Human/Mouse/Rat TC-PTP Antibody | R&D Systems MAB1930 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat TC-PTP Antibody

catalog :

MAB1930

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

252294

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 7

Reference
Joshi M, Stanoev A, Huebinger J, Soetje B, Zorina V, Ro xdf mannek L, et al. The EGFR phosphatase RPTPγ is a redox-regulated suppressor of promigratory signaling. EMBO J. 2023;42:e111806 pubmed publisher
Li H, Hostager B, Arkee T, Bishop G. Multiple mechanisms for TRAF3-mediated regulation of the T cell costimulatory receptor GITR. J Biol Chem. 2021;297:101097 pubmed publisher
Lee H, Kim M, Baek M, Morales L, Jang I, Slaga T, et al. Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development. Sci Rep. 2017;7:45077 pubmed publisher
Chen X, Wang H, Liao H, Hu W, Gewin L, Mernaugh G, et al. Integrin-mediated type II TGF-? receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling. J Clin Invest. 2014;124:3295-310 pubmed publisher
Zhou W, Jeyaraman K, Yusoff P, Shenolikar S. Phosphorylation at tyrosine 262 promotes GADD34 protein turnover. J Biol Chem. 2013;288:33146-55 pubmed publisher
Moore F, Naamane N, Colli M, Bouckenooghe T, Ortis F, Gurzov E, et al. STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation. J Biol Chem. 2011;286:929-41 pubmed publisher
Borza C, Chen X, Mathew S, Mont S, Sanders C, Zent R, et al. Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase. J Biol Chem. 2010;285:40114-24 pubmed publisher

product information

master code :

MAB1930

SKU :

MAB1930

product name :

Human/Mouse/Rat TC-PTP Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat TC-PTP Antibody from R&D Systems is a mouse monoclonal antibody to TC-PTP/PTPN2. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat TC-PTP Antibody has been validated for the following applications: Immunoprecipitation,Western Blot.

target :

TC-PTP

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

252294

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human TC-PTP, Pro2-Asn314, Accession # P17706

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human, mouse, and rat TC-PTP in Western blots. In Western blots, no cross-reactivity with PTP1B is observed.

gene symbol :

PTPN2

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human/Mouse/Rat TC-PTP antibody by Western Blot.

accessionNumbers :

P17706

applications :

Immunoprecipitation,Western Blot

USD :

469 USD

alt names :

protein tyrosine phosphatase, non-receptor type 2, PTP2, PTPN2, PTPTPTN2, T-cell protein tyrosine phosphatase, T-cell protein-tyrosine phosphatase, TCELLPTP, TCPTP, TC-PTP, TCPTPEC 3.1.3.48, tyrosine-protein phosphatase non-receptor type 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage