product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse Frizzled-4 Antibody
catalog :
MAB194-050
quantity :
50 ug (also 25 ug, 100 ug)
price :
249 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
145901
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 7
Reference
Ando T, Takazawa I, Spencer Z, Ito R, Tomimori Y, Mikulski Z, et al. Ileal Crohn's Disease Exhibits Reduced Activity of Phospholipase C-β3-Dependent Wnt/β-Catenin Signaling Pathway. Cells. 2024;13: pubmed publisher
Shu Z, Fan M, Tu B, Tang Z, Wang H, Li H, et al. The Lin28b/Wnt5a axis drives pancreas cancer through crosstalk between cancer associated fibroblasts and tumor epithelium. Nat Commun. 2023;14:6885 pubmed publisher
Aries A, Zanetti C, H xe9 non P, Dr xe9 nou B, Lahlil R. Deciphering the Cardiovascular Potential of Human CD34+ Stem Cells. Int J Mol Sci. 2023;24: pubmed publisher
Liu W, Zhang L, Xuan K, Hu C, Li L, Zhang Y, et al. Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia. Theranostics. 2018;8:5575-5592 pubmed publisher
Bucher F, Zhang D, Aguilar E, Sakimoto S, Diaz Aguilar S, Rosenfeld M, et al. Antibody-Mediated Inhibition of Tspan12 Ameliorates Vasoproliferative Retinopathy Through Suppression of β-Catenin Signaling. Circulation. 2017;136:180-195 pubmed publisher
Baksh D, Boland G, Tuan R. Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation. J Cell Biochem. 2007;101:1109-24 pubmed
Chen J, Park C, Tang S. Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation. J Biol Chem. 2006;281:11910-6 pubmed
product information
master code :
MAB194
SKU :
MAB194-050
product name :
Human/Mouse Frizzled-4 Antibody
unit size :
50 ug (also 25 ug, 100 ug)
description :
The Human/Mouse Frizzled-4 Antibody from R&D Systems is a rat monoclonal antibody to Frizzled-4. This antibody reacts with human,mouse,transgenic mouse. The Human/Mouse Frizzled-4 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Flow Cytometry,Immunohistochemistry-Paraffin,Immunocytochemistry,CyTOF-ready.
target :
Frizzled-4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
145901
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Frizzled-4, Phe37-Glu180, Accession # Q61088
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects human and mouse Frizzled-4 in Western blots. In Western blots, no cross-reactivity with recombinant mouse (rm) Frizzled-1, -2, -3, -6, -7, -8, or recombinant human Frizzled-5 is observed. Detects Frizzled-4 by flow cytometry and immunohistochemistry on mouse differentiated embryoid bodies derived from the mouse embryonic cell line, D3.
gene symbol :
FZD4
accessionNumbers :
Q61088
applications :
Western Blot,Flow Cytometry,Immunohistochemistry-Paraffin,Immunocytochemistry,CyTOF-ready
USD :
249 USD
alt names :
CD344, CD344 antigen, EVR1, exudative vitreoretinopathy 1, FEVR, frizzled (Drosophila) homolog 4, frizzled homolog 4 (Drosophila), frizzled-4, Frizzled4, Fz-4, FZD4, FZD4S, FzE4, GPCR, hFz4, MGC34390, WNT receptor frizzled-4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.