product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Lipocalin-2/NGAL Antibody
catalog :
MAB1857-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
459 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
228418
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 1h
Lemecha M, Chalise J, Takamuku Y, Zhang G, Yamakawa T, Larson G, et al. Lcn2 mediates adipocyte-muscle-tumor communication and hypothermia in pancreatic cancer cachexia. Mol Metab. 2022;66:101612 pubmed publisher
Cheng M, Zheng Y, Fan Y, Yan P, Zhao W. The contribution of IL-17A-dependent low LCN2 levels to Helicobacter pylori infection: Insights from clinical and experimental studies. Int Immunopharmacol. 2023;124:110960 pubmed publisher
Huisman C, Norgard M, Levasseur P, Krasnow S, van der Wijst M, Olson B, et al. Critical changes in hypothalamic gene networks in response to pancreatic cancer as found by single-cell RNA sequencing. Mol Metab. 2022;58:101441 pubmed publisher
Mertens C, Kuchler L, Sola A, Guiteras R, Grein S, Brüne B, et al. Macrophage-Derived Iron-Bound Lipocalin-2 Correlates with Renal Recovery Markers Following Sepsis-Induced Kidney Damage. Int J Mol Sci. 2020;21: pubmed publisher
Braga A, Bandiera S, Verheyen J, Hamel R, Rutigliani C, Edenhofer F, et al. Combination of In Situ Lcn2 pRNA-RNAi Nanotherapeutics and iNSC Transplantation Ameliorates Experimental SCI in Mice. Mol Ther. 2020;28:2677-2690 pubmed publisher
Shao S, Fang H, Dang E, Xue K, Zhang J, Li B, et al. Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk. Front Immunol. 2019;10:746 pubmed publisher
Singh V, Yeoh B, Chassaing B, Xiao X, Saha P, Aguilera Olvera R, et al. Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer. Cell. 2018;175:679-694.e22 pubmed publisher
Fischer D, Seifen C, Baer P, Jung M, Mertens C, Scheller B, et al. The Fibrin Cleavage Product Bβ15-42 Channels Endothelial and Tubular Regeneration in the Post-acute Course During Murine Renal Ischemia Reperfusion Injury. Front Pharmacol. 2018;9:369 pubmed publisher
Smith J, Braga A, Verheyen J, Basilico S, Bandiera S, Alfaro Cervello C, et al. RNA Nanotherapeutics for the Amelioration of Astroglial Reactivity. Mol Ther Nucleic Acids. 2018;10:103-121 pubmed publisher
Choi Y, Zhou D, Barbosa A, Niu Y, Guan X, Xu M, et al. Activation of Constitutive Androstane Receptor Ameliorates Renal Ischemia-Reperfusion-Induced Kidney and Liver Injury. Mol Pharmacol. 2018;93:239-250 pubmed publisher
Xiao R, Chen R. Neutrophil gelatinase‑associated lipocalin as a potential novel biomarker for ventilator‑associated lung injury. Mol Med Rep. 2017;15:3535-3540 pubmed publisher
Gomez Chou S, Swidnicka Siergiejko A, Badi N, Chavez Tomar M, Lesinski G, Bekaii Saab T, et al. Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment. Cancer Res. 2017;77:2647-2660 pubmed publisher
Heuer J, Harlan S, Yang D, Jaqua D, Boyles J, Wilson J, et al. Role of TGF-alpha in the progression of diabetic kidney disease. Am J Physiol Renal Physiol. 2017;312:F951-F962 pubmed publisher
Shashidharamurthy R, Machiah D, Aitken J, Putty K, Srinivasan G, Chassaing B, et al. Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice. Arthritis Rheum. 2013;65:1064-73 pubmed publisher
Correnti C, Richardson V, Sia A, Bandaranayake A, Ruiz M, Suryo Rahmanto Y, et al. Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediated iron withdrawal in hematopoietic cell lines. PLoS ONE. 2012;7:e43696 pubmed publisher
Te Boekhorst B, Bovens S, Hellings W, van der Kraak P, van de Kolk K, Vink A, et al. Molecular MRI of murine atherosclerotic plaque targeting NGAL: a protein associated with unstable human plaque characteristics. Cardiovasc Res. 2011;89:680-8 pubmed publisher
Nairz M, Theurl I, Schroll A, Theurl M, Fritsche G, Lindner E, et al. Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2. Blood. 2009;114:3642-51 pubmed publisher
Nairz M, Fritsche G, Brunner P, Talasz H, Hantke K, Weiss G. Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium. Eur J Immunol. 2008;38:1923-36 pubmed publisher
product information
master code :
MAB1857
SKU :
MAB1857-100
product name :
Mouse Lipocalin-2/NGAL Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse Lipocalin-2/NGAL Antibody from R&D Systems is a rat monoclonal antibody to Lipocalin-2/NGAL. This antibody reacts with mouse. The Mouse Lipocalin-2/NGAL Antibody has been validated for the following applications: ELISA Capture,Western Blot,Neutralization,Immunoprecipitation,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry.
target :
Lipocalin-2/NGAL
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
228418
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Lipocalin-2, aa 21-200, Accession # P11672
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects recombinant mouse (rm)Lipocalin-2 in direct ELISAs and Western blots. In these formats, does not cross-react with rhLipocalin-1 or rhLipocalin-2.
gene symbol :
LCN2
top caption :
Detection of Mouse Lipocalin-2/NGAL antibody by Western Blot.
accessionNumbers :
P11672
applications :
Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry
USD :
459 USD
alt names :
24p3, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, HNL, LCN2, lipocalin 2, lipocalin 2 (oncogene 24p3), Lipocalin2, Lipocalin-2, migration-stimulating factor inhibitor, MSFI, neutrophil gelatinase-associated lipocalin, NGAL, NGALlipocalin-2, Oncogene 24p3, p25, Siderocalin, Uterocalin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.