Mouse Fc gamma RIII (CD16) Antibody | R&D Systems MAB19601 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Fc gamma RIII (CD16) Antibody

catalog :

MAB19601

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

275003

reactivity :

human, mouse

application :

neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 14

Reference
Panda S, Wigerblad G, Jiang L, Jiménez Andrade Y, Iyer V, Shen Y, et al. IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints. Proc Natl Acad Sci U S A. 2020;117:3103-3113 pubmed publisher
Zhang P, Tu G, Wei J, Santiago P, Larrabee L, Liao Chan S, et al. Ligand-Blocking and Membrane-Proximal Domain Targeting Anti-OX40 Antibodies Mediate Potent T Cell-Stimulatory and Anti-Tumor Activity. Cell Rep. 2019;27:3117-3123.e5 pubmed publisher
Ott M, Avendaño Guzmán E, Ullrich E, Dreyer C, Strauss J, Harden M, et al. Laquinimod, a prototypic quinoline-3-carboxamide and aryl hydrocarbon receptor agonist, utilizes a CD155-mediated natural killer/dendritic cell interaction to suppress CNS autoimmunity. J Neuroinflammation. 2019;16:49 pubmed publisher
Arandjelovic S, Perry J, Lucas C, Penberthy K, Kim T, Zhou M, et al. A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis. Nat Immunol. 2019;20:141-151 pubmed publisher
Chu J, Mccormick B, Mazelyte G, Michael M, Vermeren S. HoxB8 neutrophils replicate Fcγ receptor and integrin-induced neutrophil signaling and functions. J Leukoc Biol. 2019;105:93-100 pubmed publisher
Syed S, Rau E, Ziegelmann M, Sogkas G, Brüne B, Schmidt R. C5aR activation in the absence of C5a: A new disease mechanism of autoimmune hemolytic anemia in mice. Eur J Immunol. 2018;48:696-704 pubmed publisher
Lehmann C, Baranska A, Heidkamp G, Heger L, Neubert K, Lühr J, et al. DC subset-specific induction of T cell responses upon antigen uptake via Fc? receptors in vivo. J Exp Med. 2017;214:1509-1528 pubmed publisher
Beutier H, Gillis C, Iannascoli B, Godon O, England P, Sibilano R, et al. IgG subclasses determine pathways of anaphylaxis in mice. J Allergy Clin Immunol. 2017;139:269-280.e7 pubmed publisher
Khodoun M, Kucuk Z, Strait R, Krishnamurthy D, Janek K, Clay C, et al. Rapid desensitization of mice with anti-Fc?RIIb/Fc?RIII mAb safely prevents IgG-mediated anaphylaxis. J Allergy Clin Immunol. 2013;132:1375-87 pubmed publisher
Albanesi M, Mancardi D, Macdonald L, Iannascoli B, Zitvogel L, Murphy A, et al. Cutting edge: Fc?RIII (CD16) and Fc?RI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanoma. J Immunol. 2012;189:5513-7 pubmed publisher
Kool M, Geurtsvankessel C, Muskens F, Madeira F, van Nimwegen M, Kuipers H, et al. Facilitated antigen uptake and timed exposure to TLR ligands dictate the antigen-presenting potential of plasmacytoid DCs. J Leukoc Biol. 2011;90:1177-90 pubmed publisher
Jönsson F, Mancardi D, Kita Y, Karasuyama H, Iannascoli B, Van Rooijen N, et al. Mouse and human neutrophils induce anaphylaxis. J Clin Invest. 2011;121:1484-96 pubmed publisher
Ballana E, Pauls E, Clotet B, Perron Sierra F, Tucker G, Este J. ?5 integrin is the major contributor to the ?Vintegrin-mediated blockade of HIV-1 replication. J Immunol. 2011;186:464-70 pubmed publisher
Syed S, Konrad S, Wiege K, Nieswandt B, Nimmerjahn F, Schmidt R, et al. Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a. Eur J Immunol. 2009;39:3343-56 pubmed publisher

product information

master code :

MAB19601

SKU :

MAB19601

product name :

Mouse Fc gamma RIII (CD16) Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Fc gamma RIII (CD16) Antibody from R&D Systems is a rat monoclonal antibody to Fc gamma RIII (CD16). This antibody reacts with human,mouse,transgenic mouse. The Mouse Fc gamma RIII (CD16) Antibody has been validated for the following applications: Bioassay,Flow Cytometry,Neutralization,Functional Assay,CyTOF-ready.

target :

Fc gamma RIII (CD16)

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

275003

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Fc gamma RIII, Ala31-Thr215, Accession # Q5D5J5

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Transgenic Mouse

specificity :

Detects mouse Fc gamma RIIIA/B (CD16) in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse Fcrl3/CD16-2, rmFc gamma RIA or rhFc gamma RIIA is observed.

gene symbol :

Fcgr3

top caption :

Detection of Fc gamma RIII (CD16) antibody in RAW 264.7 Mouse Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q5D5J5

applications :

Bioassay,Flow Cytometry,Neutralization,Functional Assay,CyTOF-ready

USD :

479 USD

alt names :

CD16, CD16A, Fc fragment of IgG receptor IIIa, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage