Human CXCR5 Antibody | R&D Systems MAB190 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCR5 Antibody

catalog :

MAB190

quantity :

100 ug (also 25 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

51505

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 29

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human; loading ...; fig 2e	Julia A, Avila G, Celis R, Sanmarti R, Ramirez J, Marsal S, et al. Lower peripheral helper T cell levels in the synovium are associated with a better response to anti-TNF therapy in rheumatoid arthritis. Arthritis Res Ther. 2020;22:196 pubmed publisher
flow cytometry; human; loading ...; fig 1a	Armas González E, Domínguez Luis M, Díaz Martín A, Arce Franco M, Castro Hernandez J, Danelon G, et al. Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis. Arthritis Res Ther. 2018;20:114 pubmed publisher
immunohistochemistry - paraffin section; human; loading ...; fig 1d	Papa I, Saliba D, Ponzoni M, Bustamante S, Canete P, Gonzalez Figueroa P, et al. TFH-derived dopamine accelerates productive synapses in germinal centres. Nature. 2017;547:318-323 pubmed publisher
immunohistochemistry - frozen section; human; 1:300; loading ...	Rao D, Gurish M, Marshall J, Slowikowski K, Fonseka C, Liu Y, et al. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017;542:110-114 pubmed publisher
flow cytometry; human; loading ...; tbl 3	Dyer W, Tan J, Day T, Kiers L, Kiernan M, Yiannikas C, et al. Immunomodulation of inflammatory leukocyte markers during intravenous immunoglobulin treatment associated with clinical efficacy in chronic inflammatory demyelinating polyradiculoneuropathy. Brain Behav. 2016;6:e00516 pubmed
flow cytometry; human; loading ...; fig 2b	Li H, Borrego F, Nagata S, Tolnay M. Fc Receptor-like 5 Expression Distinguishes Two Distinct Subsets of Human Circulating Tissue-like Memory B Cells. J Immunol. 2016;196:4064-74 pubmed publisher
	Aqrawi L, Ivanchenko M, Bjork A, Ramírez Sepúlveda J, Imgenberg Kreuz J, Kvarnstrom M, et al. Diminished CXCR5 expression in peripheral blood of patients with Sjögren's syndrome may relate to both genotype and salivary gland homing. Clin Exp Immunol. 2018;192:259-270 pubmed publisher
	Mitkin N, Hook C, Schwartz A, Biswas S, Kochetkov D, Muratova A, et al. p53-dependent expression of CXCR5 chemokine receptor in MCF-7 breast cancer cells. Sci Rep. 2015;5:9330 pubmed publisher
	Chu R, Reczek D, Brondyk W. Capture-stabilize approach for membrane protein SPR assays. Sci Rep. 2014;4:7360 pubmed publisher
	Rasul E, Salamon D, Nagy N, Leveau B, Banati F, Szenthe K, et al. The MEC1 and MEC2 lines represent two CLL subclones in different stages of progression towards prolymphocytic leukemia. PLoS ONE. 2014;9:e106008 pubmed publisher
	Humpert M, Pinto D, Jarrossay D, Thelen M. CXCR7 influences the migration of B cells during maturation. Eur J Immunol. 2014;44:694-705 pubmed publisher
	Mazerolles F, Picard C, Kracker S, Fischer A, Durandy A. Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency. J Allergy Clin Immunol. 2013;131:1146-56, 1156.e1-5 pubmed publisher
	Sarra M, Cupi M, Monteleone I, Franzè E, Ronchetti G, Di Sabatino A, et al. IL-15 positively regulates IL-21 production in celiac disease mucosa. Mucosal Immunol. 2013;6:244-55 pubmed publisher
	Islam S, Chang D, Colvin R, Byrne M, McCully M, Moser B, et al. Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells. Nat Immunol. 2011;12:167-77 pubmed publisher
	Weiss N, Deboux C, Chaverot N, Miller F, Baron van Evercooren A, Couraud P, et al. IL8 and CXCL13 are potent chemokines for the recruitment of human neural precursor cells across brain endothelial cells. J Neuroimmunol. 2010;223:131-4 pubmed publisher
	Singh S, Singh R, Sharma P, Singh U, Rai S, Chung L, et al. Serum CXCL13 positively correlates with prostatic disease, prostate-specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion. Cancer Lett. 2009;283:29-35 pubmed publisher
	Panse J, Friedrichs K, Marx A, Hildebrandt Y, Luetkens T, Barrels K, et al. Chemokine CXCL13 is overexpressed in the tumour tissue and in the peripheral blood of breast cancer patients. Br J Cancer. 2008;99:930-8 pubmed publisher
	Cagigi A, Mowafi F, Phuong Dang L, Tenner Racz K, Atlas A, Grutzmeier S, et al. Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection. Blood. 2008;112:4401-10 pubmed publisher
	Kang S, Lim H, Andrisani O, Broxmeyer H, Kim C. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol. 2007;179:3724-33 pubmed
	Bürkle A, Niedermeier M, Schmitt Gräff A, Wierda W, Keating M, Burger J. Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia. Blood. 2007;110:3316-25 pubmed
	Ponte A, Marais E, Gallay N, Langonne A, Delorme B, Herault O, et al. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells. 2007;25:1737-45 pubmed
	Lisignoli G, Cristino S, Piacentini A, Cavallo C, Caplan A, Facchini A. Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. J Cell Physiol. 2006;207:364-73 pubmed
	Haas C, Martinez R, Attia N, Haines G, Campbell P, Koch A. Chemokine receptor expression in rat adjuvant-induced arthritis. Arthritis Rheum. 2005;52:3718-30 pubmed
	Lim H, Hillsamer P, Kim C. Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses. J Clin Invest. 2004;114:1640-9 pubmed
	Kohrgruber N, Groger M, Meraner P, Kriehuber E, Petzelbauer P, Brandt S, et al. Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands. J Immunol. 2004;173:6592-602 pubmed
	Sinha R, Mage R. Developing neonatal rabbit appendix, a primary lymphoid organ, is seeded by immature blood-borne B cells: evidence for roles for CD62L/PNAd, CCR7/CCL21, alpha4beta1 and LFA-1. Dev Comp Immunol. 2004;28:829-41 pubmed
	Annels N, Willemze A, van der Velden V, Faaij C, van Wering E, Sie Go D, et al. Possible link between unique chemokine and homing receptor expression at diagnosis and relapse location in a patient with childhood T-ALL. Blood. 2004;103:2806-8 pubmed
	Huber T, Reinhardt H, Exner M, Burger J, Kerjaschki D, Saleem M, et al. Expression of functional CCR and CXCR chemokine receptors in podocytes. J Immunol. 2002;168:6244-52 pubmed
	Campbell J, Qin S, Unutmaz D, Soler D, Murphy K, Hodge M, et al. Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire. J Immunol. 2001;166:6477-82 pubmed

