This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human CCR7 Antibody
catalog :
MAB197
quantity :
100 ug (also 25 ug)
price :
369 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
150503
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section
citations: 90
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 1d, 1g
Laufer J, Hauser M, Kindinger I, Purvanov V, Pauli A, Legler D. Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation. Cell Rep. 2019;29:995-1009.e6 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:5000; loading ...; fig 1b, 2, 5, 6
van Ipenburg J, de Waard N, Naus N, Jager M, Paridaens D, Verdijk R. Chemokine Receptor Expression Pattern Correlates to Progression of Conjunctival Melanocytic Lesions. Invest Ophthalmol Vis Sci. 2019;60:2950-2957 pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
Armas González E, Domínguez Luis M, Díaz Martín A, Arce Franco M, Castro Hernandez J, Danelon G, et al. Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis. Arthritis Res Ther. 2018;20:114 pubmed publisher
  • flow cytometry; human; loading ...; fig 2d
Molnar C, Scherer A, Baraliakos X, de Hooge M, Micheroli R, Exer P, et al. TNF blockers inhibit spinal radiographic progression in ankylosing spondylitis by reducing disease activity: results from the Swiss Clinical Quality Management cohort. Ann Rheum Dis. 2018;77:63-69 pubmed publisher
  • flow cytometry; human; 1:100; loading ...; tbl s2
Leong Y, Chen Y, Ong H, Wu D, Man K, Deléage C, et al. CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles. Nat Immunol. 2016;17:1187-96 pubmed publisher
  • flow cytometry; human; loading ...; fig 1
Chang S, Kohrt H, Maecker H. Monitoring the immune competence of cancer patients to predict outcome. Cancer Immunol Immunother. 2014;63:713-9 pubmed publisher
Haas Q, Boligan K, Jandus C, Schneider C, Simillion C, Stanczak M, et al. Siglec-9 Regulates an Effector Memory CD8+ T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer Immunol Res. 2019;7:707-718 pubmed publisher
Okoye A, Hansen S, Vaidya M, Fukazawa Y, Park H, Duell D, et al. Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound. Nat Med. 2018;24:1430-1440 pubmed publisher
Alexander T, Cheng Q, Klotsche J, Khodadadi L, Waka A, Biesen R, et al. Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors. Eur J Immunol. 2018;48:1573-1579 pubmed publisher
Rossi J, Paczkowski P, Shen Y, Morse K, Flynn B, Kaiser A, et al. Preinfusion polyfunctional anti-CD19 chimeric antigen receptor T cells associate with clinical outcomes in NHL. Blood. 2018;: pubmed publisher
Jouand N, Bressollette Bodin C, Gerard N, Giral M, Guerif P, Rodallec A, et al. HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition. PLoS Pathog. 2018;14:e1007041 pubmed publisher
Kobayashi D, Endo M, Ochi H, Hojo H, Miyasaka M, Hayasaka H. Regulation of CCR7-dependent cell migration through CCR7 homodimer formation. Sci Rep. 2017;7:8536 pubmed publisher
Mata M, Gerken C, Nguyen P, Krenciute G, Spencer D, Gottschalk S. Inducible Activation of MyD88 and CD40 in CAR T Cells Results in Controllable and Potent Antitumor Activity in Preclinical Solid Tumor Models. Cancer Discov. 2017;7:1306-1319 pubmed publisher
Van den Bergh J, Smits E, Versteven M, De Reu H, Berneman Z, Van Tendeloo V, et al. Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use. J Immunol Res. 2017;2017:1975902 pubmed publisher
Bellora F, Dondero A, Corrias M, Casu B, Regis S, Caliendo F, et al. Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages. J Immunol. 2017;199:1516-1525 pubmed publisher
Huang L, Litjens N, Kannegieter N, Klepper M, Baan C, Betjes M. pERK-dependent defective TCR-mediated activation of CD4+ T cells in end-stage renal disease patients. Immun Ageing. 2017;14:14 pubmed publisher
Nguyen S, Antony K, Dudley D, Kohn S, Simmons H, Wolfe B, et al. Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques. PLoS Pathog. 2017;13:e1006378 pubmed publisher
Zhang Z, Liu F, Li Z, Wang D, Li R, Sun C. Jak3 is involved in CCR7-dependent migration and invasion in metastatic squamous cell carcinoma of the head and neck. Oncol Lett. 2017;13:3191-3197 pubmed publisher
Karnell F, Lin D, Motley S, Duhen T, Lim N, Campbell D, et al. Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation. Clin Exp Immunol. 2017;189:268-278 pubmed publisher
Dunham J, van Driel N, Eggen B, Paul C, t Hart B, Laman J, et al. Analysis of the cross-talk of Epstein-Barr virus-infected B cells with T cells in the marmoset. Clin Transl Immunology. 2017;6:e127 pubmed publisher
Koya T, Yanagisawa R, Higuchi Y, Sano K, Shimodaira S. Interferon-α-inducible Dendritic Cells Matured with OK-432 Exhibit TRAIL and Fas Ligand Pathway-mediated Killer Activity. Sci Rep. 2017;7:42145 pubmed publisher
Pichyangkul S, Spring M, Yongvanitchit K, Kum Arb U, Limsalakpetch A, Im Erbsin R, et al. Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver. PLoS ONE. 2017;12:e0171826 pubmed publisher
Cruz A, Ramaswamy M, Ouyang C, Klebanoff C, Sengupta P, Yamamoto T, et al. Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction. Nat Commun. 2016;7:13895 pubmed publisher
Lougaris V, Patrizi O, Baronio M, Tabellini G, Tampella G, Damiati E, et al. NFKB1 regulates human NK cell maturation and effector functions. Clin Immunol. 2017;175:99-108 pubmed publisher
Sumatoh H, Teng K, Cheng Y, Newell E. Optimization of mass cytometry sample cryopreservation after staining. Cytometry A. 2017;91:48-61 pubmed publisher
Alsadeq A, Fedders H, Vokuhl C, Belau N, Zimmermann M, Wirbelauer T, et al. The role of ZAP70 kinase in acute lymphoblastic leukemia infiltration into the central nervous system. Haematologica. 2017;102:346-355 pubmed publisher
Woon H, Braun A, Li J, Smith C, Edwards J, Sierro F, et al. Compartmentalization of Total and Virus-Specific Tissue-Resident Memory CD8+ T Cells in Human Lymphoid Organs. PLoS Pathog. 2016;12:e1005799 pubmed publisher
Hsu Y, Wang M, Ho L, Lai J. Dengue virus infection induces interferon-lambda1 to facilitate cell migration. Sci Rep. 2016;6:24530 pubmed publisher
Frascoli M, Jeanty C, Fleck S, Moradi P, Keating S, Mattis A, et al. Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5. J Immunol. 2016;196:4957-66 pubmed publisher
Kelley C, Lai L, Ibegbu C, Rosenberg E, Kaur S, Patel K, et al. Differences in expression of gut-homing receptors on CD4+ T cells in black and white HIV-negative men who have sex with men. AIDS. 2016;30:1305-8 pubmed publisher
Okoye A, Rohankhedkar M, Konfe A, Abana C, Reyes M, Clock J, et al. Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques. J Immunol. 2015;195:4292-305 pubmed publisher
Pichyangkul S, Yongvanitchit K, Limsalakpetch A, Kum Arb U, Im Erbsin R, Boonnak K, et al. Tissue Distribution of Memory T and B Cells in Rhesus Monkeys following Influenza A Infection. J Immunol. 2015;195:4378-86 pubmed publisher
White M, Gomer R. Trypsin, Tryptase, and Thrombin Polarize Macrophages towards a Pro-Fibrotic M2a Phenotype. PLoS ONE. 2015;10:e0138748 pubmed publisher
Patrussi L, Capitani N, Martini V, Pizzi M, Trimarco V, Frezzato F, et al. Enhanced Chemokine Receptor Recycling and Impaired S1P1 Expression Promote Leukemic Cell Infiltration of Lymph Nodes in Chronic Lymphocytic Leukemia. Cancer Res. 2015;75:4153-63 pubmed publisher
Mei H, Leipold M, Schulz A, Chester C, Maecker H. Barcoding of live human peripheral blood mononuclear cells for multiplexed mass cytometry. J Immunol. 2015;194:2022-31 pubmed publisher
Takakura K, Koido S, Kan S, Yoshida K, Mori M, Hirano Y, et al. Prognostic markers for patient outcome following vaccination with multiple MHC Class I/II-restricted WT1 peptide-pulsed dendritic cells plus chemotherapy for pancreatic cancer. Anticancer Res. 2015;35:555-62 pubmed
Williams G, Pachnio A, Long H, Rauz S, Curnow S. Cytokine production and antigen recognition by human mucosal homing conjunctival effector memory CD8+ T cells. Invest Ophthalmol Vis Sci. 2014;55:8523-30 pubmed publisher
Xuan W, Qu Q, Zheng B, Xiong S, Fan G. The chemotaxis of M1 and M2 macrophages is regulated by different chemokines. J Leukoc Biol. 2015;97:61-9 pubmed publisher
Schanz A, Red Horse K, Hess A, Baston Büst D, Heiss C, Krüssel J. Oxygen regulates human cytotrophoblast migration by controlling chemokine and receptor expression. Placenta. 2014;35:1089-94 pubmed publisher
Lee E, Fertig E, Jin K, Sukumar S, Pandey N, Popel A. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nat Commun. 2014;5:4715 pubmed publisher
Antsiferova O, Müller A, Rämer P, Chijioke O, Chatterjee B, Raykova A, et al. Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice. PLoS Pathog. 2014;10:e1004333 pubmed publisher
Rasul E, Salamon D, Nagy N, Leveau B, Banati F, Szenthe K, et al. The MEC1 and MEC2 lines represent two CLL subclones in different stages of progression towards prolymphocytic leukemia. PLoS ONE. 2014;9:e106008 pubmed publisher
Campion S, Brodie T, Fischer W, Korber B, Rossetti A, Goonetilleke N, et al. Proteome-wide analysis of HIV-specific naive and memory CD4(+) T cells in unexposed blood donors. J Exp Med. 2014;211:1273-80 pubmed publisher
Borgman K, van Zanten T, Manzo C, Cabezón R, Cambi A, Benitez Ribas D, et al. Priming by chemokines restricts lateral mobility of the adhesion receptor LFA-1 and restores adhesion to ICAM-1 nano-aggregates on human mature dendritic cells. PLoS ONE. 2014;9:e99589 pubmed publisher
Xu Y, Zhang M, Ramos C, Durett A, Liu E, Dakhova O, et al. Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15. Blood. 2014;123:3750-9 pubmed publisher
Kap Y, van Driel N, Laman J, Tak P, t Hart B. CD20+ B cell depletion alters T cell homing. J Immunol. 2014;192:4242-53 pubmed publisher
Carrega P, Bonaccorsi I, Di Carlo E, Morandi B, Paul P, Rizzello V, et al. CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph. J Immunol. 2014;192:3805-15 pubmed publisher
Rongvaux A, Willinger T, Martinek J, Strowig T, Gearty S, Teichmann L, et al. Development and function of human innate immune cells in a humanized mouse model. Nat Biotechnol. 2014;32:364-72 pubmed publisher
Pinto S, Martinez Romero A, O Connor J, Gil Benso R, San Miguel T, Terrádez L, et al. Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation. BMC Cancer. 2014;14:118 pubmed publisher
Ishikawa T, Kokura S, Enoki T, Sakamoto N, Okayama T, Ideno M, et al. Phase I clinical trial of fibronectin CH296-stimulated T cell therapy in patients with advanced cancer. PLoS ONE. 2014;9:e83786 pubmed publisher
Somovilla Crespo B, Alfonso Pérez M, Cuesta Mateos C, Carballo de Dios C, Beltrán A, Terrón F, et al. Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma. J Hematol Oncol. 2013;6:89 pubmed publisher
Castriconi R, Dondero A, Bellora F, Moretta L, Castellano A, Locatelli F, et al. Neuroblastoma-derived TGF-β1 modulates the chemokine receptor repertoire of human resting NK cells. J Immunol. 2013;190:5321-8 pubmed publisher
Manes T, Pober J. TCR-driven transendothelial migration of human effector memory CD4 T cells involves Vav, Rac, and myosin IIA. J Immunol. 2013;190:3079-88 pubmed publisher
Mazerolles F, Picard C, Kracker S, Fischer A, Durandy A. Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency. J Allergy Clin Immunol. 2013;131:1146-56, 1156.e1-5 pubmed publisher
Santegoets S, Turksma A, Suhoski M, Stam A, Albelda S, Hooijberg E, et al. IL-21 promotes the expansion of CD27+ CD28+ tumor infiltrating lymphocytes with high cytotoxic potential and low collateral expansion of regulatory T cells. J Transl Med. 2013;11:37 pubmed publisher
Vacca P, Martini S, Garelli V, Passalacqua G, Moretta L, Mingari M. NK cells from malignant pleural effusions are not anergic but produce cytokines and display strong antitumor activity on short-term IL-2 activation. Eur J Immunol. 2013;43:550-61 pubmed publisher
Duluc D, Gannevat J, Anguiano E, Zurawski S, Carley M, Boreham M, et al. Functional diversity of human vaginal APC subsets in directing T-cell responses. Mucosal Immunol. 2013;6:626-38 pubmed publisher
Liu J, Li H, Iampietro M, Barouch D. Accelerated heterologous adenovirus prime-boost SIV vaccine in neonatal rhesus monkeys. J Virol. 2012;86:7829-35 pubmed publisher
Zielinski C, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, et al. Pathogen-induced human TH17 cells produce IFN-? or IL-10 and are regulated by IL-1?. Nature. 2012;484:514-8 pubmed publisher
Pandya A, Al Jaderi Z, Høglund R, Holmøy T, Harbo H, Norgauer J, et al. Identification of human NK17/NK1 cells. PLoS ONE. 2011;6:e26780 pubmed publisher
Meythaler M, Wang Z, Martinot A, Pryputniewicz S, Kasheta M, McClure H, et al. Early induction of polyfunctional simian immunodeficiency virus (SIV)-specific T lymphocytes and rapid disappearance of SIV from lymph nodes of sooty mangabeys during primary infection. J Immunol. 2011;186:5151-61 pubmed publisher
Islam S, Chang D, Colvin R, Byrne M, McCully M, Moser B, et al. Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells. Nat Immunol. 2011;12:167-77 pubmed publisher
Ansari A, Reimann K, Mayne A, Takahashi Y, Stephenson S, Wang R, et al. Blocking of ?4?7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques. J Immunol. 2011;186:1044-59 pubmed publisher
Antonelli L, Mahnke Y, Hodge J, Porter B, Barber D, DerSimonian R, et al. Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome. Blood. 2010;116:3818-27 pubmed publisher
Minang J, Trivett M, Bolton D, Trubey C, Estes J, Li Y, et al. Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection. J Immunol. 2010;184:315-26 pubmed publisher
Bolton D, Minang J, Trivett M, Song K, Tuscher J, Li Y, et al. Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques. J Immunol. 2010;184:303-14 pubmed publisher
Yu J, Mao H, Wei M, Hughes T, Zhang J, Park I, et al. CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets. Blood. 2010;115:274-81 pubmed publisher
Berrih Aknin S, Ruhlmann N, Bismuth J, Cizeron Clairac G, Zelman E, Shachar I, et al. CCL21 overexpressed on lymphatic vessels drives thymic hyperplasia in myasthenia. Ann Neurol. 2009;66:521-31 pubmed publisher
Birke K, Lütjen Drecoll E, Kerjaschki D, Birke M. Expression of podoplanin and other lymphatic markers in the human anterior eye segment. Invest Ophthalmol Vis Sci. 2010;51:344-54 pubmed publisher
Brusa D, Garetto S, Chiorino G, Scatolini M, Migliore E, Camussi G, et al. Post-apoptotic tumors are more palatable to dendritic cells and enhance their antigen cross-presentation activity. Vaccine. 2008;26:6422-32 pubmed publisher
Mason N, Coughlin C, Overley B, Cohen J, Mitchell E, Colligon T, et al. RNA-loaded CD40-activated B cells stimulate antigen-specific T-cell responses in dogs with spontaneous lymphoma. Gene Ther. 2008;15:955-65 pubmed publisher
Ali Z, Shao L, Halliday L, Reichenberg A, Hintz M, Jomaa H, et al. Prolonged (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate-driven antimicrobial and cytotoxic responses of pulmonary and systemic Vgamma2Vdelta2 T cells in macaques. J Immunol. 2007;179:8287-96 pubmed
Kwissa M, Amara R, Robinson H, Moss B, Alkan S, Jabbar A, et al. Adjuvanting a DNA vaccine with a TLR9 ligand plus Flt3 ligand results in enhanced cellular immunity against the simian immunodeficiency virus. J Exp Med. 2007;204:2733-46 pubmed
Yamanaka K, Dimitroff C, Fuhlbrigge R, Kakeda M, Kurokawa I, Mizutani H, et al. Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression. J Allergy Clin Immunol. 2008;121:148-157.e3 pubmed
Kang S, Lim H, Andrisani O, Broxmeyer H, Kim C. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol. 2007;179:3724-33 pubmed
Okoye A, Meier Schellersheim M, Brenchley J, Hagen S, Walker J, Rohankhedkar M, et al. Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection. J Exp Med. 2007;204:2171-85 pubmed
Shields J, Fleury M, Yong C, Tomei A, Randolph G, Swartz M. Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell. 2007;11:526-38 pubmed
Andersen H, Barsov E, Trivett M, Trubey C, Giavedoni L, Lifson J, et al. Transduction with human telomerase reverse transcriptase immortalizes a rhesus macaque CD8+ T cell clone with maintenance of surface marker phenotype and function. AIDS Res Hum Retroviruses. 2007;23:456-65 pubmed
