Human/Mouse HIF-1 alpha/HIF1A Antibody | R&D Systems MAB1935 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse HIF-1 alpha/HIF1A Antibody

catalog :

MAB1935

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

241812

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 14

Reference
Wang W, Ouyang C, Graham N, Zhang Y, Cassady K, Reyes E, et al. microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function. PLoS Biol. 2022;20:e3001552 pubmed publisher
Sun Y, Lin X, Liu B, Zhang Y, Li W, Zhang S, et al. Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells. Sci Adv. 2021;7:eabj6877 pubmed publisher
Park J, Kim H, Kim C, Kim H, Jung Y, Lee H, et al. Tumor hypoxia represses γδ T cell-mediated antitumor immunity against brain tumors. Nat Immunol. 2021;22:336-346 pubmed publisher
Nakurte I, Jekabsons K, Rembergs R, Zandberga E, Abols A, Line A, et al. Colorectal Cancer Cell Line SW480 and SW620 Released Extravascular Vesicles: Focus on Hypoxia-induced Surface Proteome Changes. Anticancer Res. 2018;38:6133-6138 pubmed publisher
Endzeliņš E, Abols A, Bušs A, Zandberga E, Palviainen M, Siljander P, et al. Extracellular Vesicles Derived from Hypoxic Colorectal Cancer Cells Confer Metastatic Phenotype to Non-metastatic Cancer Cells. Anticancer Res. 2018;38:5139-5147 pubmed publisher
Zhang J, Shan J, Chen X, Li S, Long D, Li Y. Celastrol mediates Th17 and Treg cell generation via metabolic signaling. Biochem Biophys Res Commun. 2018;497:883-889 pubmed publisher
Liu G, Bi Y, Xue L, Zhang Y, Yang H, Chen X, et al. Dendritic cell SIRT1-HIF1Î± axis programs the differentiation of CD4+ T cells through IL-12 and TGF-Î²1. Proc Natl Acad Sci U S A. 2015;112:E957-65 pubmed publisher
Mangiavini L, Merceron C, Araldi E, Khatri R, Gerard O Riley R, Wilson T, et al. Loss of VHL in mesenchymal progenitors of the limb bud alters multiple steps of endochondral bone development. Dev Biol. 2014;393:124-36 pubmed publisher
Tao L, Shi S, Chen L, Huang G. Expression of monocyte chemotactic protein-1/CCL2 in gastric cancer and its relationship with tumor hypoxia. World J Gastroenterol. 2014;20:4421-7 pubmed publisher
Chen J, Li T, Liu Q, Jiao H, Yang W, Liu X, et al. Clinical and prognostic significance of HIF-1?, PTEN, CD44v6, and survivin for gastric cancer: a meta-analysis. PLoS ONE. 2014;9:e91842 pubmed publisher
Liu L, Xie F, Chang K, Li M, Meng Y, Wang X, et al. Hypoxia promotes the proliferation of cervical carcinoma cells through stimulating the secretion of IL-8. Int J Clin Exp Pathol. 2014;7:575-83 pubmed
Lu X, Chen Y, Feng B, Mao X, Yu B, Chu X. Expression and clinical significance of CD73 and hypoxia-inducible factor-1? in gastric carcinoma. World J Gastroenterol. 2013;19:1912-8 pubmed publisher
Kueh A, Dixon M, Voss A, Thomas T. HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development. Mol Cell Biol. 2011;31:845-60 pubmed publisher
Isayeva T, Chanda D, Kallman L, Eltoum I, Ponnazhagan S. Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model. Cancer Res. 2007;67:5789-97 pubmed

product information

master code :

MAB1935

SKU :

MAB1935

product name :

Human/Mouse HIF-1 alpha/HIF1A Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse HIF-1 alpha/HIF1A Antibody from R&D Systems is a mouse monoclonal antibody to HIF-1 alpha. This antibody reacts with human,mouse. The Human/Mouse HIF-1 alpha/HIF1A Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunohistochemistry-Paraffin,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

HIF-1 alpha/HIF1A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

241812

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human HIF-1 alpha/HIF1A, Arg575-Asn826, Accession # Q16665.1

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Recognizes human and mouse HIF-1 alpha/HIF1A in direct ELISAs.

gene symbol :

HIF1A

top caption :

HIF-1 alpha/HIF1A antibody in Human Kidney Cancer Tissue by Immunohistochemistry (IHC-P).

accessionNumbers :

Q16665.1

applications :

Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready

USD :

469 USD

alt names :

AINT, anti-HIF-1 alpha, anti-HIF1A, ARNT interacting protein, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF 1A, HIF1, HIF1 alpha, HIF-1 alpha, HIF-1a, HIF1A, HIF-1alpha, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1 alpha subunit, hypoxia inducible factor 1 subunit alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1, PAS domain-containing protein 8, PASD8

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage