitch K, Soro Barrio P, Chakravarty P, Jones R, Bell D, Mousavy Gharavy S, et al. Ventricular, atrial, and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak. PLoS Biol. 2021;19:e3001200 pubmed publisher
Amadei G, Lau K, De Jonghe J, Gantner C, Sozen B, Chan C, et al. Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro. Dev Cell. 2021;56:366-382.e9 pubmed publisher
Kyprianou C, Christodoulou N, Hamilton R, Nahaboo W, Boomgaard D, Amadei G, et al. Basement membrane remodelling regulates mouse embryogenesis. Nature. 2020;582:253-258 pubmed publisher
Lee G, Fujita M, Takaoka K, Murakami Y, Fujihara Y, Kanzawa N, et al. A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO. J Cell Biol. 2016;215:705-718 pubmed
Iwashita H, Shiraki N, Sakano D, Ikegami T, Shiga M, Kume K, et al. Secreted cerberus1 as a marker for quantification of definitive endoderm differentiation of the pluripotent stem cells. PLoS ONE. 2013;8:e64291 pubmed publisher
Chi L, Saarela U, Railo A, Prunskaite Hyyryläinen R, Skovorodkin I, Anthony S, et al. A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development. PLoS ONE. 2011;6:e27676 pubmed publisher
Torres Padilla M, Richardson L, Kolasinska P, Meilhac S, Luetke Eversloh M, Zernicka Goetz M. The anterior visceral endoderm of the mouse embryo is established from both preimplantation precursor cells and by de novo gene expression after implantation. Dev Biol. 2007;309:97-112 pubmed
product information
master code :
MAB1986
SKU :
MAB1986
product name :
Mouse Cerberus 1 Antibody
unit size :
500 ug (also 25 ug)
description :
The Mouse Cerberus 1 Antibody from R&D Systems is a rat monoclonal antibody to Cerberus 1. This antibody reacts with human,mouse. The Mouse Cerberus 1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot.
target :
Cerberus 1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
225807
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Cerberus 1, Asp18-Pro272, Accession # O55233
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects mouse Cerberus 1 in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant human Cerberus, recombinant mouse (rm) DAN, or rmGremlin.
gene symbol :
CER1
accessionNumbers :
O55233
applications :
Immunohistochemistry,Western Blot
USD :
559 USD
alt names :
CER1, cerberus, cerberus 1 (Xenopus laevis) homolog (cysteine knot superfamily), cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis), cerberus-related 1, Cerberus-related protein, DAN domain family member 4, DAND4, MGC119894, MGC119895, MGC96951
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.