product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human SOX17 Antibody
catalog :
MAB1924
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
245013
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 60
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:50; loading ...; fig 1d
Seol B, Kim Y, Cho Y. Modeling Sialidosis with Neural Precursor Cells Derived from Patient-Derived Induced Pluripotent Stem Cells. Int J Mol Sci. 2021;22: pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 5g
Di Luca M, Fitzpatrick E, Burtenshaw D, Liu W, Helt J, Hakimjavadi R, et al. The calcium binding protein S100β marks hedgehog-responsive resident vascular stem cells within vascular lesions. NPJ Regen Med. 2021;6:10 pubmed publisher
Hogrebe N, Schmidt M, Augsornworawat P, Gale S, Shunkarova M, Millman J. Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation. bioRxiv. 2025;: pubmed publisher
Hern xe1 ndez D, Morgan Schlicht S, Elli Clarke J, Daniszewski M, Karch C, Goate A, et al. Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation. Stem Cell Res. 2024;79:103495 pubmed publisher
Clua Provost C, Auboyer L, Rovelet Lecrux A, Monzo C, Schob E, Andreux F, et al. Generation of induced pluripotent stem cell lines IRMBi003-A and IRMBi003-B from a healthy donor to model Alzheimer's disease. Stem Cell Res. 2023;73:103250 pubmed publisher
She L, Li X, Bai M. Generation of an induced pluripotent stem cell line XJHi001-A from a fibronectin glomerulopathy patient carrying a heterozygous NM_212482.2(C.5888-1G > C) mutation in the FN1 gene. Stem Cell Res. 2023;72:103203 pubmed publisher
Provost C, Auboyer L, Rovelet Lecrux A, Monzo C, Schob E, Lehmann S, et al. Establishment of induced pluripotent stem cells IRMBi005-A from a patient with sporadic Alzheimer's disease. Stem Cell Res. 2023;72:103216 pubmed publisher
Yu L, Logsdon D, Pinzon Arteaga C, Duan J, Ezashi T, Wei Y, et al. Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk. Cell Stem Cell. 2023;30:1246-1261.e9 pubmed publisher
Jiang Z, Sun W, Zhang Q, Wang P. Generation of an induced pluripotent stem cell line (ZSZOCi001-A) from a patient with Knobloch syndrome caused by biallelic mutations in the gene COL18A1. Stem Cell Res. 2023;70:103131 pubmed publisher
Isono W, Kawasaki T, Ichida J, Nagasaka K, Hiraike O, Umezawa A, et al. Transcriptomic analysis of feeder-free culture system for maintaining naïve-state pluripotency in human pluripotent stem cells. Stem Cell Investig. 2023;10:10 pubmed publisher
Son N, Son Y, Jung C, Son M. Generation of a human fibroblast-derived induced pluripotent stem cell line KRIBBi009-A from a patient with breast cancer. Stem Cell Res. 2023;68:103060 pubmed publisher
Morita K, Nakamura A, Machida M, Kawasaki T, Nakanishi R, Ichida J, et al. Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions. Regen Ther. 2022;21:389-397 pubmed publisher
Li Y, Li Y, Liu H, Cheng L, Ma H, Xu X, et al. Generation of a human induced pluripotent stem cell line (LZUSHi002-A) from a MADD patient with ETFDH mutation. Stem Cell Res. 2022;64:102914 pubmed publisher
Chen Y, Huang P, Wen M, Pan M, Lee D, Chen T. Generation of a homozygous knock-in human embryonic stem cell line expressing mEos4b-tagged CTR1. Stem Cell Res. 2022;63:102845 pubmed publisher
Liu Y, Ling T, Wang H, Yang Y, Song W, Wang T. Generation of an integration-free induced pluripotent stem cell line (LZUSHI001-A) from an epileptic patient with DGKG mutation. Stem Cell Res. 2022;61:102768 pubmed publisher
Wang H, Luo Y, Li J, Guan J, Yang S, Wang Q. Generation of a gene corrected human isogenic iPSC line (CPGHi001-A-1) from a hearing loss patient with the TMC1 p.M418K mutation using CRISPR/Cas9. Stem Cell Res. 2022;60:102736 pubmed publisher
Xu Y, Wang X, Qiu T, Wang J, Wang Y, Wu B, et al. Generation of an induced pluripotent stem cell line (FDCHI007-A) derived from a patient with developmental and epileptic encephalopathy Type 31 carrying heterozygous c.545C > A mutation in DNM1 gene. Stem Cell Res. 2022;60:102709 pubmed publisher
Lin L, Shi K, Zhou S, Cai M, Zhang C, Sun Y, et al. SOX17 and PAX8 constitute an actionable lineage-survival transcriptional complex in ovarian cancer. Oncogene. 2022;41:1767-1779 pubmed publisher
Luo S, Xiao S, Ai Y, Wang B, Wang Y. Changes in the hepatic differentiation potential of human mesenchymal stem cells aged in vitro. Ann Transl Med. 2021;9:1628 pubmed publisher
Shin Y, Mun S, Lee J, Chung K, Kim M, Kun Cheon C, et al. Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa. Stem Cell Res. 2021;57:102584 pubmed publisher
Fan T, He J, Wang Y, Yu J, Sun W. Generation of an induced pluripotent stem cell line (FDCHi006-A) from a 7-year-old girl with central precocious puberty. Stem Cell Res. 2021;56:102542 pubmed publisher
COLLINS D, Osborn M, Steer C. Differentiation of immortalized human multi-lineage progenitor to alveolar type 2-like cells: angiotensin-converting enzyme 2 expression and binding of severe acute respiratory syndrome coronavirus 2 spike and spike 1 proteins. Cytotherapy. 2021;23:1064-1073 pubmed publisher
Hogrebe N, Maxwell K, Augsornworawat P, Millman J. Generation of insulin-producing pancreatic β cells from multiple human stem cell lines. Nat Protoc. 2021;16:4109-4143 pubmed publisher
Fischer I, Küchler J, Schaar C, Fisch T, Cernoch J, Fischer K, et al. Generation of human induced pluripotent stem cell lines from 2 patients with MIRAGE syndrome. Stem Cell Res. 2021;54:102417 pubmed publisher
Gao X, Li G, Deng H, Feng W, Li Y, Liu M, et al. Generation of an iPSC line (GWCMCi002-A) from an X-linked Alport syndrome patient with a hemizygous splicing mutation (NM_000495.4, c. 1517-1 G > T) in the COL4A5 gene. Stem Cell Res. 2021;53:102388 pubmed publisher
Li J, Wu K, Guan J, Wang Q, Wang H. Generation of a human induced pluripotent stem cell line (CPGHi003-A) from an auditory neuropathy patient with AIFM1 p.R422Q mutation. Stem Cell Res. 2021;53:102376 pubmed publisher
Jia N, Gong X, Chen J, Yang T, Bao C, Shen J, et al. Generation of an induced pluripotent stem cell line (OGHFUi001-A) from a type 1 early infantile epileptic encephalopathy with ARX mutation. Stem Cell Res. 2021;53:102367 pubmed publisher
Li N, Lin S, Li Y, Sun J, Zhang L, Chen M. An induced pluripotent stem cell line (GZHMCi004-A) derived from a fetus with heterozygous G380R mutation in FGFR3 gene causing achondroplasia. Stem Cell Res. 2021;53:102322 pubmed publisher
Gao X, Qiu S, Wang W, Kang D, Su N, Dai P, et al. Generation of a gene corrected human isogenic iPSC line (CPGHi002-A-1) from a DDOD patient with heterozygous c.1516 C>T mutation in the ATP6V1B2 gene. Stem Cell Res. 2021;53:102271 pubmed publisher
Sun X, Zhou X, Dong B, Wang C, Xiao X, Wang Y. Generation of a gene-corrected isogenic iPSC line (AHQUi001-A-1) from a patient with familial hypertriglyceridemia (FHTG) carrying a heterozygous p.C310R (c.928 T > C) mutation in LPL gene using CRISPR/Cas9. Stem Cell Res. 2021;52:102230 pubmed publisher
Chen M, Lin S, Li N, Li Y, Li Y, Zhang L. An induced pluripotent stem cell line (GZHMCi003-A) derived from a fetus with exon 3 heterozygous deletion in RUNX2 gene causing cleidocranial dysplasia. Stem Cell Res. 2021;51:102166 pubmed publisher
