Human NKp30/NCR3 Antibody | R&D Systems MAB1849 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human NKp30/NCR3 Antibody

catalog :

MAB1849

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

210845

reactivity :

human

application :

flow cytometry, blocking or activating experiments

citations: 5

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...; fig 5	Djaoud Z, Guethlein L, Horowitz A, Azzi T, Nemat Gorgani N, Olive D, et al. Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and ?? T cells. J Exp Med. 2017;214:1827-1841 pubmed publisher
	Herrmann J, Berberich H, Hartmann J, Beyer S, Davies K, Koch J. Homo-oligomerization of the activating natural killer cell receptor NKp30 ectodomain increases its binding affinity for cellular ligands. J Biol Chem. 2014;289:765-77 pubmed publisher
	Shi J, Tricot G, Garg T, Malaviarachchi P, Szmania S, Kellum R, et al. Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma. Blood. 2008;111:1309-17 pubmed
	Warren H, Bettadapura J. A novel binding assay to assess specificity of monoclonal antibodies. J Immunol Methods. 2005;305:33-8 pubmed
	Warren H, Jones A, Freeman C, Bettadapura J, Parish C. Evidence that the cellular ligand for the human NK cell activation receptor NKp30 is not a heparan sulfate glycosaminoglycan. J Immunol. 2005;175:207-12 pubmed

product information

brand :

R&D Systems

master code :

MAB1849

SKU :

MAB1849-100

product name :

Human NKp30/NCR3 Antibody

description :

The Human NKp30/NCR3 Antibody from R&D Systems is a mouse monoclonal antibody to NKp30/NCR3. This antibody reacts with human. The Human NKp30/NCR3 Antibody has been validated for the following applications: Flow Cytometry, Agonist Activity, CyTOF-ready.

target :

NKp30/NCR3

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

210845

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse T cell hybridoma transfected with human NKp30/NCR3 and Mouse myeloma cell line NS0-derived recombinant human NKp30 Fc Chimera

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human NKp30/NCR3 on cell transfectants and peripheral blood NK cells.

gene symbol :

NCR3

details of functionality :

ActivityAssaywCitation not found None None

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB1849

applications :

Flow Cytometry, Agonist Activity, CyTOF-ready

extended description :

Clone 210845 was used by HLDA to establish CD designation

2020 USD :

339

2021 USD :

359 USD

product details :

Clone 210845 was used by HLDA to establish CD designation

alt names :

Activating natural killer receptor p30, CD337, CD337 antigen, CD337activating NK-A1 receptor, LY117,1C7NK-p30, lymphocyte antigen 117, natural cytotoxicity triggering receptor 3, Natural killer cell p30-related protein, NCR3, NKP30, NKp30MALS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.