product information

brand :

R&D Systems

master code :

MAB190

SKU :

MAB190-100

product name :

Human CXCR5 Antibody

description :

The Human CXCR5 Antibody from R&D Systems is a mouse monoclonal antibody to CXCR5. This antibody reacts with human. The Human CXCR5 Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Neutralization, Immunocytochemistry, CyTOF-reported.

target :

CXCR5

category :

Primary Antibodies

unit size :

100 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

51505

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human CXCR5, Met1-Phe372, Accession # P32302

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Stains human CXCR5 transfectants but not the parental cell lines in flow cytometry. Does not cross-react with human CXCR2, CXCR3, or CXCR4 transfectants.

gene symbol :

CXCR5

details of functionality :

ActivityAssaywCitation not found None None None None

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB190

accessionNumbers :

P32302

applications :

Flow Cytometry, Immunohistochemistry, Neutralization, Immunocytochemistry, CyTOF-reported

extended description :

Clone 51505 was used by HLDA to establish CD designation

2020 USD :

349

2021 USD :

369 USD

product details :

Clone 51505 was used by HLDA to establish CD designation

alt names :

BLR1, BLR1MDR-15, Burkitt lymphoma receptor 1, Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif)receptor 5), Burkitt lymphoma receptor 1, GTP-binding protein, CD185, CD185 antigen, chemokine (C-X-C motif) receptor 5, C-X-C chemokine receptor type 5, CXCR5, CXC-R5, MDR15CXCR-5, MGC117347, Monocyte-derived receptor 15

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.