Pierce E, Carpenter K, Jakubzick C, Kunkel S, Flaherty K, Martinez F, et al. Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice. Am J Pathol. 2007;170:1152-64 pubmed
Pierce E, Carpenter K, Jakubzick C, Kunkel S, Evanoff H, Flaherty K, et al. Idiopathic pulmonary fibrosis fibroblasts migrate and proliferate to CC chemokine ligand 21. Eur Respir J. 2007;29:1082-93 pubmed
Ni Z, Campbell J, Niehans G, Walcheck B. The monoclonal antibody CHO-131 identifies a subset of cutaneous lymphocyte-associated antigen T cells enriched in P-selectin-binding cells. J Immunol. 2006;177:4742-8 pubmed
Hirahara K, Liu L, Clark R, Yamanaka K, Fuhlbrigge R, Kupper T. The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. J Immunol. 2006;177:4488-94 pubmed
Muller A, Sonkoly E, Eulert C, Gerber P, Kubitza R, Schirlau K, et al. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int J Cancer. 2006;118:2147-57 pubmed
Mailliard R, Alber S, Shen H, Watkins S, Kirkwood J, Herberman R, et al. IL-18-induced CD83+CCR7+ NK helper cells. J Exp Med. 2005;202:941-53 pubmed
Humphreys T, Baldridge L, Billings S, Campbell J, Spinola S. Trafficking pathways and characterization of CD4 and CD8 cells recruited to the skin of humans experimentally infected with Haemophilus ducreyi. Infect Immun. 2005;73:3896-902 pubmed
Birebent B, Lorho R, Lechartier H, de Guibert S, Alizadeh M, Vu N, et al. Suppressive properties of human CD4+CD25+ regulatory T cells are dependent on CTLA-4 expression. Eur J Immunol. 2004;34:3485-96 pubmed
Ohshima K, Karube K, Kawano R, Tsuchiya T, Suefuji H, Yamaguchi T, et al. Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis. Int J Oncol. 2004;25:605-13 pubmed
Sinha R, Mage R. Developing neonatal rabbit appendix, a primary lymphoid organ, is seeded by immature blood-borne B cells: evidence for roles for CD62L/PNAd, CCR7/CCL21, alpha4beta1 and LFA-1. Dev Comp Immunol. 2004;28:829-41 pubmed
Doubrovina E, Doubrovin M, Vider E, Sisson R, O Reilly R, Dupont B, et al. Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma. J Immunol. 2003;171:6891-9 pubmed
Galli G, Nuti S, Tavarini S, Galli Stampino L, de Lalla C, Casorati G, et al. CD1d-restricted help to B cells by human invariant natural killer T lymphocytes. J Exp Med. 2003;197:1051-7 pubmed
product information
brand :
R&D Systems
master code :
MAB197
SKU :
MAB197-100
product name :
Human CCR7 Antibody
description :
The Human CCR7 Antibody from R&D Systems is a mouse monoclonal antibody to CCR7. This antibody reacts with human. The Human CCR7 Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Neutralization, Immunocytochemistry, CyTOF-reported.
target :
CCR7
category :
Primary Antibodies
unit size :
100 ug (also 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
150503
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Human CCR7 transfectants, Met1-Pro378, Accession # AAA58615
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human CCR7.
gene symbol :
CCR7
details of functionality :
ActivityAssaywCitation not found None None None None
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB197
accessionNumbers :
AAA58615
applications :
Flow Cytometry, Immunohistochemistry, Neutralization, Immunocytochemistry, CyTOF-reported
extended description :
Clone 150503 was used by HLDA to establish CD designation
2020 USD :
349
2021 USD :
369 USD
product details :
Clone 150503 was used by HLDA to establish CD designation
alt names :
BLR2, BLR2C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR7, CCR-7, CD197, CD197 antigen, CDw197, CDw197CC chemokine receptor 7, chemokine (C-C motif) receptor 7, CMKBR7, CMKBR7chemokine (C-C) receptor 7, EBI1, EBI1EBV-induced G protein-coupled receptor 1, EBV-induced G-protein coupled receptor 1, Epstein-Barr virus induced gene 1, Epstein-Barr virus induced G-protein coupled receptor, Epstein-Barr virus-induced G-protein coupled receptor 1, EVI1, lymphocyte-specific G protein-coupled peptide receptor, MIP-3 beta receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.