Human NKp30/NCR3 Antibody | R&D Systems MAB18491 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human NKp30/NCR3 Antibody

catalog :

MAB18491

quantity :

500 ug (also 25 ug)

price :

579 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

210847

reactivity :

human

application :

western blot

more info or order :

R&D Systems product webpage

citations: 8

Reference
German Y, Vulliard L, Kamnev A, Pfajfer L, Huemer J, Mautner A, et al. Morphological profiling of human T and NK lymphocytes by high-content cell imaging. Cell Rep. 2021;36:109318 pubmed publisher
Carisey A, Mace E, Saeed M, Davis D, Orange J. Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells. Curr Biol. 2018;28:489-502.e9 pubmed publisher
Messaoudene M, Fregni G, Enot D, Jacquelot N, Neves E, Germaud N, et al. NKp30 isoforms and NKp46 transcripts in metastatic melanoma patients: Unique NKp30 pattern in rare melanoma patients with favorable evolution. Oncoimmunology. 2016;5:e1154251 pubmed publisher
Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, et al. NKP30-B7-H6 Interaction Aggravates Hepatocyte Damage through Up-Regulation of Interleukin-32 Expression in Hepatitis B Virus-Related Acute-On-Chronic Liver Failure. PLoS ONE. 2015;10:e0134568 pubmed publisher
Ferrari de Andrade L, Ngiow S, Stannard K, Rusakiewicz S, Kalimutho M, Khanna K, et al. Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma. Cancer Res. 2014;74:7298-308 pubmed publisher
Hershkovitz O, Rosental B, Rosenberg L, Navarro Sanchez M, Jivov S, Zilka A, et al. NKp44 receptor mediates interaction of the envelope glycoproteins from the West Nile and dengue viruses with NK cells. J Immunol. 2009;183:2610-21 pubmed publisher
Chen X, Trivedi P, Ge B, Krzewski K, Strominger J. Many NK cell receptors activate ERK2 and JNK1 to trigger microtubule organizing center and granule polarization and cytotoxicity. Proc Natl Acad Sci U S A. 2007;104:6329-34 pubmed
Warren H, Bettadapura J. A novel binding assay to assess specificity of monoclonal antibodies. J Immunol Methods. 2005;305:33-8 pubmed

product information

master code :

MAB18491

SKU :

MAB18491

product name :

Human NKp30/NCR3 Antibody

unit size :

500 ug (also 25 ug)

description :

The Human NKp30/NCR3 Antibody from R&D Systems is a mouse monoclonal antibody to NKp30/NCR3. This antibody reacts with human. The Human NKp30/NCR3 Antibody has been validated for the following applications: Bioassay,Epitope Mapping,Western Blot,Functional Assay,Agonist Activity.

target :

NKp30/NCR3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

210847

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse T cell hybridoma transfected with human NKp30 and Mouse myeloma cell line NS0-derived recombinant human NKp30 Fc Chimera

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human NKp30.

gene symbol :

NCR3

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Human NKp30 Antibody Induces IFN-? Secretion antibody in NK-92 Cells.

applications :

Bioassay,Epitope Mapping,Western Blot,Functional Assay,Agonist Activity

USD :

579 USD

alt names :

Activating natural killer receptor p30, CD337, CD337 antigen, CD337activating NK-A1 receptor, LY117,1C7NK-p30, lymphocyte antigen 117, natural cytotoxicity triggering receptor 3, Natural killer cell p30-related protein, NCR3, NKP30, NKp30MALS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage