product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human Crossveinless-2/CV-2 Antibody
catalog :
MAB1956
quantity :
100 ug (also 25 ug)
price :
439 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
355304
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 5
Reference
Esser J, Steiner R, Deckler M, Schmitt H, Engert B, Link S, et al. Extracellular bone morphogenetic protein modulator BMPER and twisted gastrulation homolog 1 preserve arterial-venous specification in zebrafish blood vessel development and regulate Notch signaling in endothelial cells. FEBS J. 2018;285:1419-1436 pubmed publisher
Satomi Kobayashi S, Kinugasa M, Kobayashi R, Hatakeyama K, Kurogane Y, Ishida T, et al. Osteoblast-like differentiation of cultured human coronary artery smooth muscle cells by bone morphogenetic protein endothelial cell precursor-derived regulator (BMPER). J Biol Chem. 2012;287:30336-45 pubmed publisher
Yao Y, Jumabay M, Ly A, Radparvar M, Wang A, Abdmaulen R, et al. Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium. Blood. 2012;119:5037-47 pubmed publisher
Heinke J, Kerber M, Rahner S, Mnich L, Lassmann S, Helbing T, et al. Bone morphogenetic protein modulator BMPER is highly expressed in malignant tumors and controls invasive cell behavior. Oncogene. 2012;31:2919-30 pubmed publisher
Helbing T, Volkmar F, Goebel U, Heinke J, Diehl P, Pahl H, et al. Krüppel-like factor 15 regulates BMPER in endothelial cells. Cardiovasc Res. 2010;85:551-9 pubmed publisher
product information
master code :
MAB1956
SKU :
MAB1956
product name :
Human Crossveinless-2/CV-2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Crossveinless-2/CV-2 Antibody from R&D Systems is a rat monoclonal antibody to Crossveinless-2/CV-2/BMPER. This antibody reacts with human. The Human Crossveinless-2/CV-2 Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Immunohistochemistry,Immunocytochemistry.
target :
Crossveinless-2/CV-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
355304
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Crossveinless-2/CV-2, Val34-Arg685, Accession # Q8N8U9
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Crossveinless-2/CV-2 in direct ELISAs and Western blots. In Western blots, 25% cross-reactivity with recombinant mouse CV-2 is observed.
gene symbol :
BMPER
accessionNumbers :
Q8N8U9
applications :
Immunoprecipitation,Western Blot,Immunohistochemistry,Immunocytochemistry
USD :
439 USD
alt names :
BMP binding endothelial regulator, BMP-binding endothelial regulator precursor protein, BMP-binding endothelial regulator protein, BMPER, Bone morphogenetic protein-binding endothelial cell precursor-derived regulator, CRIM3, crossveinless 2, crossveinless-2, Cv2, CV-2, hCV2, KIAA1965, Protein crossveinless-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.