product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
IL-11 R alpha Antibody
catalog :
MAB1977
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
473143
reactivity :
human
application :
western blot
more info or order :
citations: 3
Reference
Schafer S, Viswanathan S, Widjaja A, Lim W, Moreno Moral A, Delaughter D, et al. IL-11 is a crucial determinant of cardiovascular fibrosis. Nature. 2017;552:110-115 pubmed publisher
Yan D, Kc R, Chen D, Xiao G, Im H. Bovine lactoferricin-induced anti-inflammation is, in part, via up-regulation of interleukin-11 by secondary activation of STAT3 in human articular cartilage. J Biol Chem. 2013;288:31655-69 pubmed publisher
Nieminen P, Morgan N, Fenwick A, Parmanen S, Veistinen L, Mikkola M, et al. Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth. Am J Hum Genet. 2011;89:67-81 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB1977
SKU :
MAB1977
product name :
IL-11 R alpha Antibody
Description :
The Human IL-11 R alpha Antibody from R&D Systems is a mouse monoclonal antibody to IL-11R alpha. This antibody reacts with human. The Human IL-11 R alpha Antibody has been validated for the following applications: Western Blot.
target :
IL-11 R alpha
category :
Primary Antibodies
unit size :
100 ug (also 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
473143
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human IL-11 R alpha , Cys26-Val363, Accession # Q14626
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human IL-11 R alpha in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with rmIL-11 R alpha or recombinant human IL-6 R alpha is observed. In Western blots, 25% cross-reactivity with recombinant mouse (rm) IL-11 R alpha is observed.
gene symbol :
IL11RA
accessionNumbers :
Q14626
applications :
Western Blot
USD :
469 USD
alt names :
AI314697, GP130, IL11R alpha, IL11RA, IL-11RA, Il11ra2, NR1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.