product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-37/IL-1F7 Antibody
catalog :
MAB1975-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
261506
reactivity :
human
application :
neutralization
more info or order :
citations: 2
Reference
Zhao Y, Ni X, Xu P, Liu Q, Sun T, Liu X, et al. Interleukin-37 reduces inflammation and impairs phagocytosis of platelets in immune thrombocytopenia (ITP). Cytokine. 2020;125:154853 pubmed publisher
Zhao M, Li Y, Guo C, Wang L, Chu H, Zhu F, et al. IL-37 isoform D downregulates pro-inflammatory cytokines expression in a Smad3-dependent manner. Cell Death Dis. 2018;9:582 pubmed publisher
product information
master code :
MAB1975
SKU :
MAB1975-100
product name :
Human IL-37/IL-1F7 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human IL-37/IL-1F7 Antibody from R&D Systems is a mouse monoclonal antibody to IL-37/IL-1F7. This antibody reacts with human,mouse. The Human IL-37/IL-1F7 Antibody has been validated for the following applications: Neutralization,Blockade of Receptor-ligand Interaction.
target :
IL-37/IL-1F7
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
261506
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human IL-37/IL-1F7, Lys27-Asp192, Accession # NP_775297
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human IL-37/IL-1F7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-1 alpha , rhIL-1▀, rhIL-1ra, rhIL-36Ra/IL-1F5, rhIL-36 alpha/IL-1F6, rhIL-36 beta/IL-1F8, or rhIL-18/IL-1F4 is observed.
gene symbol :
IL37
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human IL-37/IL-1F7 by Western Blot
accessionNumbers :
NP_775297
applications :
Neutralization,Blockade of Receptor-ligand Interaction
USD :
459 USD
alt names :
FIL1, FIL1 zeta, FIL1(ZETA), FIL1ZFIL1 zeta, IL-1F7, IL-1F7IL-1 zeta, IL1H4IL1F7 (canonical product IL-1F7b), IL-1H4IL-1F7b (IL-1H4, IL-1H, IL-1RP1), IL-1RP1IL-1X protein, IL1RP1interleukin 1 family member 7, IL-1X, IL37, interleukin 1 family, member 7 (zeta), interleukin 1, zeta, interleukin-1 family member 7, Interleukin-1 homolog 4, interleukin-1 superfamily z, Interleukin-1 zeta, Interleukin-1-related protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.