Koike H, Iwasawa K, Ouchi R, Maezawa M, Kimura M, Kodaka A, et al. Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells. Nat Protoc. 2021;16:919-936 pubmed publisher
Isono W, Kawasaki T, Ichida J, Ayabe T, Hiraike O, Umezawa A, et al. The combination of dibenzazepine and a DOT1L inhibitor enables a stable maintenance of human naïve-state pluripotency in non-hypoxic conditions. Regen Ther. 2020;15:161-168 pubmed publisher
Gao X, Liao X, Zhang J, Lin J, Tan M. Derivation of an induced pluripotent stem cell line (GWCMCi001-A) from PBMCs of a four-year-old male patient with Immunoglobulin A nephropathy. Stem Cell Res. 2020;50:102123 pubmed publisher
Zhu Y, Zhang S, Wu X, Lian T, He Y, Zhang Z, et al. Generation of an induced pluripotent stem cell line (PUMCHi006-A) derived from a patient with pulmonary arterial hypertension carrying heterozygous c.1339 G > A mutation in PTGIS gene. Stem Cell Res. 2020;49:102088 pubmed publisher
Ohta E, Sone T, Ukai H, Hisamatsu T, Kitagawa T, Ishikawa M, et al. Generation of gene-corrected iPSCs line (KEIUi001-A) from a PARK8 patient iPSCs with familial Parkinson's disease carrying the I2020T mutation in LRRK2. Stem Cell Res. 2020;49:102073 pubmed publisher
Gao X, Qiu S, Feng M, Huang S, Kang D, Han M, et al. Establishment of human induced pluripotent stem cell line (CPGHi002-A) from a 10-month-old female patient with DDOD syndrome carrying a heterozygous c.1516 C > T mutation in ATP6V1B2. Stem Cell Res. 2020;48:101986 pubmed publisher
Zheng Z, Lu W, Pei Z, Chen J, Yang T, Luo F. Generation of an induced pluripotent stem cell line (CHFUi001-A) from an osteogenesis imperfecta patient with COL1A2 mutation. Stem Cell Res. 2020;47:101907 pubmed publisher
Aravalli R, COLLINS D, Hapke J, Crane A, Steer C. Hepatic Differentiation of Marmoset Embryonic Stem Cells and Functional Characterization of ESC-Derived Hepatocyte-Like Cells. Hepat Med. 2020;12:15-27 pubmed publisher
Zhou H, Zhou X, Lu J, Jia W, Kang J. An induced pluripotent stem cell line (SHEHi002-A (5426))from a patient of long QT syndrome type 8 with c.2573G>A mutation in the gene CACNA1C. Stem Cell Res. 2020;43:101731 pubmed publisher
Wang Q, Vossen A, Ikeda Y, Devaux P. Measles vector as a multigene delivery platform facilitating iPSC reprogramming. Gene Ther. 2019;26:151-164 pubmed publisher
Jeon H, Kim J, Choi J, Han E, Song C, Lee J, et al. Effects of the Extracts from Fruit and Stem of Camellia japonica on Induced Pluripotency and Wound Healing. J Clin Med. 2018;7: pubmed publisher
Tandon R, Brändl B, Baryshnikova N, Landshammer A, Steenpaß L, Keminer O, et al. Generation of two human isogenic iPSC lines from fetal dermal fibroblasts. Stem Cell Res. 2018;33:120-124 pubmed publisher
Yu L, Li J, Hong J, Takashima Y, Fujimoto N, Nakajima M, et al. Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells. Stem Cell Reports. 2018;11:142-156 pubmed publisher
Hayer S, Schelling Y, Hoeflinger P, Hauser S, Schols L. Generation of an induced pluripotent stem cell line from a patient with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP): HIHCNi003-A. Stem Cell Res. 2018;30:206-209 pubmed publisher
Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed publisher
Son M, Lee M, Jeon H, Seol B, Kim J, Chang J, et al. Generation and characterization of integration-free induced pluripotent stem cells from patients with autoimmune disease. Exp Mol Med. 2016;48:e232 pubmed publisher
Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, et al. PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation. Nat Commun. 2015;6:7212 pubmed publisher
Lankford L, Selby T, Becker J, Ryzhuk V, Long C, Farmer D, et al. Early gestation chorionic villi-derived stromal cells for fetal tissue engineering. World J Stem Cells. 2015;7:195-207 pubmed publisher
Tian L, Prasad N, Jang Y. In Vitro Modeling of Alcohol-Induced Liver Injury Using Human-Induced Pluripotent Stem Cells. Methods Mol Biol. 2016;1353:271-83 pubmed publisher
Thatava T, Kudva Y, Edukulla R, Squillace K, De Lamo J, Khan Y, et al. Intrapatient variations in type 1 diabetes-specific iPS cell differentiation into insulin-producing cells. Mol Ther. 2013;21:228-39 pubmed publisher
Sui L, Mfopou J, Geens M, Sermon K, Bouwens L. FGF signaling via MAPK is required early and improves Activin A-induced definitive endoderm formation from human embryonic stem cells. Biochem Biophys Res Commun. 2012;426:380-5 pubmed publisher
Sui L, Mfopou J, Chen B, Sermon K, Bouwens L. Transplantation of human embryonic stem cell-derived pancreatic endoderm reveals a site-specific survival, growth, and differentiation. Cell Transplant. 2013;22:821-30 pubmed
Ohmine S, Squillace K, Hartjes K, Deeds M, Armstrong A, Thatava T, et al. Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency. Aging (Albany NY). 2012;4:60-73 pubmed
Ohmine S, Dietz A, Deeds M, Hartjes K, Miller D, Thatava T, et al. Induced pluripotent stem cells from GMP-grade hematopoietic progenitor cells and mononuclear myeloid cells. Stem Cell Res Ther. 2011;2:46 pubmed publisher
Thatava T, Nelson T, Edukulla R, Sakuma T, Ohmine S, Tonne J, et al. Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny. Gene Ther. 2011;18:283-93 pubmed publisher
Stefanovic S, Abboud N, Désilets S, Nury D, Cowan C, Puceat M. Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate. J Cell Biol. 2009;186:665-73 pubmed publisher
Tesar P, Chenoweth J, Brook F, Davies T, Evans E, Mack D, et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature. 2007;448:196-9 pubmed
Vallier L, Alexander M, Pedersen R. Conditional gene expression in human embryonic stem cells. Stem Cells. 2007;25:1490-7 pubmed
Kim B, Kim S, Shim J, Woo D, Gil J, Kim S, et al. Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells. FEBS Lett. 2006;580:5869-74 pubmed
product information
master code :
MAB1924
SKU :
MAB1924
product name :
Human SOX17 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human SOX17 Antibody from R&D Systems is a mouse monoclonal antibody to SOX17. This antibody reacts with human,mouse. The Human SOX17 Antibody has been validated for the following applications: Immunocytochemistry,Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence.
target :
SOX17
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
245013
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human SOX17, Asp177-Val414, Accession # Q9H6I2
isotype :
IgG3
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human SOX17 in direct ELISAs. In direct ELISAs, this antibody does not cross-react with recombinant human SOX2, 3, 7, or 10.
gene symbol :
SOX17
top caption :
SOX17 antibody in B16 Mouse Cell Line by Immunocytochemistry (ICC).
accessionNumbers :
Q9H6I2
applications :
Immunocytochemistry,Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence
USD :
479 USD
alt names :
FLJ22252, SRY (sex determining region Y)-box 17, SRY-related HMG-box transcription factor SOX17, transcription factor SOX-17, VUR3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.